- Voiced by: Sanae Fuku (Japanese), Megan Shipman (English)
A girl visiting her aunt in Cenancle Island, Nene is one of the few people in the world to own a full-body prosthesis. She meets Uzal and Clarion on the trip to the island, and after getting involved with the chaos that BUER causes, finds herself Clarion's new "owner" and caretaker.
- Achievements in Ignorance: Nene's so adept in making use of her cyborg body that she's capable of things other people would normally think would be impossible.
- For example, in the penultimate episode, she helps Bunny hack the Imperial American security protocols so that they could get out of the incinerator they were trapped in. When they finally get out, Bunny THEN realizes that the jury-rigged console she made wasn't even plugged in into Nene. This meant that Nene used her own remote access system unknowingly to deactivate the incinerator.
- Berserk Button: She's very protective of Clarion.
- Cuteness Proximity: She literally goes ga-ga over Clarion, and it doesn't take much to get her to cooperate with Uzal's zany scheme because it gives her the chance to be close to Clarion.
- Cyborg: Her brain was transplanted into a mechanical body because of a severe illness (in the mangua it is called "Pyxis Syndrome") and/or an accident (the manga itself and the volume descriptions send mixed signals). Since the technology is in its infancy, her body has obvious joints which can lead to her being mistaken for an android.
- Elegant Gothic Lolita: The look of her Magical Girl-style "optical camouflage" uses elements of this.
- Gamer Chick: Nene became an expert in handheld games as part of her physical therapy regimen. Her gaming proficiency also allows her to instantly distinguish between VR simulations and real life.
- Harmful to Minors: She apparently saw her parents die in a house fire (which was the reason why she was so eager to run towards danger to save Uzal and Clarion).
- Heroic Sacrifice:
- Nene volunteers to take Clarion's place and shut down BUER's main body once it goes berserk in the final episode. Obviously, it doesn't stick, as she DOES manage to stop BUER in time, and gets returned to Clarion unharmed.
- Apparently her parents saved her from a house fire at the cost of their lives.
- Hour of Power: While the abilities Nene gains from the Pandora Device are comparatively useful, they also have a time limit.
- Instant Expert: As an Adepter, she's able to make use of her cyborg body far better than it should be possible. This trope is also invoked whenever she uses the Pandora Device to perform any profession.
- Jumped at the Call: Really, she could have just easily walked away when the initial Cenancle Island attacks happened, but nope, she just had to go back and make sure Clarion was safe.
- Skilled, but Naïve: A master at anything gained from the Pandora Device, trusts someone she just met too easily.
- Wide-Eyed Idealist: She'll do anything for WORLD PEACE!
- Later on, she enthusiastically declares to Kurtz that she'll use the power of MONEY to BUY world peace.
Uzal's long-suffering assistant, Clarion is another full-body cyborg like Nene. Unlike Nene, her body's been specially modified to hold Uzal's Pandora System, which can grant mastery of a wide array of skills. She eventually joins Nene, when the latter becomes her new registered "owner" care of Uzal.
- Berserk Button: She doesn't like it when people touch her ears. Someone tried and got their (cyborg) arm cut off. She's also very protective of Nene.
- Cyborg: Unlike Nene though, who actually does humanlike activities like eating or sleeping, Clarion doesn't seem to sleep, and what's more prefers to be plugged in (via old-style electric cord!) and charged overnight to gain her energy.
- Grumpy Bear: Tends to act surly around everybody.
- In-Series Nickname: Nene calls her "Cla-rin", to her disgruntlement. Due to this, every person they meet calls her "Cla-rin" as well. Seven Seas' translation of the manga spells it "Clara-rin", and Funimation spells and pronounces it "Cla-ring".
- Knight in Shining Armor: Nene has come to think of Clarion as her "cat prince" after Clarion saved her life during the Hermes department store fire.
- Little Miss Badass: While Clarion's been shown to be fully capable of defending herself and Nene in the various scrapes that they get into, nowhere was this shown more when she decides, on her own volition, to pre-emptively assault the Imperial American forces occupying Uzal's underground facility.
- Living Emotional Crutch: When Clarion becomes separated from Nene, Nene worries that Clarion has become this to her.
- Ninja Pirate Zombie Robot: She's is a full-body Cyborg Cat Girl Ninja Maid.
- Noodle Incident: She's very self-conscious about people wanting to touch her cat ears. She doesn't want to explain why.
- Skewed Priorities: In the first episode, she loses her left arm while protecting Nene from an excavation robot's attack. She didn't mind (temporarily) losing an arm. The fact that she lost her arm to a mere excavation robot is what vexes her so.
- There Is Another: In the final episode, Vlii— discovers a whole room full of Clarions, sleeping in pods. Whether these are just extra bodies, or Clarion ISN'T really a cyborg that she claims she is, is not made clear.
- Uzal apparently built another android or cyborg of the same model as Clarion. It's/She's called "Phobos" and is a former (?) operative of the villainous organization "Poseidon".
Clarion's "master" and owner prior to Nene, Uzal is a well-known personality on Cenancle Island, being both an inventor who contributed to the island's known infrastructure and a philanthropist. At least, at least as far as the public is concerned anyway, but as Nene soon finds out, there's a whole lot about Uzal's private affairs that would be considered ethically dubious. It is under her final command that Clarion is placed under Nene's care.
- Ambiguous Situation: In the final episode, we see what seems to be Uzal appearing before Kurtz, which distracts him long enough for him to get buried by the rubble from the collapsing underground base. And it's STILL not made clear whether it's really Uzal, or another of her holographic projections.
- Blatant Lies: Suuuuure Uzal, Nene really did pass out that one time, and you didn't do any illegal modifications on her while she was unconscious.
- Color Failure: Out of exasperation after her rebellious subordinates break into her lab to beg her to bring BUER under her control again including an recursive case of Giving Up the Ghost.
- Crazy-Prepared: One module was destroyed? Fear not, she has several more in reserve! No way out of a self-destructing lair? Fear not, she prepared an escape route beforehand!
- Gender-Blender Name: Uzal is a male name from the Hebrew Bible.
- Hot Scientist: She certainly fits the bill, with a dash of Mad Scientist. It helps that we're first introduced to her while she's sunbathing in a bikini.
- Labcoat of Science and Medicine: The coat she wears over her minidress looks mostly like one, except that the hem and cuffs are split apart like the petals of a flower.
- The Mentor: Before she was believed to have died, she acted as a mentor figure to Nene, making Nene aware of her potential as an adeptor, and entrusting Nene with Clarion, the key to unlocking her abilities.
- Names to Run Away from Really Fast: It's probably not a good idea to trust someone called Delilah.
- Never Found the Body: The local media assumes that she was one of those killed during the "terrorist attack" at Cenancle Island, to the point where there's a public memorial held in her honor.
- Reformed, but Not Tamed: Even though she left the real Big Bad, the villanous organization "Poseidon", she is often ready to use questionable means and is a real dick to her subordinates (who mostly deserve their treatment, though) but her close associates know she wouldn't do something really evil (e.g. Takumi knew that the black-box devices installed by Uzal in Nene's cyborg body wouldn't be dangerous to Nene in any way because they were made by Uzal).
Nene's aunt, who's a contemporary of Uzal. Much like Uzal, she's a bit quirky and strange. She holds major stakes in many of the private enterprises located in Cenancle Island.
- Ass Shove: When she got food poisoning from eating an expired chocolate bar, one of the treatments Nene tried to use (after she installed the knowledge to act as a paramedic) was an suppository.
- Berserk Button/Ma'am Shock: She may be Nene's aunt, but she doesn't like being called "oba-san" (Auntie).
- BrainComputer Interface: She's an early adopter of cyber-brain technology, and as such has the associated ports at the back of her neck that anyone who's familiar with Ghost in the Shell would recognize immediately.
- Hikikomori: Takumi is usually overwhelmed with social anxiety and has to hide behind her Gertsecommas whenever somebody sees her face-to-face. She does all her work in cyberspace and never leaves her mansion.
- Mad Scientist: She holds key patents, funds important research and is extremely influential in the business world, but she looks and acts like a bratty child. She also has an obsessive rivalry against Uzal.
- Reformed, but Not Tamed: Just like her former colleague (and possible love interest), Uzal, she was a member of the villainous organization "Poseidon", defected from it, but was still ready to use questionable means to achieve her aims.
- Uncle Pennybags: Takumi provides Nene and Clarion with maintenance for their bodies at the hospital she owns, gives Clarion access to heavy weapons when she sets out to raid Kurtz's base, and in the manga, buys out a whole stadium that Nene can use for her PE assignment.
- Verbal Tic: "-daya!" Both Seven Seas and Funimation translate this as "yeah!"
- Voiced by: Junpei Morita (Japanese), Sonny Strait (English)
A giant boring robot owned by Uzal's company that possesses a giant laser. While its main body resembles a giant eyeball, its Central Nervous Unit, which detaches itself after the main body is shut down, takes the form a gentlemanly but perverted lion-esque creature with three legs.
- Antiquated Linguistics: The Central Nervous Unit speaks in archaic Japanese, which is usually translated as Ye Olde Butcherede Englishe.
- Butt-Monkey: The CNU, whether it's because of Takumi wanting to dismantle him to find out how he works, or Clarion locking him up in a safe to prevent Takumi from dismantling him, or inflicting Amusing Injuries on him for being a Lovable Sex Maniac.
- Fun with Acronyms: B.U.E.R stands for "Base of Unearth Extra Resources".
- Insistent Terminology: As the CNU is based on a demon that teaches philosophy, he is "The Philosopher of Hell", thanking you kindly.
Colonel Ian Kurtz
A "security adviser" from Imperial Americana brought in to monitor Cenancle Island's stability. He is secretly trying to gain access to BUER's main body, and the constant network disruptions experienced by the island are an indirect result of his subordinates trying to hack through BUER's systems.
- A God Am I: After he was denied control over BUER, his combat robot Fear was destroyed, his subordinates neutralized and he himself apparently discharged from the Imperial American military, he went off the deep end and wanted to kill everyone with a land-mate (a combat mecha) for rejecting the "god of the new world", him.
- Big Bad
- Schedule Fanatic: He always carries a pocket-watch and constantly reprimands people for being late.
- The Stoic
- Smug Snake: He spends most of the series believing that he's got the situation at Cenancle Island under his control, when it turns out that he's been out-maneuvered and played by Uzal the entire time.
- Villainous Breakdown: Loses it when he finds out that all that time spent trying to hack through BUER's security protocols only netted him... BUER's secret photo collection of low-angle shots of girls' thighs. In essence, he spent 12 episodes trying to get into an AI's Porn Stash.
A high-ranking member of the Cenancle Defense Force. He spends his free time out of uniform helping out the folk in Cenancle,
- A Father to His Men: He's well-liked and greatly respected by his subordinates.
- Badass Normal: He's a highly competent martial artist who was able to go toe to toe with powerful battle androids despite being just a normal uncyborgized human being.
- Nice Guy: He has a habit of helping others in need. His reason for doing so? "It's just in my nature!"
- Voiced by: Satsumi Matsuda (Japanese), Alex Moore (English)
A television reporter who always get interrupted before she can state her name.
- Butt-Monkey: So far, she has suffered a great deal of pain and misfortune, from almost drowning to getting caught up in explosions, being unable to pay for her beer and wearing a mascot uniform that's too heavy for her. And she still hasn't said her full name yet!
- Catchphrase Interruptus: She is constantly getting interrupted before she can say her name.
- Contrived Coincidence: She always happens to be right at the center of whatever chaos is happening with Clarion and Nene, and always, always, always fails to get the scoop because she's horribly physically traumatized in the process of trying to film, record, or otherwise exploit it, before she even gets to say her full name and title.
- Cute Little Fang
- Ms. Exposition: Her main purpose in the story is to deliver information about events on Cenancle until she gets interrupted by her Butt-Monkey tendencies.
- Red Shirt Reporter: Parodied as she is almost killed on a regular basis. Subverted because she always survives.
A combat robot that serves as Kurtz's personal bodyguard.