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S
- Daryl Sabara
- Evan Sabara
- Dan Sachoff
- Katee Sackhoff
- William Sadler
- Thomas Sadoski
- Bryan Safi
- Salli Saffioti
- Katey Sagal
- Ernie Sabella
- Halston Sage
- Melissa Sagemiller
- Bob Saget
- Eva Marie Saint
- Susan Saint James
- James Saito
- Nichole Sakura
- George Salazar
- Rosa Salazar
- Zoe Saldaña
- Meredith Salenger
- Diane Salinger
- Matt Salinger
- Benjamin Salisbury
- Mark Salling
- Albert Salmi
- Frank Salsedo
- William Salyers
- Andy Samberg
- Kendrick Sampson
- Will Sampson
- Jeffrey D. Sams
- Russell Sams
- Skyler Samuels
- Kiele Sanchez
- Marco Sanchez
- Otto Sanchez
- Rigo Sanchez
- Roselyn Sánchez
- Cole Sand
- Paul Sand
- Casey Sander
- Aaron Sanders
- Erin Sanders
- Christoph Sanders
- Henry G. Sanders
- Jay O. Sanders
- Tyler Sanders
- Adam Sandler
- Miguel Sandoval
- Olivia Sandoval
- Diana Sands
- Ryan Sands
- Stark Sands
- Ellen Sandweiss
- Lily Sanfelippo
- Isabel Sanford
- Merlin Santana
- Ray Santiago
- Ruben Santiago-Hudson
- Saundra Santiago
- Reni Santoni
- Joe Santos
- Nico Santos
- Carlos Sanz
- Horatio Sanz
- Mia Sara
- Chris Sarandon
- Susan Sarandon
- Dick Sargent
- Peter Sarsgaard
- Elena Satine (Georgian expatriate)
- Sherri Saum
- Andrea Savage
- Ben Savage
- Fred Savage
- John Savage
- George Savalas
- Telly Savalas
- Doug Savant
- Danielle Savre
- Devon Sawa (Canadian expatriate)
- Connie Sawyer
- Alex Saxon
- John Saxon
- Raphael Sbarge
- Peter Scanavino
- Jeffrey Scaperrotta
- Sam Scarber
- Cassie Scerbo
- Diana Scarwid
- Kristen Schaal
- Wendy Schaal
- Johnathon Schaech
- Rebecca Schaeffer
- Hunter Schafer
- William Schallert
- Mary Scheer
- Lou Scheimer
- Ronnie Schell
- Vincent Schiavelli
- Mark Schiff
- Richard Schiff
- Taylor Schilling
- Steve Schirripa
- Lavel Schley
- Inga Schlingmann
- Kendall Schmidt
- Kevin G. Schmidt
- Wrenn Schmidt
- Noah Schnapp
- John Schneider
- Paul Schneider
- Jill Schoelen
- Dylan Schombing
- Jason Schombing
- Bitty Schram
- Jessy Schram
- David Schramm
- Avery Schreiber
- Liev Schreiber
- John Schuck
- Amanda Schull
- Dwight Schultz
- Matt Schulze
- Paul Schulze
- Amy Schumer
- Aaron Schwartz
- Ben Schwartz
- Arnold Schwarzenegger (Austrian-American dual citizen)
- Patrick Schwarzenegger
- David Schwimmer
- Rusty Schwimmer
- Annabella Sciorra
- Walker Scobell
- Tracy Scoggins
- Peter Scolari
- Adam Scott
- Ashley Scott
- Campbell Scott
- Esther Scott
- George C. Scott
- Jill Scott
- Judith Scott
- Judson Scott
- Kathryn Leigh Scott
- Kimberly Scott
- Lizabeth Scott
- Marielle Scott
- Randolph Scott
- Reid Scott
- Seann William Scott
- Stefanie Scott
- Tom Everett Scott
- Vito Scotti
- Marcus Scribner
- James Scully
- John Scurti
- Ryan Seacrest
- Steven Seagal
- Amanda Seales
- Christopher Sean
- Teddy Sears
- Nick Searcy
- Jean Seberg
- Kyle Secor
- Jon Seda
- Amy Sedaris
- Kyra Sedgwick
- Rhea Seehorn
- George Segal
- Noah Segan
- Josh Segarra
- Jason Segel
- Geno Segers
- Ainsley Seiger
- Jerry Seinfeld
- Marian Seldes
- Keidrich Sellati
- Tom Selleck
- Andrew Sellon
- Charlie Semine
- Martin Sensmeier
- Greg Serano
- Ivan Sergei
- Pepe Serna
- Terry Serpico
- Raymond Serra
- Christian Serratos
- Matt Servitto
- Greg Sestero
- Matthew Settle
- Amanda Setton
- Joan Severance
- Chloë Sevigny
- Amanda Seyfried
- Jane Seymour (Actress) (British-American)
- Glenn Shadix
- Robert R. Shafer
- Sarah Shahi
- Yara Shahidi
- Matt Shakman
- Tupac Shakur
- Tony Shalhoub
- Jeremy Shamos
- Aleyse Shannon
- Michael Shannon
- Michael J. Shannon
- Vicellous Shannon
- Adam Shapiro
- Brighton Sharbino
- John Sharian
- William Shatner (Canadian expatriate)
- David Shatraw
- Shari Shattuck
- Grant Shaud
- Doc Shaw
- Vinessa Shaw
- Wallace Shawn
- Lin Shaye
- John Shea
- Harry Shearer
- Ally Sheedy
- Charlie Sheen
- Martin Sheen
- Craig Sheffer
- Adrienne Shelly
- Paul Shenar
- Justin Shenkarow
- Ben Shenkman
- Shelly Shenoy
- Dax Shepard
- Hilary Shepard
- Quinn Shephard
- Cybill Shepherd
- Sherri Shepherd
- Suzanne Shepherd
- Eden Sher
- Tasia Sherel
- Ann Sheridan
- Jamey Sheridan
- Kevin Sheridan
- Liz Sheridan
- Nicollette Sheridan
- Taylor Sheridan
- Tye Sheridan
- Sarah Sherman
- Robin Sherwood
- Reshma Shetty (dual British-American citizenship)
- Blake Shields
- Brooke Shields
- Sab Shimono
- Eddie Shin
- Kiernan Shipka
- Madisyn Shipman
- Alexandra Shipp
- John Wesley Shipp
- Talia Shire
- Matt Shively
- Richard Shoberg
- William Shockley
- Dinah Shore
- Pauly Shore
- Grant Show
- Andrew Shue
- Elisabeth Shue
- Maz Siam
- Jane Sibbett
- Graham Sibley
- Gabourey Sidibe
- Sylvia Sidney
- James Sie
- Kate Siegel
- Nina Siemaszko
- Maggie Siff
- Jamie-Lynn Sigler
- Stephanie Sigman
- James B. Sikking
- Allison Siko
- Joseph Sikora
- Henry Silva
- Leslie Silva
- Michael B. Silver
- Ron Silver
- Jonathan Silverman
- Laura Silverman
- Sarah Silverman
- Phil Silvers
- Alicia Silverstone
- Keong Sim (born in Vietnam to Korean parents and was raised in the US)
- Justin Simien
- Diggy Simmons
- Henry Simmons
- Jean Simmons (British-American actress)
- J. K. Simmons
- Johnny Simmons
- Lili Simmons
- Richard Simmons
- Millicent Simmonds
- Ty Simpkins
- Ashlee Simpson
- Jessica Simpson
- O. J. Simpson
- Jocko Sims
- Frank Sinatra
- Nancy Sinatra
- Sinbad
- Jaz Sinclair
- Guy Siner (born in America but moved to England in his youth. Briefly moved back to America from the late '90s to early 2000s)
- Isaac C. Singleton Jr.
- Gary Sinise
- Sadie Sink
- Tiya Sircar
- Kofi Siriboe
- Tony Sirico
- Marina Sirtis (British-American dual citizen)
- Jeremy Sisto
- Meadow Sisto
- Rocco Sisto (Italian-American)
- Alicia Sixtos
- Kevin Sizemore
- Tom Sizemore
- Red Skelton
- Tom Skerritt
- Alex Skuby
- Jennifer Sky
- Azura Skye
- Ione Skye
- Jenny Slate
- Christian Slater
- Helen Slater
- Brittany Slattery
- John Slattery
- Jonathan Slavin
- Amy Sloan (Canadian-American)
- Matt Sloan
- Lindsay Sloane
- Ptolemy Slocum
- Joey Slotnick
- Samantha Sloyan
- Tucker Smallwood
- Amy Smart
- Jean Smart
- Robert Smigel
- Allison Smith
- Anna Deavere Smith
- Arjay Smith
- Art Smith
- Brady Smith
- Brian J. Smith
- Brian Michael Smith
- Brooke Smith
- Bubba Smith
- Charles Martin Smith
- Cory Michael Smith
- Cotter Smith
- Courtney Thorne-Smith
- David Lee Smith
- Hal Smith
- J. Smith-Cameron
- Jaclyn Smith
- Jacob Smith
- Jaden Smith
- Justice Smith
- Kerr Smith
- Kevin Smith
- Kurtwood Smith
- Lane Smith
- Lois Smith
- Michael Bailey Smith
- Patricia Smith
- Paul L. Smith
- Peyton Alex Smith
- Phyllis Smith
- Renee Felice Smith
- Riley Smith
- Roger Craig Smith
- Samantha Smith
- Sandra Smith
- Shawnee Smith
- Taran Noah Smith
- Will Smith
- William Smith
- Willow Smith
- Yeardley Smith
- Jimmy Smits
- Jurnee Smollett
- Jussie Smollett
- J.B. Smoove
- Johnny Sneed
- Wesley Snipes
- Brittany Snow
- Drew Snyder
- Liza Snyder
- Shayan Sobhian
- Leelee Sobieski
- Rena Sofer
- Jesse Lee Soffer
- Sonja Sohn
- Marilyn Sokol
- Marla Sokoloff
- Sky Soleil
- P. J. Soles (born in West Germany)
- Felix Solis
- Kyle Soller
- Suzanne Somers
- Bonnie Somerville
- Julie Sommers
- Josef Sommer (German-American actor)
- Rich Sommer
- Brenda Song
- Trey Songz
- Karan Soni (Indian-American)
- Pepi Sonuga (Nigerian-American)
- Phillipa Soo
- Bahar Soomekh
- Alisha Soper
- Kevin Sorbo
- Corey Sorenson
- Michael Sorvino
- Mira Sorvino
- Paul Sorvino
- Shannyn Sossamon
- Talisa Soto
- Kath Soucie
- David Soul
- Dan Southworth
- Sissy Spacek
- Kevin Spacey
- David Spade
- James Spader
- Cailee Spaeny
- Douglas Spain
- Joe Spano
- Vincent Spano
- Aries Spears
- Eddie Spears
- Michael Spears
- Richard Speight Jr.
- Tori Spelling
- Abigail Spencer
- Chaske Spencer
- John Spencer
- J Robert Spencer
- Octavia Spencer
- Wendie Jo Sperber
- David Spielberg
- Sasha Spielberg
- Joe Spinell
- Stephen Spinella
- Brent Spiner
- Caroll Spinney
- Doug Spinuzza
- Emily Spivey
- Suanne Spoke
- Gregory Sporleder
- Taylor Spreitler
- Cole Sprouse
- Dylan Sprouse
- Marina Squerciati
- Mark St. Cyr
- David St. James
- Austin St. John
- Jill St. John
- Kelly Stables
- Ari'el Stachel
- Robert Stack
- Timothy Stack
- Nick Stahl
- Richard Stahl
- Frank Stallone
- Sylvester Stallone
- Josh Stamberg
- Lauren Stamile
- John Stamos
- Sebastian Stan
- Darby Stanchfield
- Aaron Stanford
- Arnold Stang
- Christopher Stanley
- Florence Stanley
- Ian Stanley
- Sadie Stanley
- Taylor Stanley
- Harry Dean Stanton
- Jack Stanton
- Matthew Stanton
- Barbara Stanwyck
- Jean Stapleton
- Maureen Stapleton
- Don Stark
- Anthony Starke
- Anton Starkman
- Martin Starr
- Mike Starr
- David Starzyk
- Aaron Staton
- Amy Steel
- Sarah Steele
- Mary Steenburgen
- Michael Steger
- Jack Stehlin
- Rod Steiger
- Ben Stein
- Hailee Steinfeld
- Nicole Steinwedell
- Amandla Stenberg
- Brian Stepanek
- Heather Stephens
- James Stephens
- Louanne Stephens
- Bob Stephenson
- Maury Sterling
- Mindy Sterling
- Daniel Stern
- Jenna Stern
- Shoshannah Stern
- Frances Sternhagen
- Patrick St. Esprit
- Paul Morgan Stetler
- Brody Stevens
- Fisher Stevens
- Katie Stevens
- Kia Stevens
- Cynthia Stevenson
- McLean Stevenson
- Booboo Stewart
- Coy Stewart
- French Stewart
- Jimmy Stewart
- Jon Stewart
- Kristen Stewart
- Lynne Marie Stewart
- Peggy Stewart
- Tonea Stewart
- Ari Stidham
- David Ogden Stiers
- Julia Stiles
- Ryan Stiles
- Ben Stiller
- Jerry Stiller
- Galadriel Stineman
- Barbara Stock
- Dean Stockwell
- Guy Stockwell
- Nickolai Stoilov (Bulgarian-American)
- Corey Stoll
- Fred Stoller
- Christian Stolte
- Eric Stoltz
- Christopher Stone
- Emma Stone
- Matt Stone
- Rob Stone
- Sharon Stone
- Roger Stoneburner
- Alyson Stoner
- Larry Storch
- Ptosha Storey
- Madeleine Stowe
- Michael Stoyanov
- Beatrice Straight
- Deborah Strang
- Lee Strasberg (Polish-American)
- Marcia Strassman
- Dorothy Stratten (Canadian expatriate)
- Kim Strauss
- Meryl Streep
- Barbra Streisand
- KaDee Strickland
- Sherry Stringfield
- Elaine Stritch
- Woody Strode
- Brenda Strong
- Cecily Strong
- Danny Strong
- Rider Strong
- Tara Strong (Canadian-American dual citizen)
- Sally Struthers
- Gloria Stuart
- Tara Subkoff
- Olivia Stuck
- Wes Studi
- Geoff Stults
- Brooklyn Sudano
- Skipp Sudduth
- Jason Sudeikis
- Alison Sudol
- Sterling Sulieman
- Barry Sullivan
- Chris Sullivan
- Erik Per Sullivan
- Nancy Sullivan
- Nicole Sullivan
- Susan Sullivan
- Aya Sumika
- Cree Summer (Canadian-American dual citizen)
- Ronan Summers (Irish-American dual citizen)
- Mina Sundwall
- Jeremy Sumpter
- Tika Sumpter
- Elizabeth Sung (Chinese-American)
- Daniel Sunjata
- Ethan Suplee
- Todd Susman
- Steve Susskind
- Josh Sussman
- Kevin Sussman
- Kiefer Sutherland (British-Canadian expatriate)
- Carol Sutton
- Mena Suvari
- Dominique Swain
- Emily Swallow
- Hilary Swank
- Gloria Swanson
- Kristy Swanson
- Don Swayze
- Patrick Swayze
- Heidi Swedberg
- D.B. Sweeney
- Julia Sweeney
- Sydney Sweeney
- Terry Sweeney
- Inga Swenson
- Jodie Sweetin
- Francie Swift
- Taylor Swift
- Quintessa Swindell
- Kitty Swink
- Loretta Swit
- Wanda Sykes
- Robert Symonds
- Keith Szarabajka
- Eric Szmanda
- Jessica Szohr
T
- Kristoffer Tabori
- Babak Tafti
- Cary-Hiroyuki Tagawa
- Rita Taggart
- Saïd Taghmaoui (French-American dual citizen)
- George Takei
- Michael Talbott
- Marilee Talkington
- Jill Talley
- Steve Talley
- Patricia Tallman
- Dijon Talton
- Ellen Tamaki
- Amber Tamblyn
- Russ Tamblyn
- Sara Tanaka
- Joy Tanner (American-Canadian dual citizen)
- Robert Tapert
- Carl Tart
- Renee Taylor
- Russi Taylor
- Jessica Tandy (British-American dual citizen)
- Meagan Tandy
- Bill Tangradi
- Antwon Tanner
- Brian Tarantina
- Quentin Tarantino
- Barbara Tarbuck
- Joe E. Tata
- Fred Tatasciore
- Larenz Tate
- Sharon Tate
- Jimmy Tatro
- Channing Tatum
- Chelsea Tavares
- Anya Taylor-Joy (American-Argentine-British)
- Bex Taylor-Klaus
- Buck Taylor
- Christine Taylor
- Elizabeth Taylor (British-American dual citizen)
- Frank Hoyt Taylor
- Holland Taylor
- Holly Taylor (Canadian-American)
- James Arnold Taylor
- Jennifer Taylor
- Leigh Taylor-Young
- Meshach Taylor
- Regina Taylor
- Rip Taylor
- Robert Taylor
- Robin Lord Taylor
- Ron Taylor
- Erica Tazel
- Aimee Teegarden
- Miles Teller
- Lew Temple
- Shirley Temple
- Lisandra Tena
- Jon Tenney
- Amanda Tepe
- Lee Tergesen
- Scott Terra
- Taryn Terrell
- Michael Grant Terry
- Gloria Tesch
- Lauren Tewes
- Joan Tewkesbury
- Cheryl Texiera
- Kirk Thatcher
- Sophie Thatcher
- Brynn Thayer
- Maria Thayer
- Robin Thede
- Marcello Thedford
- Angel Theory
- Charlize Theron (South African-American dual citizen)
- Justin Theroux
- Clarissa Thibeaux
- Max Thieriot
- Lynne Thigpen
- Tiffani Thiessen
- Roy Thinnes
- Olivia Thirlby
- Betty Thomas
- Bruce Thomas
- Danny Thomas
- Eddie Kaye Thomas
- Harrison Thomas
- Henry Thomas
- Jay Thomas
- Jonathan Taylor Thomas
- Larry Thomas
- Marlo Thomas
- Michelle Thomas
- Philip Michael Thomas
- Richard Thomas
- Robin Thomas
- Sean Patrick Thomas
- Al Thompson
- Brian Thompson
- Caitlin Thompson
- David W. Thompson
- Fred Thompson
- Kenan Thompson
- Lea Thompson
- Scottie Thompson
- Susanna Thompson
- Tessa Thompson
- Tracie Thoms
- Bella Thorne
- Callie Thorne
- Dominique Thorne
- Lisa Thornhill
- Billy Bob Thornton
- Malachi Throne
- Uma Thurman
- TJ Thyne
- Rachel Ticotin
- Gene Tierney
- Lawrence Tierney
- Maura Tierney
- Kenneth Tigar
- Kevin Tighe
- Tramell Tillman
- Jennifer Tilly
- Meg Tilly
- Theresa Tilly
- Tinashe
- Zach Tinker
- Amy Tipton
- Lio Tipton
- Ashley Tisdale
- Paula Tiso
- Tom Titone
- Christopher Titus
- Brianne Tju
- Haley Tju
- Kenneth Tobey
- Becca Tobin
- Stephen Tobolowsky
- Jacqueline Toboni
- Beverly Todd
- Hallie Todd
- Tony Todd
- Jonathan Togo
- James Tolkan
- Allison Tolman
- David Tom
- Heather Tom
- Lauren Tom
- Nicholle Tom
- Concetta Tomei
- Marisa Tomei
- Tamlyn Tomita
- Sara Tomko
- Lily Tomlin
- Paul F. Tompkins
- Tone Lōc
- Denyse Tontz
- Nick Toren
- Rip Torn
- Nate Torrence
- Gina Torres
- Liz Torres
- Alessandra Torresani
- Guy Torry
- Nico Tortorella
- Josie Totah
- Shaun Toub
- Emeraude Toubia
- George Touliatos
- Sheila Tousey
- Lorraine Toussaint
- Mageina Tovah
- Robert Townsend
- Michelle Trachtenberg
- Spencer Tracy
- Jerry Trainor
- Mary Ellen Trainor
- Saxon Trainor
- Karrueche Tran
- Thuy Trang (born in Vietnam, but raised in the US)
- A. J. Trauth
- Daniel J. Travanti
- Nancy Travis
- John Travolta
- Misti Traya
- Alex Trebek
- Danny Trejo
- Michael Trevino
- Ivan Triesbault (Estonian-American)
- Angela Trimbur
- Thea Trinidad
- Connor Trinneer
- Jeanne Tripplehorn
- Alpha Trivette
- Brandon Trost
- Jason Trost
- Sarah Trost
- Verne Troyer
- Michael Trucco
- Toni Trucks
- Jim True-Frost
- Yanic Truesdale (Canadian-American)
- Irene Tsu (Chinese-American)
- Daisuke Tsuji (born in Kuwait, later moved to Japan at age 2, and later moved to the US at 8)
- Marcelo Tubert (Argentine-American)
- Michael Tucci
- Stanley Tucci
- Jessica Tuck
- Alan Tudyk
- Elizabeth Tulloch
- Jen Tullock
- Tamara Tunie
- Robin Tunney
- James Tupper
- Paola Turbay (Colombian-American)
- Paige Turco
- Brian Turk
- Glynn Turman
- Bree Turner
- Frances Turner
- Guinevere Turner
- Janine Turner
- Karri Turner
- Kathleen Turner
- Lana Turner
- Tina Turner
- Jerry Trainor
- Kelly Marie Tran
- Manu Tupou
- Joe Turkel
- Aida Turturro
- John Turturro
- Nicholas Turturro
- Aisha Tyler
- James Michael Tyler
- Liv Tyler
- Mia Tyler
- Mark Tymchyshyn
- Mike Tyson
U
- Alanna Ubach
- Bob Uecker
- Leslie Uggams
- Tracey Ullman (British-American dual citizen)
- Skeet Ulrich
- Andy Umberger
- Blair Underwood
- Billy Unger
- Gabrielle Union
- Kate Upton
- James Urbaniak
- Robert Urich
- Usher
- Jessie T. Usher
- Jenna Ushkowitz (Korean-American)
- William Utay
V
- Brenda Vaccaro
- Dilshad Vadsaria (Pakistani-American dual citizen)
- Mat Vairo
- David Valcin
- Wilmer Valderrama
- Carlos Valdes
- Erik Valdez
- Nancy Valen
- Scott Valentine
- Steve Valentine (Scottish-American dual citizen)
- Tru Valentino
- Mark Valley
- Jessika Van
- Louis Vanaria
- Joan Van Ark
- Lee Van Cleef
- Sheila Vand
- James Van Der Beek
- Casper Van Dien
- Grace Van Dien
- Barry Van Dyke
- Dick Van Dyke
- Jerry Van Dyke
- Jo Van Fleet
- Brian Van Holt
- Joyce Van Patten
- Mario Van Peebles
- Melvin Van Peebles
- Shantel VanSanten
- Deborah Van Valkenburgh
- Travis Van Winkle
- Courtney B. Vance
- Amirah Vann
- Marc Vann
- Jacob Vargas (Mexican-American)
- Mercedes Varnado
- Jim Varney
- Michael Vartan (French expatriate)
- Danny Vasquez
- Liz Vassey
- Sofia Vassilieva
- Greg Vaughan
- Baron Vaughn
- Countess Vaughn
- Ned Vaughn
- Robert Vaughn
- Terri J. Vaughn
- Vince Vaughn
- Yul Vazquez (Cuban-American)
- Alex Veadov (Ukrainian-American)
- Alexa Vega
- Michelle Veintimilla
- Nadine Velazquez
- Eddie Velez
- Lauren Velez
- Reginald VelJohnson
- Chick Vennera
- Diane Venora
- Briana Venskus
- John Ventimiglia
- Milo Ventimiglia
- Vincent Ventresca
- Jesse Ventura
- Ben Vereen
- Sofía Vergara (Colombian-American dual citizen)
- Tom Verica
- Adam Vernier
- Conrad Vernon
- Cec Verrell
- John Vickery
- Paul Ben-Victor
- Christina Vidal
- Lisa Vidal
- Izabela Vidovic
- Gillian Vigman
- Abe Vigoda
- Zach Villa
- David Villar
- Elliot Villar
- Melissa Villaseñor
- Alex Vincent (Actor)
- Frank Vincent
- Jan-Michael Vincent
- Tom Virtue
- Nana Visitor
- Joe Viterelli
- Sam Vlahos
- Riley Voelkel (Canadian-American dual citizen)
- Mike Vogel
- Jon Voight
- Rita Volk
- Daniel von Bargen
- Erik von Detten
- Lenny Von Dohlen
- Jenna von Oÿ
- Danielle Von Zerneck
- Lark Voorhies
- Caris Vujcec
