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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]?[[labelnote:*]][[WaxingLiyrical Where did you come from, Cotton-Eyed Joe?]][[/labelnote]] Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?

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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]?[[labelnote:*]][[WaxingLiyrical go]]?[[labelnote:*]][[WaxingLyrical Where did you come from, Cotton-Eyed Joe?]][[/labelnote]] Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?


Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]?[[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]] Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?

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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]?[[labelnote:*]]Where go]]?[[labelnote:*]][[WaxingLiyrical Where did you come from, Cotton-Eyed Joe?[[/labelnote]] Joe?]][[/labelnote]] Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?


* Creator/IsaacAsimov used this with regards to robots, of all beings, in the short story compilation/narrative ''[[Literature/IRobot I, Robot]]'', by comparing physically and [[ArtificialIntelligence positronically]] identical robots who developed with different frames of reference (generally resulting in [[InstantAIJustAddWater aberrant behavior]]).



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* In ''Fanfic/TheNewRetcons'' all [[spoiler:three]] of [[ComicStrip/ForBetterOrForWorse Elly Patterson's]] daughters wonder if they will eventually go mad like she had, or if their different upbringings and choices in life will help avoid that, as part of the reason she snapped was from her DarkAndTroubledPast [[spoiler:like giving Claire up for adoption after having a TeenPregnancy, or lying about Michael's biological father, or that the hell she suffered being a mom may be a SelfInflictedHell instead.]] What's worse, a letter from Aunt Phyllis hints [[spoiler:the madness is genetic, as there were other women with mental issues in Elly's mother's side of the family.]]

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* [[https://www.fanfiction.net/s/4292940/1/The-Power-He-Knows-Not The Power He Knows Not]] specifically states this as Dumbledore’s motive for sticking Harry with the Dursleys, trying to find out if it was his fault that the future Voldemort went bad or that Tom was bad to begin with. The experiment goes out the windows, however, when the spirit of Harry’s mother reveals herself to him on his fifth birthday, not that Dumbledore is aware of this, of course...


Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]][[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]]? Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?

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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]][[labelnote:*]]Where go]]?[[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]]? Joe?[[/labelnote]] Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?


Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]][[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]] ? Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?

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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]][[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]] ? Joe?[[/labelnote]]? Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?


Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]? Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?

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Everyone knows about some of the fundamental questions to life - [[Series/BabylonFive who are you, what do you want]], [[Anime/FullmetalAlchemist where did you come from, and where will you go]]? go]][[labelnote:*]]Where did you come from, Cotton-Eyed Joe?[[/labelnote]] ? Those are the "what" questions, but this is the "why". Why did you say that? Why did you do this? Why were you there?



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* Some ''Franchise/XMen'' fans have considered this debate when comparing the characters of Cable and Nate Grey, as each are essentially the same character in terms of their genetic heritage- being the 'child' of Scott Summers and Jean Grey, even if Nate was created in a lab using DNA samples stolen from his 'parents' while Cable was the naturally-conceived child of Scott Summers with Jean's clone- but experienced vastly different upbringings, with Cable a soldier dedicated to his chosen mission while Nate was intended as a weapon and resent others' attempts to use him.

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* RaiseHimRightThisTime


* ''Franchise/MetalGear'': A recurring theme in the series, Specifically in ''VideoGame/MetalGearSolid2SonsOfLiberty'', Raiden is contrasted with Solid Snake and his clone brothers. Whereas the Snakes are genetically altered clones of Big Boss, Raiden is a child soldier who was raised by Solidus (one of the Snakes) and then subjected into the [=S3=] Plan, a simulation program meant to train a soldier in Solid Snake's image.

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* ''Franchise/MetalGear'': ''VideoGame/MetalGear'': A recurring theme in the series, Specifically in ''VideoGame/MetalGearSolid2SonsOfLiberty'', Raiden is contrasted with Solid Snake and his clone brothers. Whereas the Snakes are genetically altered clones of Big Boss, Raiden is a child soldier who was raised by Solidus (one of the Snakes) and then subjected into the [=S3=] Plan, a simulation program meant to train a soldier in Solid Snake's image.

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* One of the themes in ''Literature/SurvivorDogs'' is whether Fierce Dogs are [[AngryGuardDog naturally violent]] or whether this is learned behavior. There are arguments on both sides. It's mentioned that the Fierce Dogs were [[BadPeopleAbuseAnimals beaten]] into being so cruel, but at the same time TokenHeroicOrc Storm is still a BloodKnight despite being HappilyAdopted at a few weeks old (mentally the equivalent of a 4-7 year old).


** During his DarkerAndEdgier interpretation, ''ComicBook/{{Superboy}}'' was all about this trope. Superboy is a clone created by human DNA that was altered and/or combined with Superman's DNA (DependingOnTheWriter). In the earliest years, his "daddy" was Paul Westfield and later, it was {{retcon}}ned to be Comicbbook/LexLuthor instead. Neither of them are very nice people. So, Superboy constantly questioned whether he was destined to become good or evil based on the genes provided by Superman or his human father.

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** During his DarkerAndEdgier interpretation, ''ComicBook/{{Superboy}}'' was all about this trope. Superboy is a clone created by human DNA that was altered and/or combined with Superman's DNA (DependingOnTheWriter). In the earliest years, his "daddy" was Paul Westfield and later, it was {{retcon}}ned to be Comicbbook/LexLuthor ComicBook/LexLuthor instead. Neither of them are very nice people. So, Superboy constantly questioned whether he was destined to become good or evil based on the genes provided by Superman or his human father.


* In ''[[https://www.fanfiction.net/s/4816968/1/Do-Not-Meddle-In-The-Affairs-Of-Wizards Do Not Meddle In The Affairs Of Wizards]]'', [[Franchise/HarryPotter Harry]]'s lawyer argues that the reason Dumbledore forced Harry to stay with the Dursleys was because he wanted to prove that it was nature, and not nurture, that drove an individual, and thus prove to himself that Tom Riddle would have gone bad, no matter what he did.

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* In ''[[https://www.fanfiction.net/s/4816968/1/Do-Not-Meddle-In-The-Affairs-Of-Wizards net/s/4816968/9/Do-Not-Meddle-In-The-Affairs-Of-Wizards Do Not Meddle In The Affairs Of Wizards]]'', [[Franchise/HarryPotter Harry]]'s lawyer argues that the reason Dumbledore forced Harry to stay with the Dursleys was because he wanted to prove that it was nature, and not nurture, that drove an individual, and thus prove to himself that Tom Riddle would have gone bad, no matter what he did.


* Basically the main conflict (besides the iconic "science versus technology") between the colours Green and Blue in ''TabletopGame/MagicTheGathering''. Green, [[{{Pun}} naturally]], favors Nature, believing in genetic fatalism and predestination. Blue's entire philosophy relies on the concept of ''[[BlankSlate tabula rasa]]'', and therefore it sides with nurture.

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* Basically the main conflict (besides the iconic "science "nature versus technology") between the colours Green and Blue in ''TabletopGame/MagicTheGathering''. Green, [[{{Pun}} naturally]], favors Nature, believing in genetic fatalism and predestination. Blue's entire philosophy relies on the concept of ''[[BlankSlate tabula rasa]]'', and therefore it sides with nurture.

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