Antonio "Tony" Montana
- Adaptational Heroism: In spades. In contrast to his self-destructive personality in the film, Tony manages to be more self-conscious, remedying most of his more negative aspects and is fighting people far worse than him in terms of evil.
- Affably Evil: Despite being a ruthless drug lord, he treats his associates in a very friendly way.
- Anti-Hero: An Unscrupulous Hero.
- Anti-Villain: Compared with Sosa and Nacho, Tony has morals.
- Ax-Crazy: Of course, this side of his personality is still there. After learning that the Diaz brothers killed his mother, he completely loses his head and goes on a murderous rampage with a chainsaw. Furthermore, he is more than willing to wipe entire gangs with his Carbine Assault Rifle.
- Badass Baritone: Oddly enough, André Sogliuzzo gives him a lower voice pitch than Pacino.
- Badass Boast: Particularly in his dialogues.
- Badass in a Nice Suit: As expected from Tony Montana.
- The Don: Becomes one after Sosa's death.
- Earn Your Happy Ending: After Sosa's death.
- Even Bad Men Love Their Mamas: He loses it when he learns that the Diaz Brothers had his mother killed.
- Even Evil Has Standards: See Never Hurt an Innocent.
- Jerk with a Heart of Gold: Despite being rude and hotheaded, he's much more moral and good than other drug lords.
- Kick the Son of a Bitch: In the game, all his victims fall under this definition.
- A Lighter Shade of Black: Tony's still not a good person by any means, but he's practically a saint compared to most of his enemies. His refusal to hurt innocent bystanders alone puts him well above them.
- Made of Iron: He is practically unstoppable when he is angry enough.
- Never Hurt an Innocent: More than you expect from your average Sandbox game. While he has no problem murdering gangsters and cops, he completely refuses to murder innocents.
- Roaring Rampage of Revenge: Basically, the whole premise of the game can be summed up in this trope.
- Sanity Slippage: Averted. This time, Tony is much more sane, intelligent and reasonable.
- Spared by the Adaptation: Whereas Tony in the film is shot during the mansion shootout, here, he manages to kill his would-be assassin and flee his manor just as Sosa's and later the Police take over.
- Took a Level in Kindness: One of many ways he's learned from his mistakes.
- Villain Protagonist: Less so than the film, but he's still a ruthless drug lord, after all. In fact, the whole premise of the game revolves around his forming the most powerful drug empire in Miami, eliminating his rivals in the process and finally becoming the most powerful man in Miami.
- Woobie, Destroyer of Worlds: Even more evident than before in the film. After the death of Manny, his sister and especially his mother, Tony is clearly devastated.
A mysterious, yet friendly drug lord who has drug business in the islands.
- Affably Evil: Despite being a hardened drug lord, he's very friendly, polite and civil.
- Arch-Enemy: To Sosa and the Colombian Cartel.
- Badass in a Nice Suit: He wears a nice suit and is very capable in a gunfight, after all.
- Bald of Awesome: He's bald and one of the most badass characters in the game.
- Cool Shades: He never takes off his sunglasses.
- Expy: He has a lot of features in common with Manny Ribera, such as the same vivid colors in his suit and the fact that he's voiced by Steven Bauer, the same actor who played Manny in the film.
- Foil: To Sosa. Both are the biggest drug suppliers and both maintain a friendly and civil attitude towards people, but while Sosa is disloyal, cold and ruthless, the Sandman is loyal and never acts against Tony.
- Rule of Cool: He's seems to live around this trope.
Alejandro "Alex" Sosa
The main antagonist of the game, as well as Tony's main target.
- Arch-Enemy: To both Montana and the Sandman.
- Authority Equals Asskicking: Should one pass on the chance of using Rage Mode during thr shootout against him, he can and will give Tony a run for his money. Pretty impressive for someone who's only been sending his goons to deal with Tony up until this point.
- Big Bad: While he's in a Big-Bad Ensemble with Gaspar Gomez and Nacho Contreras, Sosa is the Final Boss.
- Defiant to the End: Even when Tony has him at gunpoint, in his own mansion, and after wiping out the last of his goons and high ranking associates (prety much crippling his empire), he still tries to taunt his former associate, completely in denial of his defeat.
- Evil Sounds Deep: In this game, his voice is even deeper thanks to Robert Davi's delivery.
- Final Boss: He is the final enemy to kill throughout the entire storyline.
- Karma Houdini Warranty: In the video game, Tony's survival is the beginning of the end for him, and Tony proceeds to destroy his entire enterprise and biggest allies before cornering him in his own mansion in a reflection of the film's climax.
- Villainous Valor: Despite Tony wiping out his private army and cornering him in his own mansion, he decides to make a last, desperate stand by attempting to shoot it out with his former associate.
- Affably Evil: Unlike Sosa and Nacho, he has a very civil, casual demeanor.Gaspar: I heard about your mother. Montana. I just wanted to pass along my condolences and to say that the Diaz Brothers got what's coming to them.
- Big-Bad Ensemble: With Sosa and Nacho Contreras.
- The Dragon: To Sosa.
- Even Evil Has Standards: Saying that the Diaz Brothers deserve what happened to them.
Nacho "El Gordo" Contreras
- Adaptational Villainy: In the film, Nacho barely appears and only had a brief cameo. In the game, however, he's pure evil.
- Asshole Victim: After being shot by Tony himself, this bastard is devoured by a shark seconds later.
- Bad Boss: He clearly forced several people to work in their illegal business.
- Big-Bad Ensemble: With Sosa and Gaspar Gomez.
- Dirty Coward: He is an absolutely depraved man, but when the gunfight starts, he runs and sends his minions.
- Fat Bastard: He is obese and a ruthless drug lord and human trafficker.
- Hate Sink: Unlike Sosa, he absolutely lacks of cool qualities, being a man who would do things like raping (or beating) women, killing women and human trafficking. He's also a Dirty Coward.
- Politically Incorrect Villain: He calls Tony "a Cuban piece of shit."
- Rape Is a Special Kind of Evil: Tony is visibly disgusted when he learns that Nacho has a reputation of raping women.
- Slavery Is a Special Kind of Evil: Possibly. He's a human trafficker, after all.
- Would Hit a Girl: If Venus's dialogue is any indication.
The SkullOne of Sosa's most trusted hitmen, who helps lead the assault on Tony's mansion at the beginning of the game.
- The Cameo: In his short screentime, he's shown approaching Tony from behind, much like in the film. Here however, Tony fills him with lead before he can even fire a shot on his intended victim.
- Cool Shades: He's always seen wearing a pair of sunglasses, even at night. Makes him look very similar to a Terminator.
- The Dragon: To Sosa. He does whatever dirty work Sosa doesn't want to do.
- Death by Adaptation: Whereas he gets away with killing Tony in the film, here, he gets shot for his trouble.
- Karmic Death: Tony blasts him with his assault rifle before he can fatally shoot him.
- Laser-Guided Karma: Here, he's taken out by Tony in the first mission, setting the stage for Tony's Roaring Rampage of Revenge against Sosa.
- The Quiet One: Doesn't speak much, if at all.
- Shotguns Are Just Better: Wields a shotgun during the assault on Tony's mansion.
- Starter Villain: The first major villain Tony is shown fighting, and is also the first to go down.