For the characters in original manga an other adaptations see: Dororo
Voiced by: Hiroki Suzuki
- Absolute Cleavage: Hyakkimaru starts much more covered up than how he's designed in the manga, but he loses the Badass Cape and scarf after several episodes, rendering him just as exposed as his earlier counterparts.
- Adaptational Attractiveness: None of Hyakki's adaptations feature him as ugly by any means, but the 2019 rendition of Hyakkimaru is much younger looking and far less muscular. The intention was to make him look "cuter" for that version.
- Adorkable: The more gentle moments when he doesn't know how to deal with things people take for granted. In episode 2, Dororo has to stop him from eating fish raw right off his sword arm. He steps in the fireplace with his own leg, burns it and tries again after wondering how that happened for a moment. Later, Dororo covers his newly regained ears with a piece of cloth and ties it with a bow on the top. When Mio asks him to speak, he closes his mouth and sticks fingers in his ears in refusal.
- Affectionate Nickname: Called "Aniki"/"Bro" by Dororo during their travels.
- Age Lift: Inverted. Interestingly enough, despite his younger and less muscular looks, he's older in the 2019 anime - sixteen years old, while his manga counterpart was fourteen.
- Ambiguous Gender: Not him, but everyone to him. Since he only sees soul energy, he can't discern between men and women and only goes by the good or bad colors of the soul. This is only really the case in the 2019 version; in other adaptations and in the manga, he can somehow tell boy from girl (except for Dororo) even before he gets his sight back.
- Artificial Limbs: And ears, and eyes, and nose...
- Attack! Attack! Attack!: At least in the 2019 adaptation, this seems to be his go-to strategy for dealing with demons. He won't stop until his target is killed, disregarding anything that might happen to him or to those around him as long as no one is in immediate danger. Jukai wonders if this isn't because he can't feel pain, and therefore has no normal self-preservation. Eventually, this crosses over into Fearless Fool territory as he gets more of his parts back, as his injuries end up becoming more debilitating for him. This comes back to bite him in the butt hard when he rushes to fight the Arijigoku (antlion demon) while injured twice. The first time he gets his real foot bitten off. The second time, he ends up leaving Mio and the kids undefended.
- Badass and Child Duo: The Badass to Dororo's Child.
- Badass Normal: It's hard to believe he's a regular human when he slays the biggest and baddest demons that no normal man could ever dream of fighting.
- Berserker Tears: Hyakkimaru does not take the death of Mio well in any of the adaptations. In the 2019 anime he also briefly sheds tears as he delivers the killing blow to the Arijigoku.
- Bishōnen: Hyakkimaru in the 2019 anime is basically a living, life-sized ball-jointed doll, and he has a face to match.
- Blade Below the Shoulder: Hyakkimaru's prosthetic arms conceal a pair of katana.
- Blind Seer: While he has no eyes, he does have the ability to see the souls, which helps him get by despite the absence of every other sense.
- Blind Weaponmaster: With the weapons as part of his body, no less.
- The Corruption: The boy's soul is mostly white, but streaks of red are always present and threaten to get larger if he doesn't get placed in check.
- The Determinator: His defining trait. No matter what, he always has the strength to persevere. Daigo Kagemitsu muses to himself in the final episode that this was why the twelve demons wanted his body so badly — they were drawn to that strength.
- Detect Evil: Like with Biwa-Houshi, he can sense the energy of others and can tell what is edible, good/neutral, and evil.
- Disabled in the Adaptation: While manga Hyakkimaru and 2019 anime Hyakkimaru are missing all the same parts, 2019 Hyakkimaru lacks most of the telepathic abilities the former had to bypass his lack of ears and vocal cords. Thus he starts the series off as entirely deaf and mute, whereas his manga counterpart could at least communicate verbally.
- Disability Superpower: His lack of a central nervous system while piloting his prosthetic body in the 2019 adaptation actually gives him an edge in battle, as he feels no pain, making him an unhesitating killing machine. It's an interesting take on the anime, since his quest to become more human gives him back these senses, among other problems.
- Dual Wielding: In episode 23, Hyakkimaru gains both of his arms back and plays this trope straight by using his wraps to cover his hands to hold onto both of his blades since they don't have handles. And since he has his real arms back, Tahomaru notes that Hyakkimaru's reach is longer as a result.
- Earn Your Happy Ending: He goes from hell and back since he was born, losing his body parts, attracting demons since childhood, losing his first love, brother, mother and adoptive father but he is able to fully regain his body, make peace with his brother and mother before they die and successfully resist become a demon himself. He ends the series wandering alone to discover what it means to be human but it's implied that he meets an adult Dororo later on.
- Eerie Pale-Skinned Brunette: In the 2019 adaptation.
- Feel No Pain: As a side effect of having a prosthetic body, Hyakkimaru can survive sword cuts and stabs without so much as flinching. In the remake at least, his sense of pain was one of the things taken from him. He gets it back after killing Bandai in episode 2. He at least discusses this trope in the manga, saying that because he has no pain threshold he also has no idea how much his body can take before giving out.
- Jukai notes that since Hyakkimaru doesn't feel pain, he fights without fear and picks fights without any consideration. He keeps that trait even when regaining his ability to feel pain.
- He Who Fights Monsters: According to Biwa-Houshi. He warns Dororo that Hyakkimaru might become the same as the demons he fights. Dororo actually leaves Hyakkimaru after calling him the same as the demons he fights in episode 15.
- Hellish Pupils: In the 2019 anime, Hyakkimaru and Dororo have the same dark red eyes, but Hyakkimaru's eyes alternate between having slit demonic pupils when he is fighting and round human pupils when calm or emotional.
- Hiding the Handicap: Averted in the 2019 version, where he's so isolated from the rest of the world that he can't even begin to hide it.
- It's All About Me: Due to the reveal that his own father took away his body parts in a deal with the demons, Hyakkimaru spitefully refuses to think about the consequences about killing demons will have on others. This attitude actually disgusts Dororo enough in episode 15 that she leaves him. This continues till the final episode when he spares his little brother as realizing Tahōmaru's not that different from him.
- Lightning Bruiser: He's very agile and outclasses many demons with his speed. He also packs quite the punch.
- Magic Is a Monster Magnet: Has a tendency to draw ghouls and demons to him, hence why Jukai saw it necessary to teach him how to fight.
- Meaningful Name: Hyakkimaru's name 百鬼丸 contains the kanji for "hundred demons."
- No Sense of Personal Space: Growing up deaf, blind, and mute, Hyakkimaru doesn't have a lot of options for communication. So when he does reach out to others, it's usually by touch—whether his theoretical conversation partner is comfortable with it or not.
- No Social Skills: In the 2019 anime. Growing up deaf, mute, blind, and largely isolated from people didn't exactly do much for his communication skills, verbal and nonverbal. After regaining most of his senses back and learning the bare-bones of vocabulary he becomes curious of the world and often approaches it with a childlike wonder.
- Roaring Rampage of Revenge: When Mio and the children are killed by a group of samurai who assumed she was a spy, Hyakkimaru returns to find them slaughtered and goes berserk and brutally killing the ones responsible.
- Sacrificed Basic Skill for Awesome Training: Hyakkimaru is ridiculously skilled at killing demons due to Jukai's training and experience but due to his disabilities he has no social skills or even understanding of the world around him before he met Dororo.
- Samurai Ponytail: A messy one that hints at his heritage.
- Screaming Warrior: Downplayed in the anime but he's gained this status once he got his voice back, baying with grief during his Extreme Mêlée Revenge against Mio's killers and doing so to call for Dororo during the Nokosaregumo fight. It might be in part because he hasn't quite gotten the hang of articulating words yet.
- Sleeps with Both Eyes Open: Having lived most of his life without eyelids, Hyakkimaru hasn't gotten into the habit of closing them while he sleeps. Luckily, he doesn't have real eyes to bear the damage.
- The Speechless: Even after regaining his voice at the end of episode 5, he's reluctant to use it, as he finds the sound of his own voice unpleasant—and only knows about four words. He starts to speak more by Episode 13.
- Suddenly Voiced: His first words aren't all that great, considering his was reeling from his first love's death:"Mi...o..."
- Terse Talker: 2019 Hyakkimaru gradually becomes one. Even after he starts getting the hang of speaking, he often drops nouns, only uses simple present tense, and tends to resort to sentence fragments when speaking about direct or indirect objects he can't omit entirely. Eventually he grows out of this as time progresses.
- Unstoppable Rage: While generally quiet there are a few situations that bring him to a blinding rage:
- In episode 6, after coming back to see Mio and the kids she was taking care of being murdered, he loses it and slaughters the samurai responsible. He nearly loses it when the samurai responsible for her murder appears in front of him in episode 12.
- He explodes in rage when he realizes that Sabame is just like his father and is obsessed with killing all the demons he can find in episode 15.
- He screams in fury when he realizes that his arms and eyes have been transplanted on to his brother and his attendants. To highlight this, his aura is blood red, indicating he is very close to becoming a demon.
- Villain Protagonist: Averted as all he wants is to reclaim his body due to his Jerkass father and as a benefit helping innocent people threatened by the demons that hold his body parts, but he is viewed as this to Daigo's country due to the fact that retaining these attributes threaten the existence of the innocent people that prosper in his father's land by lack of rain for crops and people dying due starvation and sickness.
- Walking the Earth: In the final episode, he leaves Dororo to understand what it means to be human, though it's heavily implied they reunite in the future.
- Wild Child: In the 2019 anime, as his lack of senses made it difficult to communicate with what little human contact he had growing up. Not only does he have No Social Skills, he doesn't even have language.
- Wonder Child: Especially in the 2019 anime, where Jukai discovers him while on the verge of a Despair Event Horizon in a manner implying that the Buddha brought them together.
- Would Hit a Girl: In contrast to his manga counterpart, in the 2019 version Hyakkimaru has less reservations about killing women, given the second monster we saw disguised itself as a woman, but that can be justified as he can't see or distinguish between male and female soul energy.
Voiced by: Rio Suzuki
- Adaptational Attractiveness: The character design in the anime makes the kid look more conventionally cute instead of scrappy.
- Adaptational Nice Guy: In the 2019 anime adaptation, most of Dororo's reckless and Hot-Blooded tendencies are removed and he is far kinder and more worldly than the manga version, often acting as a genuine caretaker for Hyakkimaru who struggles with anything other than demon-slaying.
- Badass and Child Duo: The Child to Hyakkimaru's Badass, at least in the tellings that keep Dororo a child. The kid is not without spunk, however.
- Broken Pedestal: Hyakkimaru's increasingly obsession with killing all demons without regard for the consequences actually disgusts Dororo so much that she leaves him in episode 15.
- The Caretaker: Being blind, deaf and lacking in social skills, Hyakkimaru can't fully take care of himself outside of hunting, so when Dororo joins him the kid basically acts as his eyes and ears, often feeding him and keeping him out of danger as well. A far cry from the Protectorate Dororo was in the original.
- In #19 he has an argument with Hyakkimaru over why he shouldn't be randomly grabbing people's faces to greet them and it sounds exactly like a parent scolding their child. It even ends with Because I say so.
- Character Title: The one and only.
- Distressed Dude: Or more accurately Damsel in Distress though her kidnappers didn't know so. At the end of episode 15, Dororo gets kidnapped by Itachi and his men to search for the treasure that her parents hidden.
- Does Not Like Shoes: Never wears sandals, or any kind of footwear for that matter. Not unless ankle wraps count.
- Establishing Character Moment: Dororo's first scene has him trying to sell goods from a group of bandits that he stole from, before easily outmaneuvering them and running away. Later, he comes across a hungry dog, and while Dororo does warm up to the creature, he tells them that he can't give it food or how else will it learn how to survive? This highlights Dororo's thievery skills, love for money, but also that he does have a warm heart deep down and only wants to survive in this hard world.
- Living Emotional Crutch: As Hyakkimaru is emotionally stunted and on the borderline between human and demon in the 2019 anime, Dororo represents his humanity and connection to the outside world.
- Made of Iron: Dororo can take one hell of a beating, and then walk it off like a boss.
- Momma's Boy: Like most children her age, Dororo deeply loves his mother. It helps that she died early keeping her alive. Generally Dororo lowers her guard if he meets people that resemble his mother.
- Morality Chain: He is there to make sure Hyakkimaru doesn't become the same as the demons he fights. Hyakkimaru even acknowledges Dororo as his tie to being human.
- Never Learned to Read: He's rather impoverished and never had the oppportunity to learn. We regularly see him asking other people what certain plaques say throughout the story.
- Only Friend: Dororo is Hyakkimarus first and only friend he ever made since he doesnt have many friends close to his age and he lacks social skills.
- Please Don't Leave Me: In episode 9 Dororo catches an illness, a kind nun lets Dororo sleep in her monastery. He wakes up as Hyakkimaru is out getting water and freaks out that Hyakkimaru left while Dororo waz sleeping.
- Pragmatic Hero: Dororo spends the early part of the series trying to sell Hyakkimaru's demon slaying as a service as after all they have to eat. This stops after Dororo's finds her parents' treasure.
- Raised as the Opposite Gender: Unlike in the manga where Dororo didn't even know she was a girl, in the anime she was aware the entire time, but was still raised as a boy and doesn't want anyone to find out the truth.
- Shameful Strip: Itachi and his men forcefully strip down Dororo naked to find the map somewhere on Dororo's body only to discover her true sex and the missing half of the map. This leaves Dororo ashamed and disgusted after Itachi and his men saw her body.
- She Is All Grown Up: The last moments of the final episode show a teenage Dororo.
- Strong Family Resemblance: To his mother, especially noticable when she is a teenager in the epilogue, sporting her hair in the same way and wearing a similar outfit.
- Supporting Protagonist: Dororo serves as the heart of the story and primary nurturer of Hyakkimaru's morality.
- Tagalong Kid: Dororo simply tags along without Hyakkimaru's say-so.
- Treasure Map: The tattoo on Dororo's back reveals that it is a map to treasure, drawn on her back by her parents.
- Unsettling Gender Reveal: Averted in the 2019 adaptation, as the creators have gone to say they're not trying to hide Dororo's sex and gender this time around, and Hyakkimaru is informed of the truth by a nun taking care of her when she is sick. However, Dororo is worried about this and asks Hyakkimaru if he was told anything, to which he doesn't answer.
Voiced by: Mutsumi Sasaki
- Blind Weaponmaster: He's a master swordsman despite being completely blind.
- Cool Old Guy: Definitely elderly, but he can still take down demons with a single swing of his sword.
- Detect Evil: Being blind doesn't stop him from detecting the energy of beings, especially demons. Hyakkimaru also shares this ability with Biwa-Hoshi.
- Handicapped Badass: He's blind, but he's still capable of killing demons with one slice.
- Hidden Weapons: His biwa holds a blade.
- Master Swordsman: Despite his age, he is a very skilled swordsman.
- Mysterious Past: We never do learn anything about his past besides that he's from the samurai class in the final episode. It definitely explains his skill with a blade and might even explain his blindness.
- Named by the Adaptation: In the original manga he was never named, but the final episode gives his name as Biwamaru.
- Nice Guy: He cares about the well being of Dororo and Hyakkimaru.
- Single-Stroke Battle: In the manga, he demonstrates to Hyakkimaru how to fight by slicing a fly in half. In the first episode, a demon challenges Biwa-Hoshi and is dealt with similarly.
- Wrecked Weapon: He broke the blade of his sword when moving a boulder to save Dororo from drowning. The handle is still attachable to the biwa, but the blade is currently broken and unusable.
Voiced by: Akio Ohtsuka
- Adaptation Expansion: In the 2019 anime his character is greatly expanded upon, having worked under a samurai until he was so horrified he threw himself into the sea out of despair.
- Adaptational Villainy: In the manga, all that is said of Jukai is that he's a doctor. In contrast, the 2019 anime gives Jukai a backstory where he used to work for a brutal warlord and was responsible for the crucifixion of would-be rebels.
- The Atoner: How he feels after being rescued by a foreign ship, opening a free clinic in a village afterwards. He committed his life to helping others affected by the war and crafting prosthetic limbs. Even after he became a vagabond he traveled battlefields using his prosthetics as a token to the bodies who were mutilated.
- Bungled Suicide: After having enough of working for the warlord, he threw himself off a cliff hoping to die. He not only survived the fall but was rescued by a foreign ship.
- Death by Adaptation: He's alive in the original manga, anime, and video game, but in the 2019 anime, he decides to die with Nue and Tahomaru in the burning castle falls around them.
- Due to the Dead: He spends most of his time now wondering battlefields and fitting the corpses with his prostheses so they're presentable.
- Death Seeker: In the 2019 anime he became so lost and fatalistic that demons didn't notice him because he lost the will to live.
- Heroic BSoD: His apprentice Kaname leaving in disgust when he discovered Jukai's history essentially broke him and he spent the day wandering in a daze. He only broke out of it when he found Hyakkimaru.
- My God, What Have I Done?:
- After seeing a woman get mercilessly cut down by his lord for simply begging to not have her husband crucified, Jukai has this reaction and tries to commit suicide by throwing himself off a cliff in the flashback of episode 3 for the 2019 anime.
- He has another one after realizing he taught Hyakkimaru only how to kill and wonders if he just repeated his past mistakes.
- Parental Substitute: The closest thing Hyakkimaru has to an actually good father. He found baby Hyakkimaru and raised him. Hyakkimaru even says he's his "mother," which Jukai is both moved and amused by.
- Reformed, but Rejected: All of his apprentice's goodwill towards him dries up when he learns of Jukai's past. Even after being talked down from killing Jukai on the spot, the boy refuses to forgive him and casts aside his prosthetic leg before walking away for good.
- Tears of Joy: After reuniting with Hyakkimaru, this is his reaction after Hyakkimaru calls him his mother, It Makes Sense in Context.
Voiced by: Chie Nakamura
- Adult Fear: She lived it when her firstborn son was born skinless, eyeless and limbless and told that he doesn't have much time to live.
- Broken Bird: Seeing her first son become skinless, eyeless and limbless right after his birth and then her husband taking him away to die away from her, essentially broke her. Despite her land being prosperous and having a second son, she spends her days praying in depression.
- Death by Adaptation: Survives in the original manga but chooses to die with Tahōmaru in the final episode.
- Driven to Suicide: In episode 12 after meeting a grown up Hyakkimaru, she begs for his forgiveness for the horrible things they did to him and the fact that they still need the demons to survive. But she attempts suicide so he isn't the only one to suffer. She survives the attempt but is bedridden in the process.
- Heroic Self-Deprecation: She feels that's powerless and can't do anything to help Hyakkimaru or Tahōmaru despite being their mother.
- Lady Macbeth: She's an inversion. She's not ambitious at all and in fact is regretful over what they did to Hyakkimaru, openly admitting that they deserve punishment for their actions and calling out her husband for doing all this for his ambition.
- Nice Girl: Nui is a gentle and kind person. When she gave birth to Hyakkimaru and saw what happened to his body, she happily accepted him as her son. She is also shown to be protective of Dororo when she rescues him in episode 22 and tends to the wounds of the injured villagers in the episode.
- Parental Neglect: Due to her regret over what happened to Hyakkimaru, it seems she never really spent a lot of time looking after Tahōmaru.
- Together in Death: In the 2019 anime,she decides to die with her son, Tahōmaru in the burning castle falls around them.
- Unwanted Spouse: Downplayed. In the 2019 anime, shes aware her husband never love her and he only married her so she can give birth to his heir. Nuis relationship with him seems neutral after he took away her firstborn son away from her.
Voiced by: Shoya Chiba
- Ascended Extra: He ends up being one of the last people Hyakkimaru fights in the series, but in the original, he's largely a one-off. Later adaptations would give him a more important role, and the 2019 continuity pretty much uplifts him to main character status.
- Anti-Villain: He stands against Hyakkimaru because he feels only the demons can protect his people.
- Always Someone Better: Since the two met Hyakkimaru has been this to him. In episode 10 despite spending the episode preparing to kill a giant crab monster with an entire village's help, he fails with Hougo almost dying as a result and then Hyakkimaru arrives and instantly kills the monster with a single strike. Each time they fight one on one, Hyakkimaru has the advantage that slowly starts to grate on Tahōmaru.
- Ax-Crazy: He starts to lose his sanity as the show goes on growing more bloodthirsty and ruthless when he's on the hunt for Hyakkimaru.
- Blood Knight: He is way too eager to start a fight. As shown when volunteers that he should go fight for his father's land but is shot down. But as Hyakkimaru comes around he realizes that he is the cause for his land being damaged and has an unhealthy obsession of killing him.
- Broken Pedestal: He learns everything that Daigo did to Hyakkimaru in episode 12 and is very disgusted by both his parents for their actions. He still stands with his father regardless.
- Dies Differently in Adaptation: After fighting Hyakkkimaru on his home turf, he gives up his extra eyes and bleeds out in his mother's lap.
- Demonic Possession: In the final episode, Asura attempts to take over Tahōmaru's body after he lost to Hyakkimaru to finish the deal. Tahōmaru is able to resist before Hyakkimaru finishes Asura for good.
- Extra Eyes: Tahōmaru was given Hyakkimaru's eyes after he acts as a proxy for Asura.
- Eye Scream: He loses one of his eyes in episode 12 while fighting Hyakkimaru.
- Foil: He's Hyakkimaru's exact opposite. Hyakkimaru grew up with nothing, not even his body but he was raised lovingly by Jukai and trained by experience due to demons being naturally attracted to him. Tahōmaru grew up as the heir of a prosperous land with an able body but was never the main focus of his parents' love and was sheltered from a young age. As the series continue they both become more and more demonic for different reasons as Hyakkimaru's drive to regain his body causes him to refuse to think of the consequences and Tahōmaru's sympathetic reasons give way to his hatred and pride.
- The Heavy: While his father is the Big Bad, Tahomaru gets more screentime, and is Hyakkimaru's most persistent foe.
- HeelFace Turn: In the last episode after losing to Hyakkimaru but his older brother sparing his life, he relents and gives back Hyakkimaru's eyes. He even calls Hyakkimaru brother in worry for him.
- Hero Antagonist: He ultimately is trying to do what's best for his people by helping them live in prosperity, but Hyakkimaru's existence gets in the wa
- Hero-Worshipper: Episode 10 shows that he looks up to his father, Daigō thinking he's the cause for their land's current prosperity. He is, but not for the reason Tahōmaru thinks.
- Hot-Blooded: Before meeting his brother he was a very passionate and driven young man who had aspiring hopes of being the next lord. He later starts to give in to anger and let's his temper blind his reasoning.
- Hypocrite: After standing against Hyakkimaru, he calls his older brother a demon and such. It get ridiculous by episode 22 when he makes a pact with the final demon Asura, gaining Hyakkimaru's eyes thus having three eyes.
- Meaningful Name: His name 多宝丸 contains the kanji for "many treasures," which lets the audience know exactly how his father views him in comparison to Hyakkimaru.
- Motive Decay: He first fights Hyakkimaru to retain the remaining prosperity of his home but after getting beaten by him and having his pride wounded, he starts letting his anger get the best of him, eventually going so far as to act on Asura's behalf to kill Hyakkimaru and complete the unbreakable pact between Daigo and the demons..
- The Needs of the Many: Tahomaru decides to fight against Hyakkimaru despite knowing and being disgusted by what his father did to Hyakkimaru because he can't risk his country suffering.
- Reasonable Authority Figure: Episode 10 has him helping a small village in his land and working to kill the monster that was infesting their water simply because he felt it was his responsibility to protect his people.
- Secretly Selfish: He keeps saying that he needs to kill Hyakkimaru to protect his land but episode 21 makes it explicit that he mostly wants revenge for being defeated and scarred by him.
- Single Tear: He sheds a single tear after Mutsu and Hyogo's deaths.
- Super-Persistent Predator: When he obsessively tries to kill his brother due to his existence causing ruin in Daigo's land. It becomes so unhealthy that he doesn't even consider his brother even human. But as of now he accepts his brother as human and helps him kill the final demon.
- Took a Level in Jerkass: He becomes much more cold-hearted after both his mother's attempted suicide and quick defeat at Hyakkimaru's hands.
- The Unfavorite: He feels this way for both his parents as he states in episode 6. He can tell his mother loves someone else more than him, while he can tell his father values his ambition more than he values him as a person. Episode 24 reveals his current grudge is due to this. Asura calling Hyakkimaru's Daigo heir and the fact Nui didn't pay much attention to Tahōmaru growing up, made him feel like second to Hyakkimaru and that his brother was stealing everything from him.
- Together in Death: In the 2019 anime, he dies with his mother in the burning castle falls around them.
- "Well Done, Son!" Guy: Even before he found out he had an older brother, Tahōmaru was constantly trying to please his mother (who was still in mourning after Hyakkimaru was taken away).
Voiced by: Mariko Munakata
- Ambiguous Gender: He looks like a young man and yet has soft feminine voice. In episode 21, it is confirmed she's a woman dressed in men's clothing.
- An Arm and a Leg: She loses her right arm in episode 21 while fighting Hyakkimaru. She loses her left arm in episode 23 while fighting Midoro.
- Artificial Limbs: She was given Hyakkimaru's right arm after acting as Asura's proxy.
- Archer Archetype: A cool, level-headed and proficient archer. Even when offering Tahomaru advice, she stays distant.
- Canon Foreigner: She along with Hyogo never appear in the original manga; their presence serves to humanize Tahomaru a bit more.
- Dark and Troubled Past: Their parents were murdered in front of them by soldiers of the Asakura clan and they were locked up in a cage with other prisoners and left to rot. Everyone else had died by the time Daigo's soldiers got to the prison. When Daigo Kagemitsu himself meets them, Hyogo bites on his arm and Mutsu threatens him with a sharpened bone.
- Heroic Sacrifice: Attempts to sacrifice herself to Asura so that the demon will continue to uphold the pact since she's already dying of the plague anyway. This fails since the pact can only be satisfied with Hyakkimaru's body.
- Killed Off for Real: She was fatally wounded and killed by Midoro.
- Red Oni, Blue Oni: The blue to Hyogo's and Tahomaru's red. Mutsu is very focused and calm, using a weapon that requires precision and steadiness. On the other hand, Tahomaru is very passionate and Hyogo, while still mostly stoic, is more hesitant and specializes more in brute strength.
- Secretly Dying: Contracts the plague late in the series.
- Sibling Team: With Hyogo, being the long-range backup to Hyogo's melee.
- Undying Loyalty: To Tahomaru because Daigo saved them and they were raised alongside Tahomaru.
Voiced by: Kenichirou Matsuda
Hyogo is the sword man in service of Tahomaru. He is also the younger brother of Mutsu.
- An Arm and a Leg: He loses his left arm in episode 21 while fighting Hyakkimaru.
- Artificial Limbs: He was given Hyakkimaru's left arm after becoming Asura's proxy.
- Cool Sword: His main weapon he uses in battle.
- Big Little Brother: He's slightly taller than his older sibling, Mutsu, and brawnier-looking.
- Canon Foreigner: He along with Mutsu never appear in the original manga.
- Dark and Troubled Past: Hoo boy, they have. Their parents were murdered in front of them by soldiers of Asakura's clan and they were locked up in a cage with other prisoners and left to rot. Everyone else has died by the time Daigo's soldiers get to the place. When Daigo Kagemitsu himself enters the cage, Hyoga bites on his arm and Mutsu threatens him with a sharpened bone taken from one of the corpses.
- Off with His Head!: The flaming horse Midoro kills him by biting his head off.
- Red Oni, Blue Oni: Red to his brother Mutsu's blue. Hyogo is stoic and reliable, but is more prone to uncertainty and often Mutsu is the one to do the diplomatic talking. As well, Mutsu uses a bow, which requires precision and steadiness to use, while Hyogo is more about brute strength.
- Sibling Team: With Mutsu, being the melee attacker to Mutsu's sharpshooting.
- Undying Loyalty: To Tahomaru because Daigo saved them and they were raised alongside Tahomaru.
- Bitch in Sheep's Clothing: It appears as a benevolent figure but is really a monster that preys on outsiders who come to its village.
- Clingy MacGuffin: It will not leave its owner until someone knocks it out of owner's hands or destroys it.
- Evil Weapon: Has no problem controlling its owner to kill.
- Hungry Weapon: As said above, it thirsts for blood and will compel its owner to kill in order to sate that thirst.
- Meaningful Name: Its name in Japanese (似蛭) means leech-like. Fitting as it relies on its host to kill.
- More Than Mind Control: To Tanosuke. Even when he is freed from the possession, he tries to get it back so he can murder people again.
- A Head at Each End: Has another head at the end of its tail.
- Creepy Centipedes: It is a Ōmukade, a large centipede demon from Japanese folklore.
- Dark Is Evil: Due to its weakness to sunlight, it can only operate under dark areas. During the day, it counteracts this by shedding its skins to create the area of darkness around it.
- Human Sacrifice: It threatens to devour the entire village unless they periodically offer a bride for it.
- Weakened by the Light: Sunlight hurts it so it can only freely move around inside the dark smoke it exhumes.
- BFS: The sword it carries as a Buddha statue is absolutely enormous. Fortunately, its swings are very slow as a result, allowing Hyakkimaru to dodge them with ease.
- Face Stealer: Particularly grisly version in the 2019 anime as it does so by slicing an unfortunate victim's face off.
- Hoist by His Own Petard: The statue accidentally destroys itself by slamming its sword into its own face trying to hit Hyakkimaru.
- Mind over Matter: It can manipulate objects, such as the ropes around it, to a limited degree.
Voiced by: Ayano Hamaguchi
Maimai-onba was one of the twelve demons that made a contract with Daigo Kagemitsu. She became the wife to Sabame so her offspring can prosper. However, she was exposed and killed by Hyakkimaru at the river.
- Insect Queen: As the mother of her brood.
- Large and in Charge: She is significantly bigger than her children.
- Kill It with Fire: How Hyakkimaru slays her in all versions.
- Moth Menace: Her demon form is a gigantic moth.
- Mystical White Hair: She has long white hair in her human form.
- Unholy Matrimony: Actually became Sabame's wife in exchange for letting his lands prosper.
Jiromaru and SaburomaruThe Shark Demons are two huge sharks under the command of Shiranui. They were ruthless, relentless beings, which never hesitated to devour their victims after being given the command by their master to do so.
- Eye Scream: Jiromaru loses an eye from Hyakkimaru during their fight.
- Fusion Dance: Jiromaru devours Saburomarus corpse and mutates into a giant white shark demon with horns and legs.
- Good Eyes, Evil Eyes: Jiromaru's eyes turn black with yellow iris when it gets angry.
- One-Winged Angel: Jiromaru can transform into even more monstrous form, turning all white and growing legs.
- Pet the Dog: The only human they don't devour is Shiranui.
- Threatening Shark: A pair of gigantic sharks that can easily overwhelm a group of bandits.
- Fusion Dance: Once its face gets sliced in half, it devours Saburota in its last attempt to destroy Hyakkimaru.
- Mix-and-Match Critters: Has body parts of multiple animals.
- One-Winged Angel: After devouring Saburota, it grows wings within its body and its sliced half of the face is restored by the upper body of the samurai.
- Red Eyes, Take Warning: Has menacing red eyes inside its black eye holes.
- Two-Faced: As the result of Hyakkimaru's slicing its face in half, its restored form becomes this.
- Canon Foreigner: It only appears in the 2019 anime.
- Eldritch Abomination: The form it takes in the finale is of a bizarre, twisted...thing checkered with crystalline structures.
- Final Boss: He acts as this in the 2019 anime due to being the last demon standing and having Hyakkimaru's eyes and arms. Adding to the fact the only reason Hyakkimaru is still alive is because Asura failed to take his head.
- Fusion Dance: Of a sort as it bequeaths Hyakkimaru's arms to Hyogo and Mutsu while giving his eyes to Tahomaru.
Voiced by: Naoya Uchida
- Abusive Dad: Even after sacrificing Hyakkimaru, he still treats him with contempt.
- All for Nothing: By the end of the series due to Daigo's contract with the demons being nullified, everything he worked for is now gone. His lands are devastated, his people hate him, his army suffered heavy losses, and his wife and heir are dead. Hyakkimaru doesn't even give him the satisfaction of death, instead telling him to live on as a human. To rub it in further, Daigo admits prosperity might have come naturally had he been patient.
- Archnemesis Dad: He offered up "anything" for power, in spite of being told that making a pact with demons was a bad idea. And once he learns that Hyakkimaru is alive, he becomes dedicated to killing him.
- Ambition Is Evil: On the one hand, he was looking out for his lands and people...but on the other hand, he only really did it to boost his own prestige.
- Big Bad: He's the main antagonist of the series.
- Bitch in Sheep's Clothing: He presents himself as a kind and wise lord to his people thus why he has a 100% Adoration Rating to his land even lying that the current prosperity is because he slayed the demons instead of making a deal with them. But underneath all that is a narcissist that cares more about his ambitions than others.
- Cruel Mercy: Hyakkimaru spares his life and tells him to live as a human. However, considering that Daigo's army had been decimated by the forces of Asakura, his lands devastated because of the demons' blessing being forfeit, as well as his wife and heir dead, Daigo now has nothing.
- Deal with the Devil: The show started when Daigo made a deal with the 12 demons to save his land.
- Death Seeker: In Episode 24 after Tahomaru and Nui are gone, his land ravaged by war and poor weather conditions, he awaits Hyakkimaru in the Hall of Demons. He says things meant to obviously enrage his son such as he will do another deal or he should have strangled Hyakkimaru as a baby as he leaves a sword next to Hyakkimaru. He's shocked that Hyakkimaru spared him.
- Establishing Character Moment: This comes when he finds out that the 12 demons took his firstborn son's body parts as payment for their service. Instead of feeling pity for their son's predicament, he expresses joy knowing the demons agreed to his deal and starts laughing maniacally, cementing just how selfish he is.
- Hate Sink: The story more or less does a good job at showing what an irredeemable scumbag Daigo is. He is responsible for his son Hyakkimaru's predicament, still treats him with contempt and has no doubts or regrets about the deal, in contrast to Nui and Tahōmaru.
- He-Man Woman Hater: He looks down on women, believing they are nothing more than a tool to give birth to offspring and they should be obedient with no free will of their own. He doesnt love his wife at all and he only married her so she can produce a son for him.
- I Have No Son!: Only considers Tahōmaru as his son and heir, and Hyakkimaru as a menace.
- Lack of Empathy: It takes an extremely cold-blooded person to sacrifice their own children out of selfish greed.
- Laser-Guided Karma: He sacrificed Hyakkimaru to the demons to save his starving land and in the last episode, after Hyakkimaru killed all the demons, his land is once again struggling but with the added bonus that he lost Nui and Tahōmaru. Now he's left to live with the realization that if he wasn't so hasty, the prosperity that he wanted could have come from Hyakkimaru's rule.
- Marriage of Convenience: He doesnt love Nui and he only married her so she produce a heir for him.
- Narcissist: In episode 23, he refuses to back down as his deal with the demons starts to backfire as he can't accept that he was wrong.
- Never My Fault: Subverted in Episode 24 when he and Hyakkimaru meet. At the start, he refuses to say his deal was wrong and that the only fault was that he didn't kill Hyakkimaru as a baby right away. But after Hyakkimaru spares him, he's left to wonder that if he had never made that deal and let Hyakkimaru rule, maybe the prosperity he wanted would have come naturally.
- Non-Action Big Bad: Daigo's deal set the series in motion but he rarely confronts Hyakkimaru directly. Most of the time, it's the demons or Tahōmaru that fights Hyakkimaru as he's busy dealing with other things.
- Powered by a Forsaken Child: His rise to the top is the result of sacrificing his first baby son to demons.
- Secretly Selfish: While he'll defend his deal was the only way to save his land, Nui and Tahomaru can see that it was at least partly out of his own ambition.
- The Sociopath: He is more than happy to sacrifice his own son for power, treats his own people like crap and overall shows zero remorse for his actions.
- Tears of Blood: In the last episode, the blood from his head wounds fall into his eyes as he cries after finally realizing his mistake.
- Villain with Good Publicity: In the 2019 version, he's loved by his people for making their lands so rich and prosperous.
- "X" Marks the Hero: Subverted. The cross mark on his forehead was given to him by the demons.
Voiced by: Hiroki Takahashi
- Blood Knight: He's a bloodthirsty killer who enjoys killing innocent lives under the influence of the demon sword, Nihil.
- Death Seeker: He wants to be killed by someone stronger than him since the sins he committed five year ago under the influence of Nihil, killing soldiers and innocent lives, can't be forgiven. He got his wish and he ends up being killed by Hyakkimaru.
- Disease Bleach: His hair was originally black until after he was corrupted by the demon sword, Nihil, his hair turned completely white.
- Even Evil Has Loved Ones: Despite being a serial killer, the only people he doesn't kill with or without the influence of Nihil are his family. In the 2019 anime, he decides not to kill his sister since she is the only family he has left and folds one last paper crane for her before setting off to retrieve the demon sword.
- Sanity Slippage: It is due to wielding the demon sword, Nihil for five years, he becomes crazy addicted to killing innocent people in order to please his weapon's blood-lust. Even after being freed from the demon sword temporarily by Hyakkimaru, he still wants to wield Nihil instead of reconciling his sister and going back home together. Not even his own sister can snap him out of his obsession.
Voiced by: Setsuji Satoh
- Chronic Backstabbing Disorder: He betrayed Dororo's father, Hibukuro by crippling him and sided with the authorities.
- Desecrating the Dead: He really shows how despicable he can be when he reveals he found half of Hibukuro's treasure map by digging up Ojiya's grave.
- Dies Wide Open: He dies, with his eyes wide open after he saw the treasure one last time. Dororo gently closes them after he saved her life from Shiranui's suicide attack.
- Even Evil Has Standards: He's horrified that Shiranui fed an innocent village to his sharks and feels a little bit bad after stripping Dororo, but only because she was actually a girl. And later on regrets digging up Ojiya's grave for her half of the map.
- Father to His Men: Part of the reason he beat Shiranui to near death is because Shiranui's actions caused the death of half of his men.
- Greed: He's very focused on money and will betray others to get it. This is one of the reasons why he betrayed Dororo's father, Hibukuro in the first place.
- Hate Sink: Everything about him that Itachi is a horrible person. First, he betrayed his commander in order to be on the winning side instead of by side until the bitter end. After years passed, he now kidnaps Dororo just to used her to search for her parent's hidden treasure and forcefully strip Dororo naked to find the other half of the map.
- Heroic Sacrifice: He used the last of his strength to shield Dororo from a landslide caused by Shiranui.
- Laser-Guided Karma: He betrayed Hibukuro by leading him to a trap by the samurai, years later Itachi was betrayed by becoming bait and left to die by those same samurai.
- Last Request: In the 2019 anime, he asks Dororo to take him to see the treasure before he succumbs to his wounds.
- Kick the Son of a Bitch: He and his men brutally beat Shiranui, who by all means is a psychopath that fed innocent people to sharks.
- Morality Pet: He is generally fond of Dororo and tends to show the better parts of himself in his interactions with the kid.
Voiced by: Ayumi Fujimura
Okaka was a young lady who lived in a small cottage which Dororo and Hyakkimaru encountered along their journey. She initially appeared to be a kind, compassionate individual, allowing the two to stay in her cottage for shelter. However, she was, in truth, the spirit of a Buddha Statue carver who lived a very long time ago. She was resurrected by a vengeful spirit that resides within the stone Fudo Buddha statue which she carved in her previous life, to find the perfect face for it.
- Gender Bender: She was originally a man when she was alive until the spirit of a Buddha resurrected her as a spirit and turn her into a woman.
- HeelFace Door-Slam: As she was about to let Hyakkimaru go after a change of heart thanks to Dororo, she was killed by by the Fudo statue with the blade it carried.
- Identity Impersonator: She is capable of shape-shifting her face to impersonate other people.
- Logical Weakness: Her power to imitate faces hits a snag when confronting Hyakkimaru as he's blind and has never seen anyone's face, so she has nothing to draw upon.
- Wouldn't Hurt a Child: She doesn't kill children since she spares Dororo's life for being used as a sacrifice to give Fudo statue a face because Dororo's face is too young and innocent.
Voiced by: Koji Yusa
Sabame is the landlord of a mountain village that appeared in Episode 14 and 15. In the 2019 adaptation, he willingly formed the contract with the demoness Maimai-onba, providing her brood with food and shelter in exchange for their protection of his mountain village. He is the true murder of Jishō Nun after being exposed by her for kept a secret for the moth demonness.
- Adaptational Villainy: In the original, he was a victim of hypnosis by Maimai-onba and had little to no control over his own actions. In contrast, the 2019 anime made him a willing participant in razing the temple and offering orphans to the moth demoness and her brood.
- Ambiguously Evil: Because his deal with Maimai-onba was made with a genuine desire to protect his land and people, Hyakkimaru has difficulty determining if hes evil or not as only the very edges of his soul have flecks of red in them.
- Blatant Lies: In episode 14 he says Jishō Nun was a cruel woman who abused the orphans she looked after and a Bolt of Divine Retribution killed her and the kids. Dororo and Hyakkimaru realize he's lying right away, as they found oil at the burnt temple. He actually killed her so he could feed her orphans to Maimai-onba's children.
- Deal with the Devil: He made a deal with one of the same demons that Daigo also made a deal with to protect his land.
- Death by Adaptation: He's alive in the manga, but in the 2019 anime, he kills himself after the Maimai-onba's children destroyed the village.
- Despair Event Horizon: After his village was burned to the ground and his villagers started fighting among themselves.
- Driven to Suicide: In the 2019 anime, he commits suicide after his village and their rice storage are destroyed.
- Fish Eyes: Has a creepy, unfocused bug-eyed stare, which Dororo comments on.
- Foil: Acts as one for Daigo as they both made a Deal with the Devil to make their land prosper. The only real difference is Sabame is more sincere in his desire to protect his land while everyone can tell that Daigo did so partly out of ambition.
- I Did What I Had to Do: How he justifies his deal, regular murder of travelers and murder of Jishō Nun and the orphans she looked after. His village is everything to him.
- Laser-Guided Karma: He burned down Jishō Nun's temple to feed Maimai-onba's children to protect his village. Years later those same children accidentally burn down his village.
- Would Harm A Child: He's perfectly fine feeding Dororo and the orphans Jishō Nun looked after to Maimai-onba's children.
Voiced by: Ryuichi Kijima
- Adaptational Attractiveness: Downplayed. He is drawn slightly more attractively than his manga counterpart, but the though he's now missing his right arm, some of his teeth, and has scars on most of his body.
- An Arm and a Leg: According to him, Shiranui fed his right arm to his two shark demons, Saburomaru and Jiromaru, in order to tame them to him.
- Covered with Scars: In the 2019 anime, he has several scars on his chest, arm and legs. He has large flame-like scar on his right side where his right arm used to be.
- Dark and Troubled Past: In the manga, Shiranui mentions his parents died in the war when he was young. But in the 2019 adaptation, he lived alone on the desert island with his mother until she died of starvation. This is one of the reasons why he resent humanity for being weak and worthless.
- Dies Differently in Adaptation: He was killed by Hyakkimaru in the manga, but in the 2019 anime, he commits suicide by setting off the bombs to creating a landslide attempt to kill everyone. Shiranui's lifeless corpse was last seen on shore.
- Disabled in the Adaptation: In the original manga, he was able-bodied, while in the 2019 anime he fed his right arm to the starving two shark demons and he doesn't regret it.
- Even Evil Has Loved Ones: He maybe a psychopath, but he really loves and cares for Jiromaru and Saburomaru deeply. He thinks of them as his own family. Shiranui becomes devastated after he found Saburomaru's corpse after Itachi and his men killed him.
- Eviler Than Thou: Itachi's a piece of work but even he comes off as reasonable compared to Shiranui.
- I'm a Humanitarian: In the 2019 anime, it's implies he's cannibal because one of the demon sharks gave him a severe arm, but he says he will eat later.
- Misanthrope Supreme: In the 2019 anime, he hates humanity and thinks of humans nothing more than demon food to feed to his two demon sharks, Jiromaru and Saburomaru.
- Obviously Evil: Between the deranged look in his eyes, his missing arm and being covered with scars, Dororo can immediately tell that Shiranui is bad news.
- Parental Abandonment: In the 2019 anime, his mother died of starvation when he was a child.
- Roaring Rampage of Revenge: After Itachi and his men killed Saburomaru, he orders his remaining shark demon, Jiromaru to kill them all.
- Ungrateful Bastard: He orders Jiromaru to kill Dororo, even though the latter spared him from being killed by Itachi and his men.
- Would Harm A Child: He has no problem to feed babies and children to his two shark demons. He didn't hesitant to order Jiromaru to kill Dororo even though he spare his life from Itachi and his men killing him.
Voiced by: Yuuichi Nakamura
A man whom Dororo and Hyakkimaru encounters in the mountain during Episode 20. Initially appearing helpful to the duo as he leads them to the place in the mountain where Nue frequents, he reveals his intention to feed them to the demon once Hyakkimaru starts fighting Nue. In the past, Nue devoured his mother right in front of him and he ran for his life instead of protecting her. As it effortlessly crushed his fellow villagers who offered to help him get revenge, he instead convinced himself that there is nothing one can do against such monster and submitted himself to it, luring travelers into its territory so it can devour them.
- Curtains Match the Window: Both his hair and eyes are brown.
- Dirty Coward: Unwilling to admit his cowardice, he led other people to their deaths in order to persuade himself that no man can fight off Nue.
- Disease Bleach: His hair was originally brown until he feed himself to a Nue and his hair turned white.
- Fusion Dance: He feeds himself to Nue in a last bid to destroy Hyakkimaru. Doubles as Driven to Suicide.
- Scars Are Forever: He has a scar marks on his chest after being slashed by a Nue.
- Used to Be a Sweet Kid: He was once a dutiful son who carried his mother over mountain to see a doctor and hoped to provide better life for her with his sword.
- Villainous Breakdown: As Hyakkimaru gains the upper hand against Nue, he breaks down as his reasoning for abandoning his mother and others to Nue had become invalidated.
Voiced by: Kouhei Amasaki
Kaname is formerly Jukai's disciple. He left his master after knowing that Jukai used to work for Lord Shiba.
- Artificial Limbs: He had an prosthetic leg given by Jukai until he found out about his past. After that, he discard his prosthetic leg and replace it with a wooden walking stick.
- Canon Foreigner: He's one of the characters who never appear in the original manga and he only appears in the 2019 version.
- You Killed My Father: After he found about Jukai's history, he develops a strong hatred toward him and wanted revenge on him for killing his father. However, he couldn't bring himself to kill him so instead he left him.
- What Happened to the Mouse?: It's unknown what happened to him after he left Jukai, but it's heavily implied he told Jukai's customers about his past.
Voiced by: Marina Inoue
- Adaptational Ugliness: Subverted. Osushi is still attractive in the 2019 anime, but she has short hair because she had to cut her long hair she used to had five years ago in order to survive as a peddler.
- Ain't Too Proud to Beg: She begged Hyakkimaru to spare her brother's life even though he can't be saved or reasoning with, but he doesn't listen her and kills him.
- Boyish Short Hair: In the 2019 anime, she has short hair.
- Memento MacGuffin: In the 2019 anime, She kept an origami crane made by her brother, Tanosuke since the day he was sent to war five years ago. However, after her brother's death, this ends up as a Tragic Keepsake.
Voiced by: Nana Mizuki
- Cool Big Sis: The children that she cares for view her as a very loving big sister.
- Cope by Creating: She sings so that she doesn't feel sadness even when she's selling her body.
- Defiled Forever: Mio reveals that she feels dirty for selling her body every night, even thinking her soul is dirty. Shortly after Mio voices her concerns, however, the scene cuts to Biwa-hoshi's perspective showing her soul to be spotless. Later, Dororo reacts very poorly when Mio calls his mother "admirable" for never taking up sex work - a decision which led to her starving to death - and counters that Mio is just as (if not more) admirable for doing what most wouldn't to survive.
- Love at First Note: Her songs are very beautiful and Hyakkimaru first meets her by following the sound of her singing. Mio's songs are the only sounds that can calm Hyakkimaru after getting his ears back.
- Hooker with a Heart of Gold: To get money to sustain herself and the children she takes care of, she sells herself to soldiers at night as a job.
- Not What It Looks Like: She sells herself to multiple enemy camps, which leads to one of them thinking she's a spy.
- Nice Girl: She's a very sweet and kind person. When Hyakkimaru is attracted to her singing and follows the sound to her, she realizes that he's blind, but doesn't act in fear and is very friendly towards him in their first meeting. She also decides to let him, Dororo, and Biwa-Hoshi stay in her home.
- Stuffed into the Fridge: She's murdered by soldiers who mistake her for a spy, which triggers Hyakkimaru into an Unstopabble Rage.
- Too Good for This Sinful Earth: Too good indeed... She's one of the most kind-hearted and selfless characters in the story. And her kindness is repaid with her being killed.
- Tragic Dream: She wanted to grow a large rice paddy so that she and the children would no longer starve. And she had just purchased seeds the day they were all killed.
Hibukuro and Ojiya
Voiced by: Kenta Miyake (Hibukuro), Ayumi Fujimura (Ojiya)
- Ain't Too Proud to Beg: Ojiya will do anything to keep Dororo alive, even beg Itachi for help.
- Blade on a Stick: Hibukuro's personal weapon in the 2019 adaptation, so much so that a samurai actually recognized him because of the weapon.
- Cycle of Revenge: Hibukuro created his bandit group out of revenge from being pushed around by the samurai and was later killed by one of his past victims of his bandit group.
- Good Parents: They both loved Dororo and despite being down on their luck later on, they focused on keeping him alive.
- It's Personal: Hibukuro deeply loathed samurai, creating a bandit group made solely of disgruntled farmers just to raid them.
- Posthumous Character: Both of them are dead by the start of the story and we only see them by flashbacks.
- Robbing the Dead: After being betrayed by Itachi, Hibukuro and Ojiya are forced to loot corpses on battlefields for food to survive.
- Taking You with Me: After Hibukuro is fatally stabbed, he grabs his murderer and gives him a bear hug so the blade pierces him too.
- Treasure Map: Hibukuro tattoo his wifes back the first half of the map before his death and the second half on Dororo's back on Ojiya's request.
Voiced by: Yume Miyamoto
She is the daughter of Munetsuna and also the second love interest of Hyakkimaru after Mio.
- Canon Foreigner: She's one of the characters who only appear in the 2019 version.
- Happily Married: She marries a young man from her village after Amanojaku was sealed away again.
- Love at First Sight: She fell in love at Hyyakimaru at first sight after Hyyakimaru touch her forehead with his. She thought it was a sign of affection even though they just met.
- Second Love: Okowa is Hyakkimaru's second love interest after Mio's death. However, this ends up as a Romantic False Lead since it was a misunderstanding caused by an Amanojaku that makes everyone speaking the opposites of what they mean. It also means that Hyakkimaru wasn't into her. She takes this in stride, however.
Voiced by: Kazuhiro Yamaji
Munetsuna is the father of Okowa and is known as the best swordmaker in the land. He is the one who sharpened and fixed up Hyakkimaru's arm blades. Although he makes a living by making swords, he has expressed discontent with the products he has made and wishes that he would make a sword for peace and not bloodshed.
Voiced by: Tamura KintoHe was the spirit of a traveler who became the first victim of Bandai.
- Iconic Item: He carries a pilgrim's bell on his right hand.
Voiced by: Harumi UedaShe is the spirit of a deceased nun and a minor character who once ran an orphanage in the mountains. Some time ago, She, along with the orphans and the orphanage, burned down in a fire caused by Sabame after discovering that the landlord had made a pact with Maimai-onba to keep the land prosperous by sacrificing travelers and animals to feed the demoness and her offspring.
Voiced by: Yoko KaidaA ghoul taking the form of a giant spider with the ability to shapeshift into a beautiful woman. Hyakkimaru attacks her, but she manages to escape and ends up falling in love with Yajiro, a human from the neighboring village. Unlike other ghouls, she does not kill humans, instead nonlethally feeding on their spiritual energy. She is also known as "Ohagi", the name Yajiro gave her.
- All Webbed Up: She is called the Jorogumo Silk Spider for a good reason.
- Dark Is Not Evil: She is a ghoul with the appearance of a horrific, monstrous spider, but she is also one of the most reasonable characters in the series and genuinely nicer than many humans.
- Defrosting Ice Queen: She initially sees Yajiro as a snack and treats him with haughtiness and arrogance, but as he continues to care for her, starts developing genuine feelings towards him and treating him with more kindness, eventually falling in love with him.
- Earn Your Happy Ending: Thanks to her connection with Yajiro, she manages to escape the despotically ruled village with him and is spared by Hyakkimaru, who realizes she is no longer a threat.
- Emotion Eater: It's implied she gains the most energy from those who are in the grips of lust, hence her name, translating to "prostitute spider".
- Energy Absorption: Instead of eating people, she eats men's spiritual energy, leaving them temporarily tired and drained, but alive.
- Foreshadowing: Perceptive members of the audience may realize that something is up with her when she leaves Hyakkimaru completely incapacitated in her webs... then proceeds to flee instead of taking the opportunity to devour both him and Dororo.
- Hypercompetent Sidekick: Despite being a mere ghoul rather than a full demon, she gives Hyakkimaru a run for his money thanks to her webs. Had she been the murderous type of ghoul, she could have killed both Hyakkimaru and Dororo with little trouble while the former was All Webbed Up, thankfully, she is not overtly hostile to humanity.
- Pragmatic Villainy: How she rationalizes feeding on humans' spiritual energy instead of their flesh:"Humans are precious prey."
- Rescue Romance: She falls in love with Yajiro after he starts nursing her back to health following Hyakkimaru's attempt to kill her.
- Spider People: Her true form has a humanoid upper body growing out of a spider abdomen.
- Token Heroic Orc: Despite being a ghoul with a red soul, she does not kill humans at all and is capable of compassion and even love. This makes her the only ghoul in the series who is eventually spared by Hyakkimaru.
- Tsundere: Towards Yajiro. She first speaks to him in a very arrogant and condescending manner, but warms up to him quickly.
Voiced by: Ikue OtaniThey are the benevolent spirit vessel that houses the deceased children who once lived in an orphanage in the mountains. Some time ago, they, along with the nun, and the orphanage itself, burned down in a fire by Sabame after they discovered the landlord made a pact with Maimai-onba to keep the land prosperous by sacrificing people to feed the demoness and her offspring. Since then, the orphans who were sacrificed came together and created this spiritual form.
- Adaptational Heroism: In the 1969 manga and anime, she was one of the 48 Demons that took Hyakkimaru's body parts, but in the 2019 anime, she is a revived horse that decides to help Hyakkimaru fight against Daigo's men.
- Back from the Dead: She was revived by possessed armour, and becomes a powerful flaming steed to assist Hyakkimaru take his revenge.
- Black Eyes of Crazy: Of the "yellow iris, black sclera" variant (previously she had innocent black eyes). She's not insane, but monumentally pissed off.
- Cool Horse: Can devastate an entire army all on her own.
- Dark Is Not Evil: She may be a demonic horse revived by the unresolved grudges of spirits, but she's only attacking the soldiers of Daigo's army. It's also clear she has a heart as despite being mortally wounded by Hyogo and Mutsu, her last act is to lovingly nuzzle her foal before dying.
- Hellish Horse: An heroic example in the 2019 anime.
- Hoist by His Own Petard: She was used as a suicide bomb to take out Hyakkimaru. All it accomplished was giving him a badass demon horse that proceeds to tear through Daigo's army.
- Killed Off for Real: She was killed by Mutsu and Hyogo.
- Laser-Guided Karma: The one inflicting this as she burns to death the man who blew her up with bombs.
- Mama Bear: Her source of anger is being taken away from her child.
- Playing with Fire: She can breath fire and create a fiery tornado.
- Undying Loyalty: To Hyakkimaru.
- Why Am I Ticking?: She was loaded with explosives by Daigo's men and sent charging at Hyakkimaru in an attempt to kill him. She died in the explosion, but Came Back Strong.