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[[folder:Anime and Manga]]

* ''Manga/DrStone'': Discussed. When Senku hears about Ruri's chronic illness, he identifies it as something bacterial and decides to make a sulfate-based anti-bacterial. After months of work, they make the drug, and Senku finally gets a chance to diagnose Ruri directly, at which point he conclusively identifies her disease as pneumonia. He nearly cries in relief, because the sulfate drug works great against pneumonia, but there are plenty of other similar diseases that it wouldn't do anything to.

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** Soaps and alcohol break down the fatty membrane that encloses cells (incluiding bacteria), as well as many virii, literally disolving them away. Pathogens can evolve to survive targeted biochemical attacks to their lifecycle, but they cannot become immune to things that physically break them down.

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* In ''Literature/ManyWaters'', when Dennys is fighting a fever brought on by a combination of heatstroke and being thrown into a garbage pit with torn-up skin, he thinks back to the last time he'd had the flu, when he "had antibiotics to fight the fever". This is made even worse by the fact that his parents are scientists who ought to have known that flu is caused by a virus and can't be treated with antibiotics.


* ''[[SuperMarioBros Dr. Mario]]''. Thankfully, he has the cure.

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* ''[[SuperMarioBros Dr. Mario]]''.''VideoGame/DrMario''. Thankfully, he has the cure.


** Note: This doesn't apply to hand sanitizer. The active ingredient in most hand sanitizers is alcohol; your typical sanitizer is basically 80 proof vodka turned into a gel. [[CaptainObvious Almost needless to say]], we've been using alcohol to kill microbes for millennia (without realizing it for most of that time), and none of the critters has ever developed a resistance to ''that''. The same goes for bleach, ammonia, peroxide, and acid (none of which you should get on your hands!).

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** Note: This doesn't apply to hand sanitizer. The active ingredient in most hand sanitizers is alcohol; your typical sanitizer is basically 80 proof vodka turned into a gel. [[CaptainObvious Almost needless to say]], say, we've been using alcohol to kill microbes for millennia (without realizing it for most of that time), and none of the critters has ever developed a resistance to ''that''. The same goes for bleach, ammonia, peroxide, and acid (none of which you should get on your hands!).


** Sadly, this is far from a problem only in the developing world. Recent research in the UK, for example, showed that 48% of GPs had prescribed antibiotics to patients suffering from a common cold in the past year. Even in developed countries with socialised health care (where insurance companies and private payer demands are not important), antibiotic overuse is still a massive problem.

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** Sadly, this is far from a problem only in the developing world. Recent research in the UK, for example, showed that 48% of GPs [=GPs=] had prescribed antibiotics to patients suffering from a common cold in the past year. Even in developed countries with socialised health care (where insurance companies and private payer demands are not important), antibiotic overuse is still a massive problem.


* Sadly prevalent in real life medicine, as providers frequently don't want to wait to culture an organism before attempting to treat it. A major cause of the explosion in the rates and severity of multidrug-resistant bacterial infections. However, since a culture & sensitivity requires anywhere from one to five days to result and it looks [[{{Understatement}} kind of bad]] if your patient dies of his infection before the C&S report comes back, "empiric therapy" - prescribing a broad-spectrum antibiotic "cocktail" and narrowing it down when the C&S results - is common. This treatment is always prescribed in conjunction with a "pan culture" - culturing samples of the patient's blood, urine, stool, sputum, occasionally cerebrospinal fluid, and any wounds they might have, in order to pinpoint a source of infection. The classic example of this scenario is when someone is dragged into an ER unconscious, running a high fever and in apparent septic shock. They're dying, and you need to treat bacteremia immediately. What do you do? Bomb the infection with as broad-spectrum a cocktail as is reasonable, and hope the drugs kill the bugs before fatal damage results.

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* Sadly prevalent in real life medicine, as providers frequently don't want to wait to culture an organism before attempting to treat it. A major cause of the explosion in the rates and severity of multidrug-resistant bacterial infections. However, since a culture & sensitivity requires anywhere from one to five days to result and it looks [[{{Understatement}} kind of bad]] bad if your patient dies of his infection before the C&S report comes back, "empiric therapy" - prescribing a broad-spectrum antibiotic "cocktail" and narrowing it down when the C&S results - is common. This treatment is always prescribed in conjunction with a "pan culture" - culturing samples of the patient's blood, urine, stool, sputum, occasionally cerebrospinal fluid, and any wounds they might have, in order to pinpoint a source of infection. The classic example of this scenario is when someone is dragged into an ER unconscious, running a high fever and in apparent septic shock. They're dying, and you need to treat bacteremia immediately. What do you do? Bomb the infection with as broad-spectrum a cocktail as is reasonable, and hope the drugs kill the bugs before fatal damage results.


* In the last section of ''Literature/TheStand'', Stu Redman comes down with the flu. Tom Cullen, on the advice of his dead friend, finds some antibiotics and cures him. While Tom saving Stu's life is a CrowningMomentofHeartwarming, antibiotics don't cure the flu (a viral infection), and the antibiotics would be several months out of date, as it's after TheEndofTheWorldAsWeKnowIt.

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* In the last section of ''Literature/TheStand'', Stu Redman comes down with the flu. Tom Cullen, on the advice of his dead friend, finds some antibiotics and cures him. While Tom saving Stu's life is a CrowningMomentofHeartwarming, antibiotics Antibiotics don't cure the flu (a viral infection), and the antibiotics would be several months out of date, as it's after TheEndofTheWorldAsWeKnowIt.TheEndOfTheWorldAsWeKnowIt.

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** Sadly, this is far from a problem only in the developing world. Recent research in the UK, for example, showed that 48% of GPs had prescribed antibiotics to patients suffering from a common cold in the past year. Even in developed countries with socialised health care (where insurance companies and private payer demands are not important), antibiotic overuse is still a massive problem.

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* ''VideoGame/TheFlameInTheFlood'' lets you craft homemade antibiotics simply by roasting any two pieces of rotten food over a campfire. In some cases, it's preferable to deliberately let a wound get infected, since most food rots naturally over time, meaning you are almost guaranteed to have antibiotics or the ability to craft some compared to some more specific cures other injuries need.

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* In ''VideoGame/{{Cataclysm}}: Dark Days Ahead'', zombies can cause bite wounds, which require quick treatment or they will become infected wounds that cause all sorts of nasty penalties and eventual death. Fortunately, a single dose of antibiotics is enough to cure all infected wounds you have.

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** Also note that most soaps work on a much simpler concept: They make your hands slippery, making it easier to rub them under running water and thus shear the bacteria off your skin using mechanical force (which also, conveniently, is something many bacteria have yet to evolve resistance to). Statistically speaking, fifteen seconds of hand-rubbing under running water rubs ''enough'' bacteria off your skin that the survivors have a low chance of propagating in numbers enough to be infectious. So antibacterial soap does work... But not really much differently from regular soap.

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* Played straight in a ''Series/{{Sliders}}'' episode, where the protagonists end up in a world, where antibiotics were never discovered, and the nation is gripped by a deadly plague. Professor Arturo (a physicist!) manages to engineer a simple antibiotic from what he remembers in biology class, which is treated as a miracle cure.


** Choosing antibiotic therapy for as-yet unidentified infections poses yet another wealth of traps for the physician. For example, vancomycin, commonly used as a one-stop bug bomb for skin and soft tissue infections, is deadly to practically all Gram-positive organisms but practically no Gram-negatives. The choice of antibiotics for pneumonia changes quite a bit depending on whether the patient has recently spent time in a hospital or nursing home. Gastrointestinal organisms behave very differently in skin and soft tissue versus their home tract. The general wisdom is to treat with the most effective and narrowest spectrum antibiotic you can; when you don't know the specific infection's resistance, you make an educated guess as to which antibiotics should cover the most common causative organisms. (Hospitals are GenreSavvy to this, and one of the jobs of the hospital's infection control department is to create and publish an "antibiogram" - a comprehensive chart of the most common bugs in the community and which drugs they're sensitive and resistant to.)

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** Choosing antibiotic therapy for as-yet unidentified infections poses yet another wealth of traps for the physician. For example, vancomycin, commonly used as a one-stop bug bomb for skin and soft tissue infections, is deadly to practically all Gram-positive organisms but practically no Gram-negatives. The choice of antibiotics for pneumonia changes quite a bit depending on whether the patient has recently spent time in a hospital or nursing home. Gastrointestinal organisms behave very differently in skin and soft tissue versus their home tract. The general wisdom is to treat with the most effective and narrowest spectrum antibiotic you can; when you don't know the specific infection's resistance, you make an educated guess as to which antibiotics should cover the most common causative organisms. (Hospitals are GenreSavvy savvy to this, and one of the jobs of the hospital's infection control department is to create and publish an "antibiogram" - a comprehensive chart of the most common bugs in the community and which drugs they're sensitive and resistant to.)

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* In ''VideoGame/SevenDaysToDie'', curing a zombie infection doesn't even require antibiotics; you can just eat a jar of honey and be right as rain immediately, even if you're only one second away from keeling over dead...or undead, as the case may be.

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