Especially when you remember that one of George and Harold's pranks in the books was to rig the school intercom to play Weird Al music all day.
In the beginning, George and Harold finally give us an origin issue of Captain Underpants!
The scene where Mr. Krupp becomes Captain Underpants for the first time, especially to long-time fans that grew up reading the books. Because it's not just George and Harold witnessing their creation come to life, it's the fans witnessing their childhood come to life!
The scene where Captain Underpants gets his superpowers. And unlike when it happened in Book 3, George and Harold think it's the coolest thing ever.
Harold: No way! George: He has real superpowers! Harold: Aw, that is an obvious twist I did not see coming despite my many years of comic book studies! (The two high-five one another.)
Special mention needs to go to the beginning of the fight between Captain Underpants and Professor Poopypants. Captain Underpants doesn't hesitate for a second before jumping into battle against the villain, and despite being thoroughly disadvantaged not possessing superpowers at the time, he fights on anyway.
Another small example, but Captain Underpants landing on a robber duo, thwarting their getaway with several bags of stolen bank money right in time for the police to show up and arrest them. This is his first success as a crime fighter as well as a shout out to a similar scene from the first book.
Several of the pranks themselves are rather impressive, as George and Harold Lampshade:
George: Some of those must have been really hard to pull off.
Harold: And dangerous! Like that tiger!
George: Oh, that tiger was crazy!
George's rousing speech to convince Harold to help him hijack Melvin's Turbo Toilet 2000 and liberate their peers from enduring another minute of boredom at the school's Invention Convention:
George: Look at our fellow children! Look upon their sad, miserable, pathetic faces! Come on, Harold! If you won't do it for me and you won't do it for you, do it for future generations! Save the first graders, the kindergartners, the unborn, from a life of eternal boredom!
Melvin and Krupp's Batman Gambit to acquire proof of George and Harold pulling a prank with a disguised nanny cam in a stuffed turtle toy deserves due credit.
George: Forged from the molten plastic of Shandong, China... In the lowest floor of the darkest basement where only toy prizes dare be made... exists the most powerful item ever found in a box of Frosted Sugar Doodles! The Hypno Ring!
Unlike in the books, there are no directions as to how to use the Hypno-Ring. George just guessed and improvised his way through figuring it out.
George: (to a hypnotized Mr. Krupp) When I snap my fingers, you will obey our every command!
Harold: Wait, how do you know all this? George: I dunno. I just say the first thing that comes to my mind with great authority!
The boys steal a crane to chase after Captain Underpants though town. After initial trial and error, Harold manages to operate it with stellar ease, even managing to perfectly parallel park the thing! Keep in mind, hes only ten!
Harold's marksmanship skills. In the scene where they first enter the treehouse, he slingshots a pebble at the pinwheel from a decent distance with exceptional accuracy, then far more impressively later in the climax, is able to restore the shrunken Captain Underpants and the school back to normal with one shot from a far greater distance.
The scene where George and Harold enter the school dancing to Yellos Oh Yeah is both this and a Funny Moment. Ferris Bueller would be proud.
All the creativity George and Harold incorporate into their pranks and inspire in others. When they hack Melvin's Turbo Toilet 2000 to fire rolls of toilet paper and play music a la dance party, watch what the other students do. One uses a toilet paper roll to perform a makeshift ribbon dance, another wraps himself up and pretends to be a mummy, several others craft a trampoline, use it as jump ropes, and even circus ribbon trapeze acts to name a few. When it happens again during the climatic battle, they use the super sized TP in a similar vein, such as for making an improvised slide among other activities. George and Harold may have kickstarted the impromptu dance parties, but it was the other students themselves who took what was provided at their disposal and utilized it various in unique ways to have fun to their choosing with their own ideas/ingenuity, building off of what the boys started. It really shows how much of an impact they have doing what they do for their school peers.
And this is just what they came up with using only rolls of toilet paper!! Imagine the possibilities of what they can accomplish applying that same creative ingenuity into other things!
The boys launch themselves to the top of the Turbo Toilet 2000, but only narrowly so. Harold uses one hand to support both his and George's weight hanging onto the edge, and the other to swing George up the rest of the way.
Harold using his enlarged hand to physically fight back against the giant Professor Poopypants, as well as to save Georgefrom a shrink blast, which simultaneously restores his hand to normal.
Captain Underpants saving George and Harold from Professor Poopypants after receiving his newly acquired superpowers, then later from the Talking Toilets at the end.
George and Harold resisting the effects of Professor Poopypants' Anti-Humor Ray. It takes Poopypants cranking it up two more notches in order for Harold to lose his sense of humor and then the ray has to be on full force for George to lose his.
And it doesn't even last for long. They inevitably overpower and destroy it when they recall a memory of how they connected as friends through their shared sense of humor.
George: Never underestimate the power of laughter, Poopypants!
Meta and Non-Canon
The movie being created in the first place is one gigantic Moment of Awesome in itself. When Dav Pilkey was writing comic books in grade school, his teachers and principal told him he would never amount to anything and he couldn't spend the rest of his life making silly books. He grew up, got Captain Underpants published, and it sold like hotcakes. 20 years and 11 books after the publication of the first Captain Underpants book, it became a full-fledged 3D animated movie produced by DreamWorks Animation, to the delight of fans everywhere. Can anyone say "Who's Laughing Now?"
Speaking of which, a fan asked Dav on Instagram if he ever saw said teachers and principal again after the success of the Captain Underpants series, and this was his response. Way to be the bigger man, Dav.
No, I never saw any of them after my books started coming out. I had a few opportunities to, but I declined. Sometimes its best to put the past behind you. #nohardfeelings #noregrets