Andy from Bomango. While he's Gogo's friend, he isn't afraid to call out her on her behavior or tell her that she needs to take a bath. Gogo is usually unaffected by this. But after Gogo says to Andy that she'll let him gawk at her as a birthday gift, he tells her that she isn't as good-looking as she thinks. She spends some time wondering why he'd say that, only to realize she's too big (read: muscular) and not thin enough.
Electric Wonderland did this on the first page of "Valentine's Day Massacre". After Trawn and NJ read a comic from Shroomy, Trawn tells Shroomy that it was a nice try, but not what she was looking for. NJ, who had already scolded Shroomy for not having a clever enough joke, adds, "Also, it wasn't a nice try!"
And then there is the much more extreme example between Raven and Pandora, in the Sister 3 arc. Raven remarks soon afterwards that brutal honesty is the only real way to get her to listen to him, though he clearly feels guilty about what he said.
Girls with Slingshots: Zach picks up Hazel from a visit to a nurse. He's teasing her about her injury — "What'd you do? Fall on a fencepost?" — when Hazel snaps and snarls, "I spent the whole weekend pleasuring myself because my boyfriend won't!"
Wizard: However, I can say with certainty that fighter is a chaotic stupid oaf. Cleric? You are a litigious bore. And Thief, my dear? You are shockingly incompetent. Thank the gods you got a great ass.
Vashiel of Misfile is actually incapable of lying, so gets some moments like this:
Dr. Upton: Vashiel, tell me, how incompetent is your brother? Vashiel: Oh, very incompetent sir, most of the time!
Elan lampshades this trope (while playing it straight) in "The War Council", where he tells Haley about Therkla.
Redcloak's honesty is brutal in the most literal sense possible near the end of "Loose Ends".
Outsider: The Loroi cannot lie in their telepathy, which means they get used to never lying in any shape or form, whether in telepathy or spoken word. It's implied that their rich warrior history is caused primarily by absolutely none of them bothering with tact. They seem to have gotten better since meeting other races, and their Mizol caste functions in part as diplomats who at least understand and apply tact, but they still tend to be pretty blunt.
Done in The Pain — When Will It End in a (NSFW) comic about the reinventing of the Democrats as "The Sex Party". Confronted with charges of sexual impropriety, the Sex Party candidate responds:
Candidate: Yes. I fucked that woman eight ways to Sunday. I fucked her like I was Paul Bunyan and she was a flapjack the size of Lake Tahoe. I intend to fuck her again immediately after this press conference. Next question?
Pixie and Brutus: In their first meeting, Brutus very quickly points out that Pixie is small, weak, and unable to protect herself. She doesn't get offended.
Marten is offended when Steve tells Dora and him to pick up the other end of a couch. "What, you think I'm too wimpy?" Steve simply says, "Yes." Marten opens his mouth to object, but shuts up when he realises it's true.
Captain Tagon: Sergeant, what are you doing in the ventilation system? Schlock: Listening to you guys. Tagon: You can't just... Tagon: I mean... Kevyn: It's hard to find fault with someone so blunt.
Lalli from Stand Still, Stay Silent has No Social Skills, which means that asking for his input in a conversation will result in this. For instance, if about to go on a dangerous exploration mission and asked what the overprotective older cousin he left back home must be doing, he'll answer "crying" without a second thought. This also means that when he does say something nice, he means it.
Sweet Home (2017): One of the main reasons why Hyuk is disliked is that he doesn’t sugarcoat anything. He tells Hyun right off the bat that he is going to go on dangerous missions or be kicked out, doesn’t hesitate to refer to the kids as dead weight, and tells Hyun that he is going to be bait in their next mission. It almost serves as a deconstruction, since while honesty is usually a good thing in a leader, Hyuk is too honest and makes everyone hate him in the process. Later on, as a result of this honesty, the other flat survivors are more willing to believe the lies of the criminals who arrived on the bus.
Hoh: This is the limit of my talent. I don't really get why I was placed in the Wave Controller position. Don't you agree, Mr. Laure? Laure: That's right. Bam: Oh no, I don't think so. You must be talented in— Laure: Nope.
While Tina of Wapsi Square is usually extremely positive and has been known to, in the words of the other characters, "Blow sunshine up your ass," she considers it her duty to be brutally honest with those she considers friends.
In Weak Hero, the reason that Donald trusts Chungil enough to enter into a business partnership is because Chungil's completely transparent about their relationship being strictly for-profit, and doesn't pretend that there's any actual friendship or goodwill between them.