Beware of unmarked spoilers.
One of the leading Fallen Houses, the Devils are primarily centered in the Cosmodrome of Old Russia. The loss of Solkis, the Devil's Kell, in the aftermath of the Battle of Twilight Gap weakened the Devils. Now they scavenge the Cosmodrome for buried secrets in an effort to gain an edge over humanity and the other houses.
Riksis, Devil Archon
The Archon of the House of Devils, and the first boss the player encounters.
- Badass Preacher: As an Archon, he kicks copious amounts of ass.
- Battle Trophy: He is noted to collect the skulls of dead Guardians, but whether he keeps them for himself or presents them to a Prime is unknown.
- King Mook: A super Captain, and twice your size.
- Warm-Up Boss: The first proper boss the player faces.
Sepiks Prime / Sepiks Perfected
The boss of the Devil's Lair Strike, the exalted Servitor of the Fallen House of Devils, a crucial strategic target to break the will of the Fallen who most directly threaten the City. After the House of Devils discover SIVA, Sepiks is returned to life and leads the Devils in assaulting Felweinter's Peak.
- Back from the Dead: The House of Devils use SIVA to return Sepiks Prime to life and stronger than before as Sepiks Perfected.
- Barrier Warrior: Becomes this as Sepiks Perfected, as periodically through the fight, it gains an elemental shield that can only be damaged by a scorch cannon of the matching element.
- Flunky Boss: Not as bad as the other bosses in the game, as it only summons them in a small wave, being usually 5-7 enemies at once, with the waves having long pauses in between.
- Keystone Army: The keystone for the House of Devils, as it manages their entire supply of life-giving Ether.
- King Mook: A gigantic and extremely durable version of the normal Sevitors. Compared to other Servitors, it can do a powerful drain that can quickly kill a Guardian, and shoots bigger and more damaging versions of a regular Servitor's Void Cannon.
- Sinister Geometry: Like all Servitors, Sepiks Prime is an enormous black sphere covered in purple lightning. Unlike most Servitors, it is extremely powerful. And spiky.
A Shank modified to be able to crack the Warmind Rasputin's defenses and the boss of the "Fallen S.A.B.E.R." Strike.
- Awesome Mc Coolname: The first named Shank, and it does not disappoint in its machine connotation.
- Badass Automaton: Let us repeat: this is a machine that can bypass Rasputin's network and make the entire bunker its playground.
- King Mook: It's a gigantic Shank. Yes, you read that right.
- Pun: A shank is a sort of makeshift knife. Naturally, their super-sized, armed-to-the-teeth cousin is named after a big sword.
- Super Prototype: Multiple Heavy Shanks have appeared in Destiny and its sequel, including S.A.B.E.R.-6, but none of them have been as powerful.
- Transforming Mecha: At several health thresholds, the boss changes its configuration, starting out with a Solar cannon akin to a Vandal wire rifle, then alternating between it and two more modes; a Void-based chassis with dual miniguns and an Arc-based close-range taser.
- Weak, but Skilled: The S.A.B.E.R.-2 by itself is fairly average as far as bosses go, its health dropping easily from high-end content weapons and possessing few powerful weapons despite multiple configurations. However, on top of summoning multiple flunkies to hinder you, it abuses the hell out of the boss arena, setting out multiple lightning traps.
Iliksis, Light Stalker
A Devils captain who leads an assault on Bannerfall in an attempt to breach the walls of the Last City.
- For Want of a Nail: The Young Wolf was just trying to find some blueprints at Bannerfall; had they not been there, Iliksis would have succeeded in bringing down part of the city wall and invaded, causing who knows what kind of damage and casualties.
- Giant Space Flea from Nowhere: His sudden appearance turns a peaceful investigation mission into an extremely difficult fight that threatens the safety of the Last City. There were no mentions of him or his forces in any missions or lore prior to his assault, making his appearance completely unexpected.
- King Mook: He is a giant Fallen Captain, and is easily one of the largest enemies in the game.
Keksis, the Betrayed
Eramis, the Shipstealer
A Baroness of the House of Devils, known for stealing the ships of others and is plotting Fallen reunification under the Devil banner. During the events of Forsaken, she is among the many inmates of the Prison of Elders who take advantage of Variks's orchestrated prison outbreak, fleeing to parts unknown. The Praxic Order catch wind of her activities, designating her as VIP#2029 and branding her as a potential threat to the City.
- Space Pirate: The Praxic Order's report describes her as the classical Fallen pirate of the old ways, being vicious, uncompromising and extremely cunning. This ironically makes her the most likely candidate to rally the Fallen, unlike Variks, Mithrax and Fikrul, all of which seek to do the same thing through fairly esoteric means.
- The Unseen: We don't encounter her during Joker's Wild, but her forces are scavenging the ruins of the Old Tower to get their hands on a piece of SIVA technology that could help them rebuild the House of Devils. Mithrax makes a point of assigning you to recover the Outbreak Perfected before the Devils do.
The Devil Splicers
The Devil Splicers are Fallen Splicers of the House of Devils who uncovered SIVA and began using it to augment their bodies.
- A God Am I: The discovery of SIVA caused an ideological split among the House of Devils Splicers. While the more traditional Splicers saw SIVA as another technology to be worshipped, a radical faction, lead by Aksis, thought that SIVA was a means to become "machine-gods". Eventually, Aksis' Devil Splicers won the split and not only took over the Splicers, but took over the leadership of the House of Devils itself.
- Body Horror: Most of their forces sport cobbled-together prosthetics. The Dregs in particular now walk on peg legs instead of their normal legs, and what appears to be a Kell is almost completely mechanical.
- Bullet Proof Helmet: Splicer Vandals wear a helmet that renders them resistant headshots. To score critical hits, you have to aim for the throat instead.
- Deus Est Machina: While the Fallen were already known for their worship of technology, the Devil Splicers take it further with their use of SIVA, allowing them to become the machine gods they so worship, with no regard to how much it changes them.
- Ninja Pirate Robot Zombie: Mutant Cyborg Space Pirates, to be exact.
- Mad Scientist: Described as "body hackers and bioengineers who fuse metal and flesh". And with how they willingly apply prosthetics onto themselves, it's clear they're incredibly fanatical, even for the Fallen.
- More Dakka: Unlike their less insane brothers, Devil Splicers favor sheer volume of fire over accuracy. Their Shock Rifles trade away homing rounds for faster automatic fire, Shock Pistols move in a zigzag pattern, Wire Rifles fire in bursts, and Servitors go for a full-on onslaught of erratic crimson plasma. Anymore, and they'll quickly turn Destiny in to the FPS equivalent of a Bullet Hell game.
- Red and Black and Evil All Over: Though their clothes are white, their armor and fur extensions are black and crimson respectively.
- Taking You with Me: Nearly all Splicers killed via headshot have a chance to release a cloud of SIVA drones that'll seek you out, similar to a Taken Centurion's Axion Dart.
- Turns Red: Vandals who take a beating will gain a "berserk" state similar to Hive Knights, recovering some health and charging you with melee.
Aksis, Archon Prime
Once a disgraced Splicer, Aksis is the leader of the radical faction of the Devil Splicers and has proclaimed himself Archon of the House of Devils. Having fused himself with SIVA, he is now more machine than Eliksni.
- Arc Villain: He's the ones pulling the Devil Splicers strings from the shadows, causing them to stir trouble in the Plaguelands during Rise of Iron. Unlike Oryx and Skolas, he doesn't appear in the expansion's main story (indeed, he doesn't even get mentioned until after you beat it), and you get to off him in a climactic raid that ends the expansion's story.
- Ascend to a Higher Plane of Existence: The Grimoire compares his SIVA-ification as something of an uplifted state, being the greatest result of the Devil Splicers' research.
- Authority Equals Asskicking: By the events of Rise of Iron, Aksis rallied most of the House of Devils under his command in order to further the researches on SIVA technology, and ends up transforming himself into the single most powerful Fallen in the present setting with the help of SIVA.
- Battle Theme Music: Aksis's second and final encounter uses parts of "Eyes Up", swapping themes depending on the phase of the fight. It's a grand orchestral piece not unlike Oryx, which in turn ups the epicness of the encounter.
- Damage-Sponge Boss: Sports well over 10 million HP, though the boss fight provides you with a variety of tools to deal considerable damage to him (elemental cannons and the opportunity to recharge your super abilities instantly come to mind).
- Death-or-Glory Attack: Once he drops to 10% of his health, he'll teleport back to his default position and try to cause a Total Party Wipe on you by blowing himself up.
- Final Boss: All expansions considered note , Aksis is the last antagonist fought in Destiny, and is found at the end of the "Wrath of the Machine" raid; the final raid introduced in the game. note
- From Nobody to Nightmare: Originally a disgraced Splicer in the House of Devils, he managed to lead a radical faction to overtake not only the Splicers, but the entire House of Devils.
- High Priest: As Archon, he's the leader of the House of Devils priesthood.
- Mage Marksman: The Magic Gunman variety, as Aksis wields a massive SIVA-fueled cannon to bombard enemy Guardians with, while also being able to oversaturate the SIVA in his boss area, creating a large explosion that causes a Total Party Wipe unless standing on a safe platform. He executes the latter technique by holding his hand in the air, reminiscent of a magic incantation.
- Orcus on His Throne: While he is the leader of the Fallen faction that provokes the SIVA crisis seen in Rise of Iron, Aksis stays put in the deepest reaches of the Plaguelands, awaiting for offerings from other Fallen like the machine god he's become.
- Puzzle Boss: Much like the other raid bosses, Aksis is not easily dispatched like Strike bosses, and needs a considerable amount of coordination to beat. Disabling his invincibility barrier to directly damage him is only possible by throwing bombs that are dropped by Servitors that are vulnerable to a given elemental cannon, which are in turn carried by Splicer Captains that will mercilessly bombard you with them. Making Aksis vulnerable is one thing, but then you have to pin him down as he tries to teleport around to recover his barrier. That, and the ability to stun him is given randomly to your fireteam, ensuring that everyone needs to pull their weight in the fight.
- Spider Limbs: Rather than regular legs like most Splicers, Aksis connects his upper body to massive spider legs which he walks around on.
- Teleport Spam: During the beginning of his final phase, he blinks from one side of the area to another, before returning to the centre, all while bombarding Guardians with his cannon and SIVA swarms. As soon as his barrier gets damaged by SIVA charges, he will try to teleport around the four corners of the boss arena, and will need to be stunned to prevent him from releasing SIVA mites which cause a Total Party Wipe.
Vosik, the Archpriest
Aksis' lieutenant, and the first boss of the Wrath of the Machine raid.
- Arm Cannon: Taking a cue from Taniks, one of Vosik's arms has been replaced with a Scorch Cannon.
- The Dragon: Explicitly referred to as "Aksis' second-in-command" in his Grimoire card.
- Dynamic Entry: He starts attacking you as early as the very beginning of the raid, even before officially entering the Splicers' lair. He can also kill you if you so much stand on the spot he spawns in both encounters.
- Puzzle Boss: Both of his encounters qualify.
- The very beginning of the raid requires your fireteam to charge up three foundries that will eventually produce SIVA charges to throw at Vosik and deplete his shield, rendering him vulnerable to damage until he flees from the battlefield.
- The second encounter plays similar to the first one, except you will need to throw SIVA charges simultaneously to maximize damage on his shield, and shoot at one TV panel to avoid a Total Party Wipe.
- Sinister Minister: As a Splicer, his job is a combination of priest and scientist.
Kovik, Splicer Priest
A Splicer high priest responsible for much of the Devil Splicers' SIVA upgrades. Now he is collecting Hive specimens for even more nefarious purposes.
- Beam Spam: As a result of his experiments, his weapon is now a full-on beam cannon that's powerful enough to melt players in seconds even without an elemental damage modifier.
- Eye Scream: Has ripped out an ogre's eye and is using it as a weapon.
- Flunky Boss: A special case, in that he's accompanied by the ogre he's been experimenting on. Throughout the fight, it'll try to encroach upon your team and smash them. Oh, and it's invincible to all damage, so the best you can do is just keep its attention while your team handles Kovik.
- Mad Scientist: Par for the course for a Splicer, but Shiro-4 notes that even for them Kovik is an extreme lunatic due to his experiments on the Hive with SIVA.
- Sinister Minister: As a Splicer, he is a combination of priest and scientist. It was his research and teachings that led the Devil Splicers into upgrading themselves with SIVA.
Meksis, Siege Engineer
A Splicer Captain overseeing the Siege Engine in Wrath of the Machine.