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The Binding of Isaac has a extremely dark and haunting — and beautiful — soundtrack.
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Original game + Wrath of the Lamb
The Binding of Isaac soundtrack was done by Danny Baranowsky, already well-known for his awesome video-game music, which includes such titles as Canabalt and Super Meat Boy. Original game
- The main theme (and arguably, Isaac's theme) of the game, "The Binding of Isaac". Completely captures the sinister, yet bright tone of the game.
- "Sacrificial", the Basement's theme, sets up the haunting atmosphere of the game quite nicely. It helps that it's the Background Music for the first level, so it's going to worm its way into your ears at one point or another.
- The normal boss theme, Divine Combat and the alternate theme, "Crusade", both set a hectic feel for the first few boss battles.
- The theme for fighting Mom, "Thine Wrath...", especially the parts where the chorus joins in showing that Isaac has a little hope.
- The theme of Mom's Heart and It Lives, "...Be Done". Especially the Ominous Pipe Organ parts.
- Sheol's boss, on the other hand, has "Enmity of the Dark Lord", which also does a fantastic job getting the player pumped up for the fight. Rock Me, Asmodeus!, indeed.
- The music that plays in Sheol, "A Mourner Unto Sheol", is incredibly eerie and foreboding, to the point where it's arguably creepier than Rebirth's version... yet some parts are oddly soothing, to a point. It certainly shows that Sheol is cold, bleak, and empty.
- The tune that plays on the credits after defeating It Lives! for the first time. It comes as a great surprise because it replaces the BGM that usually plays on that sequence... And it's creepy as hell! Made worse by the fact that it's called "Jesus Loves Me".
Wrath Of The Lamb
- Lament of the Angel, a holy rearrangement of "A Mourner Unto Sheol", counterbalancing the hellish Sheol itself with the Cathedral.
- The theme for the boss of The Cathedral (and by extension, The Chest), the absolutely majestic Boss Remix of the main theme, "My Innermost Apocalypse". It made #1 on Klagmar's "Top 50 Final Boss Themes"; it's that good.
Rebirth
While many fans were sad that Danny B. did not return for Rebirth, Ridiculon (Matthias Bossi and Jon Evans) performed excellently in his stead. Rebirth
- "Crusade" is a rocking boss theme that prepares you for the various fights of this game.
- While The Cellar has always been That One Level, "Periculum", the driving rock theme that plays as you battle through it, more than makes up for it.
- Mom gets the fast-paced and frantic "Matricide" as her new battle theme, adding a strong sense of panic and urgency to the fight.
- The theme of Mom's Heart/It Lives, "Ventricide", which periodically switches between intense and creepy in a heartbeat.
- Satan (and Mega Satan) gets one of the most amazingly epic vocal tracks for his new battle theme: "Hericide". The in-game version of "Hericide" is a bit different with a heavier emphasis on the drums, which makes it even more awesome.
- There's an equally epic vocal track for Isaac's own boss fight: "Infanticide".
- The Cathedral itself gets a nice, calming theme in the form of "Everlasting Hymn".
- While Sheol gets the disturbingly demonic "Duress".
- The Chest receives a theme worthy of The Very Definitely Final Dungeon: "Sketches of Pain".
- The Chest's Final Boss receives "Ascension". "Pueris... diabolum..."
- The Dark Room's Final Boss gets the incredibly creepy "The Fallen Angel". Like "Hericide", the in-game version of "Fallen Angel" is a bit different, with heavier emphasis on the vocals, making it even creepier.
- Hush (Jesus Loves Uke), the creepy song that is supposed to replace "Jesus Loves Me" but was cut due to ESRB rating concerns. Thankfully Repentance added it back and added a new version once you achieve Dead God.
- The Forgotten, the Secret Room theme, is a calm theme compared to the rest of the game.
Bonus Tracks
- There's a bonus song on the soundtrack called "He's the Number One." And it's so bizarre it's hilarious.He's the number one. God's favorite son. His flowing robes reach down from heaven. His hands will touch you! Build a world around you! The light within his heart is enough to heal us all! He will fill your soul when life takes its toll. Your only goal is to find his kingdom. His love is real! The golden seal! Trust in the book and the bread you took!
- Descensum sounds like Sheol's alternate theme.
- "Satan 666", a bonus track that costs $6.66, sounds like an alternate unused theme for Satan. Too bad we can't give you the links due to legal issues.
Afterbirth
The expansion came with a new selection of everything, including music, once more by Ridiculon. Afterbirth
- A variation/Boss Remix on the title theme, "Chorus Mortus". Definitely gets the player pumped throughout the chaotic battle that is ULTRA GREED, Greed Mode's Final Boss.
- A new alt boss theme, "Cerebrum Dispersio", which apparently randomly replaces the standard boss music.
- "Nativitate", which is sadly wasted on what amounts to a single room before the Superboss.
- When "Morituros" starts playing, you know you're in for the fight of your life against the resident Superboss. Laden with heavy guitars and punctuated with unsettling, ethereal notes, this theme is perfect for fighting the Bullet Hell happy Eldritch Abomination Marathon Boss that is Hush. As an added bonus, at the beginning of the track, it sounds like they’re chanting the name Hush in the background, assumedly displaying it as a supernatural demon.
- "Fundamentum", the awesomely eerie but hard-rocking theme for the Burning Basement.
- Kave Diluvii, the Flooded Caves theme, almost relaxing while still keeping a measure of tension.
- "Pulso Profundum", a new theme for the Dank Depths. Like the rest of Chapter 3's music, it's very creepy.
- "Cicatrix", the Scarred Womb theme. An utterly unsettling and foreboding theme fit for the equally unsettling level that it plays during. In medical terminology, a cicatrix is the scar of a healed wound.
Bonus Tracks
- Dear Diary is even better, which has Isaac rapping about his plight in the most twistedly funny way imaginable."Once I though I had it good, probably Mom misunderstood, when God came down from heaven, and turned the shit up to eleven."
Afterbirth†
The music for the new Very Definitely Final Dungeon draws many successful runs to an end with some epic tunes. Afterbirth†
- "Terminus", the track for the honest-to-God-we-mean-it-this-time final floor, the Void, incorporates elements of the title theme in combination with some good-old-fashioned hard rock for a tune that will get you pumped up to overcome the game's final challenge.
- "Delirium", the track for the absolute True Final Boss of Afterbirth+ (whose name is the same as the track). The heavy metal and overall chaos really does a good job of illustrating just how insane the battle is (in more ways than one).
Bonus Tracks
- "Locus" feels like an unused boss theme that could play during Delirium.
- "Ante Lucum" sounds like an unused Antibirth stage.
Repentance
With lots of alternate floors and new content, there is bound to be a good number of bangers. Repentance
- The new title theme, "Genesis Retake Light", is another remix of Rebirth's title theme, but with most of the heavy percussion removed, which gives it a sombre tone reminiscent of the original Flash game. Genesis Retake Dark, used for the alternate characters, has Matthias's great singing voice.
- "Juggernaut" is a frantic boss theme that prepares you for the harder bosses. Speaking of bosses, the Boss Rush gets a new theme, "Armageddon".
- The new song for the Downpour, "River of Despair", is a slow, depressing theremin track mixed with ambient noises of water, perfectly tying in all of the Downpour's themes. If one even listens closely, it even sounds very similar to the Dungeon theme for the game that inspired this very game, The Legend of Zelda.
- The Dross' theme, "Night Soil", captures the grimy feel of an Absurdly Spacious Sewer level.
- "Fissure", the new music for the Mines. Gone is the atmospheric and subtle theme from Antibirth. Instead, we get a blaring, aggressive, and intense piece fitting one of the biggest Difficulty Spikes in the game. Meanwhile, the Ashpit's "Absentia" is an epic piece full of wailing guitars that call back to the Burning Basement's song.
- "Walls of Denial", the new theme for the Mausoleum, blends dark atmosphere (thanks to its use of Ominous Latin Chanting) with crushing heaviness, especially in its combat sections, making for a very oppressive (and also strangely heroic) track that fits perfectly with the Nintendo Hard nature of the Mausoleum. "Morning Star" , Gehenna's theme has Legend of Bumbo vibes.
- Remember "Spinning Intensifies" and the Corpse theme from Antibirth? "Dread" and "Carrion" both match up to the creepiness of the original two songs.
- Caesarian, Utero's theme, feels like the perfect mix of the old Rebirth style music with the new added style Ridiculon is going for with the Repentance soundtrack.
- Morticide remixes the Corpse theme and turns it into an intense boss theme for Mother.
- Travelling Back (After Getting Dad's Note) is the song that plays during the Ascent. It's an awesome remix of Genesis, played backwards with additional instrumentation added in the further you go, plays throughout. It really helps sell the idea of Isaac going all the way back to the beginning, all in a heartrendingly beautiful version of the title theme that doesn't lose the tearjerking potential despite sounding warped and strange.
- Home, a beautiful piano theme prepares you for the intensity of Dogma and The Beast. The calm before the storm, indeed.
- "Living in the Light", the chaotic theme for Dogma, symbolizes the fundamentalist propaganda that turned Isaac's mother insane, and has voice lines imitating various televangelists in the background that are screaming Bible verses at the top of their lungs. It quickly became one of, if not the most popular tracks in the game. As a bonus, it's also a Boss Remix of the first boss theme, Crusade, further highlighting the Where It All Began nature of Home and Dogma.PRIDE! GREEEED! WRRRATH! EN-VY! LUST! GLUTTONY, AND SLOTH! So put to death the sinful earthly things lurking within you; have nothing to do with sexual immo-rality! BLASPHEMY AGAINST THE HOOO-LYYY SPIRIIIIIIIT!!
- And for the True Final Boss after 10 years of new content, Revelations 13:1, theme of the Ultra Harbingers and THE BEAST, is a hard rock song that change based on phase (Especially the epic One-Woman Wail that kicks in during Death's phase), similar to Final Fantasy VI's "Dancing Mad".
- The End is an epic conclusion to 10 years of Isaac's torment, finally giving Isaac the final ending he deserves.
Antibirth and Mudeth's music for Repentance
Mudeth's music of Antibirth is comparable to both Danny B. and Ridiculon's. Since he made a whole new soundtrack for the new floors of Repentance and released the soundtrack as a mod for the extension, we'll put it here for the sake of convenience. The mod has all original music, even for the vanilla floors, and they are all of professional quality. Main game
- Innocence Glitched, the new theme for the Basement, is incredibly catchy, especially the middle parts of the song.
- Edmund You Little, a snippet of Innocence Glitched that has some...special vocals.
- Forgotten Lullaby, the music that plays in Secret Rooms (as well as the trailer for the mod itself), is a mellow piece, befitting a room that has been lost to time... before transitioning into an absolutely beautiful piano rendition of Sacrifical at the 45 second mark, marking it as a love letter to the original Flash soundtrack.
- Shadowdance, Sheol's theme, is a spooky and upbeat tune makes you feel like demons and Satan are having a party in Sheol. Shaka shaka ding ding...
- Morphine, The Dark Room theme, is one of the most depressing tracks in the entire game. It perfectly matches a purgatory, eerie, and creepy, every sound seems like someone sorrowing while withering away into nothing while inside this fate worse than hell.
- The Thief makes it feel like you're not supposed to be in the Cathedral but you have to.
- Gloria Filio, the theme of Mom's Heart, a slower but no less triumphant and dramatic rock theme with an audible heartbeat keeping time.note
- Spinning Intensifies. It sounds like Lavender Town, HILL Act 1, and the Reverse Song of Healing all rolled into one. It's almost as if the game is telling you "you've made a horrible, horrible mistake" — not completely unfounded since you just killed your mother, and this is a grave reminder that she's dead.
- Drowning, the Corpse theme, fits the rotting, melting visuals of the insides of a dead body (not to mention those grotesque shadows over the rooms).
- Memento Mori, the epic finale with the Witness/Mother. Remember: You will die!
Antibirth Vol. 3
Published on June 1st, 2021, Antibirth Vol. 3 contains tracks for the rest of the missing content up to Afterbirth+. None of them disappoint, and indicate that the next volume for the Repentance content will be just as epic!
- Foreigner in Zeal, theme for the Flooded Caves and one of the first tracks revealed. A wonderful, mysterious, and somewhat peaceful theme that makes you want to explore the wet depths of the caves.
- Allnoise, The Void theme, makes every single floor motif come together, every single different location Isaac's visited so far falling apart and coming back together in Isaac's mind while it collapses.
- Spectrum of Sin, the Satan theme, just sounds intense, giving a feeling like when Danny did the music for Isaac. It even comes with some dark chanting (which sounds like an even darker version of "The Thief" and "Misericorde", the themes for Cathedral and Isaac, respectively) which seems to give a feeling something even worse is coming if you do kill Satan.
- Fitnah, the theme of The Lamb, feels like a normal Castlevania game suddenly derailed into DOOM-like gorey hell.
- A Baleful Circus is what it says. A circus of bosses all coming together to put on a show to end you. The main attraction? You, of course!note
- Speaking of circuses, Non-Funkible Token sounds like a circus, where you are just a pawn at Ultra Greed's game.
- The Turn, where Isaac finally decides to fight his mother after all of the abuse she put on him. With a little bit of a title remix thrown in and a feeling that doing this will have some consequences.
- Howl is both energizing and... weirdly methodical, playing right into the war of attrition that is this fight against Hush.
- Terminal Lucidity for Delirium is a chaotic and tragic theme showing the losing battle that Isaac is having with himself as he slowly dies with all of his dreams.
- Lethe: how perfect that The Scarred Womb, giver of life, has music that sounds like a distorted and maniacal lullaby.
- Invictus slaps harder than a normal boss fight should, almost with the epicness of a Final Boss fight.
- Rapturepunk gives off a powerful weight when fighting against the Blue Baby, the heavy instruments foreboding something that is about to beat you to the ground.