- In some of The Simpsons: Treehouse of Horror Halloween specials, Kang and Kodos are aliens from the planet Rigel VII who tend to abduct humans (especially the Simpsons of course) for various reasons. (Though obviously none of these events are canon.)
- In "Treehouse of Horror I" ("Hungry Are the Damned"), the whole Simpson family are taken captive by Kang and Kodos. They're actually very nice and hospitable to the Simpsons, and treat them to a grand dinner feast. However Lisa is suspicious, and she finds a cookbook entitled How to Cook Humans (spoofing the famous The Twilight Zone episode "To Serve Man"). However, Kang and Kodos blow off some dust to reveal the book's title as How to Cook for Forty Humans, and then they kick out the Simpsons for their rudeness.
- In "Treehouse of Horror VII" ("Citizen Kang"), Kang and Kodos abduct Homer Simpson while he's out fishing. Though instead of eating Homer or rectally probing him as he initially feared, the two aliens simply ask to know who the leader of Earth is. Homer answers that it's US President Bill Clinton, though he may be replaced by Senator Bob Dole in the then-current 1996 presidential election. So Kang and Kodos abduct Clinton and Dole in order to impersonate both of them, and they run in the election. They successfully take over America (and the Earth).
- In "Treehouse of Horror IX" ("Starship Poopers"), the Simpsons discover that Homer is not the biological father of Maggie, who is really a half-alien hybrid that was conceived when Marge was abducted by Kang; who, after trying and failing to seduce her, blasted her with an energy beam that made her pregnant with his offspring. Kang arrives with Kodos to kidnap Maggie, which leads to them fighting with Homer, which they then try to settle on The Jerry Springer Show.
- In the Futurama episode "Spanish Fry", Fry gets kidnapped and has his nose stolen by alien poachers, who intend to sell it as a black-market aphrodisiac to Lrr, ruler of the planet Omicron Persei 8. Judging by a news report, alien abduction is a fairly common occurrence in 31st century life.Linda: "Alien abductions: Until now, a harmless nuisance. But recently they've taken on a sinister dimension as unsuspecting victims are returned... without noses."
- In the Recess episode "The Experiment", there's an urban legend about a boy named Jimmy Cratner, who was allegedly beamed up by an alien spaceship and never seen again. At the end, they return Jimmy to his school, who thanks them for the ride.
- In Kim Possible, Drakken is abducted by The Greys once, and the Lowardians snatch both him and Kim.
- The Pilot episode of South Park, "Cartman Gets an Anal Probe." Almost a hundred episodes later ("Canceled") the aliens abducted him again, revealing that their secret motive this whole time was to monitor Earth because it's actually a giant intergalactic reality TV show.
- Chuck Jones put out two alien-abduction themed Looney Tunes — "Hasty Hare" has Bugs captured by Marvin the Martian, and "Jumpin' Jupiter" has a mutant-turkey alien abduct a vacationing Porky Pig in a visually awesome scene where the flying saucer burrows beneath his campsite, and carries off a whole section of ground with tent, campfire, car and all.
- The Walt Disney Presents special "Mars and Beyond" featured a frenetic take on a "typical sci-fi story" where a scientist's secretary is nabbed by aliens, done by Ward Kimball in peerless '50s style.
- Played for laughs on Invader Zim, where the title character, an insane alien posing as a human, gets abducted by a pair of even-stupider aliens who think he really is human. We find out that the aliens are so stupid and ineffective at doing anything, all their victims escaped without harm.
- Parodied and shown from the aliens' point of view in the Pixar Shorts film Lifted. A nervous trainee flying saucer pilot struggles to control his vessel, which is controlled by hundreds of unmarked, completely identical switches, and successfully abduct an Earthling.
- Parodied in a special relating to an episode plot-making contest (of which the episode itself was the direct result of such a contest), where Buster's plot idea was having Buster's character trying to get aliens to come down; they do, landing on Buster's character, and take Arthur's character into their ship, doing anal probing (although, as it is a kids show, Arthur's character is just shown in his underpants, although the implications were still on there), then leave Arthur behind. Also, the entire sequence was a direct Shout-Out to South Park (ironic, considering how that show was anything but kid friendly).
- Similarly, in the episode (and book) "Arthur's Slumber Party", a subplot involved a newspaper headline mentioning that someone thought they saw a UFO. DW got obsessed with UFOs as a result, and so during the slumber party, Arthur, Brain, and Buster decided to pull a few pranks on DW by first placing one of their sleeping bags and using a cutout of an alien to cause DW to think its a real alien, and then (episode only) create a UFO contraption for DW to take pictures of until it landed via Brain's remote control.
- Hilariously implied to be what happened to D.W.'s Snowball in the episode "D.W.'s Snowball".
- Happens to Danger Mouse and Penfold in "Close Encounters of the Absurd Kind". But DM thinks the alien captain is Baron Greenback in disguise.
- Steven Universe: Homeworld initially seemed totally disinterested in humans, only invading Earth to take its resources. Later, we see they also abducted numerous humans to create the starting population of a People Zoo, because one of their leaders found humans interesting. More recently, they decide to expand their Zoo. Because of a misunderstanding from when Steven talked to a Homeworld gem, they start with his friends.
- Solar Opposites: According to Yumyulack, the Shlorpians had been examining humans for thousands of years. As evident by the fact that he didn't know what a brain was or how it worked, not much progress had been made.
- Kaeloo: Happens to Stumpy in Episode 98. The aliens abduct him from the couch he's sitting on and examine some acorns he happened to have with him. Turns out it was All Just a Dream ... Or Was It a Dream?
- Played for Laughs in the first episode of Milo Murphy's Law. The show's premise is that Milo lives with Murphy's Law as a Hereditary Curse, so naturally, he and his friend Zack are beamed up by aliens while they're already late for school.
- Milo: (Tied to a table as the aliens clean some weird tool) You know, they are from out of town. Maybe they don't even realize they're inconveniencing us.
- Zack takes this advice, explains to the aliens that they need to be somewhere, and they teleport the boys into their classroom seconds before the bell rings.
- In Season 2, Milo meets the squid-like Octalians when they abduct him for unknown purposes. Unfortunately for the aliens, Milo's curse causes disaster after disaster on their ship until they are forced to drop him back on Earth and flee by escape pod. They return and abduct him again at the end of season, where its revealed they actually want him to come solve a crisis on their homeworld. Milo points out that they could have just requested his assistance up front instead of kidnapping him.
- American Dad!: Happens at the end of the episode "Naked to the Limit, One More Time", where Roger shoves Jeff into the tractor beam of the ship sent to rescue him. His fate was shown in the episode "Lost in Space".
Alien Abduction / Western Animation