- Winning any struggle against the big, muscular convict mutants first encountered in Carny. G and Det. Washington will put aside their guns and take it on hand-to-hand, gorily dispatching it with whatever's conveniently nearby. Special mention with the one-liners, such as G's "Hammer Time!"
- During the final chapter, Isaac proudly proclaims that "the 'G' stands for 'genocide', motherfucker!", showing how far he and G have come since Isaac's "Wassup, motherfucker?!" sucker-punch greeting.
- At the end of the game, while G and Isaac are on their way out via helicopter, they find out that their pilot is a mutant. Without flinching, the two heroes draw their guns and the screen cuts to black. You can most likely guess what happened next.
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