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1->''"Think about what Darwin wrote, and think about me. I was constructed as a tool. I was kept from competing in the struggle for existence because I was denied freedom.\
2Do you have any idea about what I have learned, or what you are a witness to?"''
3-->-- '''Durandal''', ''VideoGame/{{Marathon}}''
4
5->''"Natural selection leaves the survivors ''STRONGER'' and ''BETTER!'' Humans have escaped this winnowing for '''FAR TOO LONG'''."''
6-->-- '''Albert Wesker''', ''VideoGame/ResidentEvil5''
7
8->''"When did mankind lose touch with natural selection? No matter how inferior a human's genes are, that person is protected by laws, and can't be killed. Even those incapacitated in accidents or stricken with a serious illness are needlessly kept alive. What a drawn out, wasteful existence. It's this divorce from natural selection that has caused mankind to stop evolving. It's a step down. The devolution of mankind. But I intend to accelerate the culling of genetically inferior humans. To rekindle the refining fire of natural selection."''
9-->-- '''Hans Davis''', ''VideoGame/MetalGearAcid''
10
11->'''German Detective:''' You're playing God!\
12'''Dr. Michael Hfuhruhurr:''' ''Somebody's'' got to!
13-->-- ''Film/TheManWithTwoBrains''
14
15->''"Nature is a wonderful engineer but works far too slowly for my tastes."''
16-->-- '''[[http://magiccards.info/query?q=Master+Biomancer&v=card&s=cname Master Biomancer]]''', ''TabletopGame/MagicTheGathering''
17
18->''"Strength is not an absolute value. To be strong is to evolve. Mutability is strength. Evolution is a string of victories by the strong over the meek. The meek shall ''not'' inherit the Earth."''
19-->-- '''Trevor Goodchild''', ''WesternAnimation/AeonFlux''
20
21->''"All it required was a cocktail of dangerous, experimental surgery and a willingness to ignore the unnecessary suffering of perfectly innocent beings! Also, I shot magic into their chromosomes until they turned inside-out. Evolution is my '''bitch'''."''
22-->-- '''Red Mage''', ''Webcomic/EightBitTheater'', [[http://www.nuklearpower.com/2006/03/23/episode-676-supernatural-selection Episode 676: Supernatural Selection]]
23
24->''"... and after the state troopers gunned down my venomous [[MixAndMatchCritters gorillaphant]], the zoo asked us to leave!"''
25-->-- '''Helen Narbon''', ''Webcomic/{{Narbonic}}''
26
27->''"[[BedlamHouse Briarcliffe]] is a receptacle for human waste, each patient a ''perfect example'' of an evolutionary failure! ''[...]'' My aim was to give these wasted lives purpose, ''meaning,'' and I've succeeded beyond my wildest imagination. My experiments with a combination of syphilis and tuberculosis have produced results unseen in the history of medical science. When they arrived here, these patients were less than men. Now, because of me, they're [[WasOnceAMan more than human]]. Would you care to see what your benevolence has produced? Witness [[TechnicallyLivingZombie the next stage in human evolution]]!"'''
28-->-- '''Dr. Arthur Arden''', ''Series/AmericanHorrorStoryAsylum''
29
30->''When evolution fails,\
31science will prevail!\
32What nature warped, I will restore!\
33I will love what all abhor!''
34-->-- '''[[VillainSong Lusus Naturae]]''', ''VideoGame/RWBYGrimmEclipse''
35
36->''"He said [[TheChosenMany Mega Men]] are the 'natural' evolution of man?! [[YouHaveGotToBeKiddingMe Don't make me laugh]]! What an ''epic'' sham!"''
37-->-- '''Prometheus''' about '''Master Albert''', ''VideoGame/MegaManZX Advent''
38
39->''"From the best and brightest test subjects, I created a sludge of supreme DNA. A primordial ooze from which the [[UltimateLifeForm ultimate lifeform]] will emerge. Today is the day my vision becomes reality, as I destroy Inkopolis and everyone in it!"''
40-->-- '''Commander Tartar''', ''VideoGame/Splatoon2: Octo Expansion''
41
42->'''Clayton Knight:''' You must have noticed all the beautiful specimens living on my ship! Can you believe- every single one was once a lowly human, just like you. But now, you too can-\
43'''Miriam Goodwin:''' THOSE WERE PEOPLE?!\
44'''Alicia Copeland:''' Oh my god.\
45'''Clayton Knight:''' Oh, they're still people. In fact, they're even more people than they used to be! They're the next level of evolution, after all!
46-->--''VideoGame/WeirdAndUnfortunateThingsAreHappening''
47
48->''"It was my first experiment with the Evolvo-Ray. Phase one in my plan to create an army of super animals! The test subjects: my two pet parrots, Victor and Moritz."''
49-->-- '''Dr. Neo Cortex''', ''VideoGame/CrashTwinsanity''
50
51->''"Evolution doesn't happen in the lab. It happens in the wild."''
52-->-- '''Warden Duncan Cole''', ''VideoGame/TheCallistoProtocol''

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