History Main / MadScientistsBeautifulDaughter

* Literature/{{Prunella}} is helped by the witch's handsome son.
* ''Literature/SnowWhiteFireRed'':
** She regards herself as an ogress's daughter -- it's never explained whose daughter she is, if not -- but runs off with the prince.
** Similarly in ''Anthousa, Xanthousa, Chrisomalousa'', and in ''[[http://www.surlalunefairytales.com/rapunzel/stories/fairang.html The Fair Angiola]]'' where she's a foster daughter
** In ''[[http://www.mythfolklore.net/andrewlang/328.htm Geirlug The King's Daughter]]'', she helps him flee her stepmother.

* Since [[Characters/MarvelComicsMagneto Magneto]] is also a scientist, the Characters/ScarletWitch and her (on and off, currently on) half-sister ComicBook/{{Polaris}} qualify. Wanda looks [[UncannyFamilyResemblance almost exactly like her mother]].

* In ''VideoGame/TraumaTeam'', we have [[spoiler:Rosalia Rossellini, Professor Sartre's adopted daughter]].

** Talia Al-Ghul, the daughter of [[Characters/BatmanRasAlGhul Ra's Al-Ghul]]. Her loyalty to her father is... complicated. In the comics, it is usually unwavering. When she foils his [[spoiler:'destroy the written word' scheme]], a lackey shoots her in the leg; the lackey is soon fed to the lions. In the video game, ''VideoGame/BatmanArkhamCity'', it's played darkly [[spoiler:[[InTheBack when he makes a move of threatening Batman with her life]] if he does not kill him]]. This results her in leaving him [[spoiler:after Batman saves her]].

* Gender-flipped in ''ComicBook/TheKillersOfKrypton'': Znd'r Kol is [[EmperorScientist Empress]] [[BigBad Gandelo]]'s handsome adoptive son, who inevitably falls for ComicBook/{{Supergirl}}, much to his mother's anger.

* ''Franchise/WonderWoman'' [[ComicBook/WonderWoman1942 Vol 1]]: Gerta von Gunther plays with this trope, her mother Paula is definitely a MadScientist, and was a villain working for the Nazis when she first appeared but she was only working with the Nazis because they had Gerta and were threatening her life and Gerta is only old enough for her beauty to be evident years later after her mother switches sides out of gratitude when Diana saved Gerta. Gerta also turns out to be a MadScientist in her own right, but she's always kinder and more innocent than her mother.
* Laura "ComicBook/{{X 23}}" Kinney is this. Her creator, Dr. Sarah Kinney, was described as the foremost expert on mutant genetics and was hired by the Facility after her proposal to clone ComicBook/{{Wolverine}}. Despite the ethics of the project, Sarah's interest was purely ForScience, directly likening the idea of cloning a ''mutant'', when mainstream science had only ''just'' cracked cloning sheep and cats, to godhood. All this knowing full well that the child would be raised to be a LivingWeapon heading in. Laura herself is frequently described as Sarah's spitting-image (explained by some writers as Sarah using her own DNA to stabilize the sample taken from Wolverine), and it's made quite clear Laura is intended to be a quite beautiful young woman.

* The ''Series/{{Angel}}'' episode "[[Recap/AngelS02E06GuiseWillBeGuise Guise Will Be Guise]]", plays this straight - [[RecycledInSpace with MAGIC]]! In order to save [[DamselInDistress Cordelia]], [[NonActionGuy Wesley]] is [[MostDefinitelyNotAnImpostor forced to impersonate]] Angel and ends up playing bodyguard to an evil Warlock's beautiful daughter. HilarityEnsues.

* ''Series/TheTwilightZone1959'': In the episode "[[Recap/TheTwilightZoneS2E44TheLatenessOfTheHour The Lateness of the Hour]]", Jana is the pretty daughter of inventor Dr. William Loren, who has created an entire menagerie of [[RobotMaid robot servants]] to assist him and his wife, so much so that Jana is worried her parents are becoming overly dependent on the robots. She yearns to see the world outside, but her father is overprotective and [[GildedCage won't let her leave the house]]. Of course, in a true ''Twilight Zone''-style twist, [[spoiler:Jana finds out that she is merely another robot creation of her father's, albeit the most humanistic one he has ever made]].

** She's also a direct parody of [[Franchise/{{Batman}} Talia al Ghul]] (see above). Galasso decided to name Ethan his successor, and gave him Conquest as part of the deal. He went for it at the time, but later discovered that he is gay and refused to go through with it any more. Galasso didn't even seem to understand the concept, and then ordered Robin to impregnate Connie instead. For the record, Robin is a girl. Yeah, the jury's still out on how someone like Galasso managed to acquire a daughter to begin with.

** [[spoiler:Asami Sato is a case where she didn't ''know'' she was the daughter of a mad scientist who hid behind the image of a successful business owner that secretly supplies weapons and MiniMecha to the [[MugglePower Equalists]]. Even if her father had a strong FreudianExcuse for doing so, she is not happy to discover this]].
** [[spoiler:The leader of the Equalists, Amon/Noatak, is the TallDarkAndHandsome son of a Bloodbending mobster would-be mad dictator Yakone. The same goes for his younger brother, Tarrlok.]]

* In ''WesternAnimation/RickAndMorty'', Beth (the daughter of Rick and mother of Morty) is older than the typical example, but still qualifies. Much like Rick, she's smart, selfish, and an alcoholic, albeit to a lesser extent. She slips into the typical DaddysGirl, often giving Rick the benefit of the doubt and putting him ahead of other family members but isn't above calling him out when his antics are particularly {{JustForFun/egregious}}.

* Kitten from ''WesternAnimation/TeenTitans2003'' may [[AmbiguouslyHuman not even truly have been human]], seeing as her father was Killer Moth, and her [[DaddysLittleVillain beauty was clearly only skin deep,]] but given the nature of Killer Moth's schemes, she technically qualifies.

* Though not necessarily a bad guy, Dr. Orpheus from ''WesternAnimation/TheVentureBrothers'' is a mad scientist/necromancer with a relatively normal teenage daughter, Triana, whom he loves and cares for, humorously mixing his medieval, renaissance faire-like attitude with the trials of a modern-day single dad.

* This is the premise of tale type AaTh 428, "The Wolf" (after 2004, subsumed under new type ATU 425B, "Son of the Witch"): in Catalan and Italian variants, the heroine is helped by the witch's son, who is a normal human like the heroine.

* ''Anime/TenchiMuyo'':
** Ryoko, daughter of Washuu, is anything but cloistered or innocent. The mad scientist in question is her ''mother'', and Ryoko generally refuses to even admit they're related (even though the resemblance could hardly be more obvious) -- but she still falls for the hero.
** As it is, her mad scientist mother falls for the hero as well.
** Some adaptations of ''Tenchi'' do have Ryoko rather scared of her [[AbusiveParents mother]] because she likes [[GuineaPigFamily using her as a guinea pig.]]
** Mihoshi is the mad scientist's great-grandaughter.
* ''Anime/SailorMoon'':
** Professor Souichi Tomoe, the MadScientist of the third season, has a beautiful young daughter named Hotaru. Who actually happens to be a) possessed by Mistress 9, the season's [[TheDragon Dragon]], and b) unknown even to herself until the end, the heroic MagicalGirl Sailor Saturn. (Oh, and she's also about twelve years old. Most of the time. And in the [[Manga/SailorMoon manga]], a {{cyborg}}. She becomes fully human later, though.)
** Hotaru is a slight subversion as she's only around 12 when she's introduced; her being reborn as an infant and later growing up to around this age, but appearing younger (possibly due to a change in art style in the last season) complicates her real age. However when she's possessed by Mistress 9, her body grows up into a beautiful young woman.
* In the continuities where Juuzo Kabuto is crazier, Kouji Kabuto from ''Anime/MazingerZ'' fits as the Mad Scientist's Cute Grandson.
** Lorelei -- a secondary character from ''Anime/ShinMazinger'' whom Shiro got a crush on -- also fits.
** Lisa, on the other hand, subverted it. Her father -- Professor Gordon -- was completely sane.
* In ''Anime/RomeoXJuliet'', [[DefectingForLove Romeo Condore Van diMontague]] is the son of the dictator of Neo Verona, the ruthless Leontes Montague, as well as the love interest of Juliet Fiamatta Errs diCapulet, the long-lost heiress of the Capulets. [[spoiler:Actually, there are '''two''' Mad Dictator's Handsome Sons: one is Romeo and the other is [[AloofBigBrother his half-brother Tybalt]], who is still Juliet's cousin since his mom was a Capulet. Or '''three''', if we count Mercutio...]] Dude, that's one messed-up family tree.

* ''Manga/FrankenFran'':
** Made more of in the manga. Madaraki Fran is certainly the beautiful daughter of Dr. Madaraki, for a given value of [[CuteMonsterGirl "beautiful"]], and for a given value of [[ArtificialHuman "daughter"]]. She actually [[MadScientist takes after her father]] and generally (almost) [[HalfHumanHybrid everything]] [[BodyHorror that happens]] [[MultipleHeadCase in the manga]] is her fault.
* In ''Manga/DGrayMan'', the ActionGirl Lenalee Lee is the younger sister of Mad Scientist Komui, [[PromotionToParent who raised her]]. Being an active fighter of evil, Lenalee isn't exactly sheltered, but her brother's attempts to [[BigBrotherInstinct protect]] her [[StealthPun Innocence]] is [[KnightTemplarBigBrother the stuff of legends]]; i.e., [[HeavySleeper When all other attempts have failed]], he is [[RunningGag usually]] woken up by being told that Lenalee is getting married, which causes him to immediately wake up and starts freaking out about it.
* Ennis of ''Literature/{{Baccano}}'', creation and "daughter" of the 1930 arc's BigBad, Szilard. She does twist it slightly in that [[spoiler:she betrays him not for TheHero, Firo (who, at that point, she thought was dead), but for the [[PluckyComicRelief comic]] OutlawCouple, Isaac and Miria]]. There's also the daughter of MadScientist and unapologetic ManipulativeBastard Huey Laforet, Chane Laforet, who falls in love with the AntiHero and professional assassin, Claire Stanfield. This ends up being subverted in that [[spoiler:Chane doesn't betray her father for him - instead, Huey just hires Claire]].

** Asuka. Beautiful? Check, Smart? Check, Love Interest? Check, Loves MadScientist mother dearly? Check. Mother is insane? Check ([[spoiler:Unless you call: A) Reattempting an experiment that ATE the previous person. B) hanging yourself (After losing what sanity you had in said experiment) so that your daughter would be the first person to find your body. Sane]])

* ''Manga/GetterRobo'''s Michiru counts as this in several continuities.

* ''Manga/SoulEater'': Medusa's [[AmbiguousGender child]] Chrona [[spoiler:joins the heroes, albeit unwillingly at first. They become affectionate towards Maka, and to a lesser extent the other protagonists, but are kidnapped back and driven (more) insane. They do eventually betray Medusa, but remain an antagonist until the end of the series]].
* ''Manga/FullmetalAlchemist'': Riza Hawkeye is the Crazy Alchemist's Beautiful Daughter.
** Not to mention Nina. Sure, she is just five and anything but a love interest to the heroes, but she is cute, adorable, adores her State Alchemist Dad who shelters her [[spoiler:and maybe would have grown into a very cute young woman if her father hadn't used her for chimera experiments that ultimately doomed her]].

* ''Literature/{{Durarara}}'' has Shinra as the Mad Doctor's Handsome Son. He's... slightly more normal than his father Shingen, but he didn't get away without a screw or two loose.
* Minato Sahashi is a male example, in ''Manga/{{Sekirei}}''. His mother is the head scientist of the Sekirei Plan, and leaves him innocent and oblivious to her work, as well as the identity of his father. [[spoiler:It is, of course, BigBad Minaka]]. Higa mistakenly believes the younger Sahashi sibling, Yukari, to be this as well. She's [[DaddysLittleVillain not]], and sets fire to his penthouse on her way out.
* ''Manga/Cyborg009'':
** Dr. Isaac Gilmore is child-less, and he subverts this by gaining the Cyborgs as his adoptive children ''after'' he stops being a MadScientist. [[spoiler:And there's the little detail that he was among the {{mad scientist}}s who ''created the cyborg team'' [[TheAtoner in the first place]].]]
** Also subverted by Cynthia Findor, since her father ''is'' doing really crazy experiments [[ReluctantMadScientist but NOT willingly]]. In fact, Black Ghost kidnapped ''her'' to reinforce their intentions to keep Dr. Findor under their thumb.
* ''Anime/KillLaKill'': Subverted with Ryuko, since her father Isshin was a perfectly sane man and the BigGood of the story, despite his eccentric appearance. [[spoiler:Double Subverted when it's shown that her mother is [[KnightOfCerebus Ragyo]], who experimented on and threw her away as a child]]. [[spoiler:This also means that Satsuki counts, as well]].
* ''Anime/{{Boruto}}'': [[spoiler:It turns out that Mitsuki is the Mad Scientist Orochimaru's Handsome Son. Mitsuki says he respects his parent, but thankfully, doesn't seem to have inherited Oro's twisted personality and madness]].
** It also turns out that [[spoiler:Sumire]] is the daughter of a Mad Scientist who had been a loyal follower of Danzo, and brainwashed her into being his TykeBomb to destroy Konoha in revenge for the destruction of ROOT.

* Anime/{{Ponyo|OnTheCliffByTheSea}} is the prepubescent form of this: a Mad Sorcerer's Adorable Daughter.
* ''Manga/MadeInAbyss'' has Prushka, [[spoiler:the adoptive daughter of the White Whistle Bondrewd the Novel]]. Unlike most examples, her awareness of her father's actions is fairly significant. The degree of isolation that she lives in is enough for her to be incapable of seeing anything wrong with it, though, [[spoiler:to the extent of seeing the failed Praying Hands as a tragic necessity and being unbothered when she discovers her father's [[PoweredByAForsakenChild Cartridges]] ]].
* In ''Manga/{{Bleach}}'' we have Nemu, the daughter of MadScientist Mayuri Kurotsuchi, who is quite calm and nice despite her oddities, unlike her dad. For bonus points, Nemu doesn't have a mother, she was created by Mayuri from his own genetic material, making her his opposite sex clone as well as his daughter.
* In ''Anime/GaoGaiGar'', Guy is the mad scientist's handsome son in this case. He is the son of GGG's lead inventor and got his good looks from his deceased mom. When he was near death, his father managed to save his life using classified military technology, transforming 95% of his body into a cyborg.

* ''ComicBook/{{Shazam}}'':
** Doctor Sivana, nemesis of Captain Marvel, has a daughter with the painfully obvious name "Beautia"; naturally she sides with the Captain against her father.
** In this case Sivana also has a good/handsome son ''and'' an evil/ugly daughter and son, who are perfectly happy to help their dad go up against Captain Marvel.
** Though in more modern works, his handsome son and daughter are portrayed as self-centered, spoiled brats while his ugly, brilliant children are their mother's [[TheUnfavourite un-favorites]] and running their own experiments just to impress their mostly absent father.

* The Yellow Claw, a Creator/MarvelComics CaptainErsatz for Literature/FuManchu, had a Beautiful Grandniece, who repeatedly betrayed him due to her love for FBI agent [[ComicBook/AgentsOfAtlas Jimmy Woo]]. Eventually, he put her in [[HumanPopsicle suspended animation]] until he could fuse her soul with that of a suitably power-mad Egyptian princess. Really.
* Sorta done in ''ComicBook/WerewolfByNight''. When traveling to an island for a cure for his werewolfism, Jack meets the local mad scientist Miles Blackgar and the beautiful daughter Marlene. Marlene helps Jack at first and doesn't even fear him when he's in wolf form, but after he knocks out her father she [[spoiler:turns out to have a Gorgon gaze and turns Jack to stone for grabbing her arm]]. She also seems to help Jack more out of self preservation, since she mentions that her father ultimately intended to experiment on her, [[spoiler:to cure her gaze of stone]].

* Laura "ComicBook/{{X 23}}" Kinney is this. Her creator, Dr. Sarah Kinney, was described as the foremost expert on mutant genetics and was hired by the Facility after her proposal to clone ComicBook/{{Wolverine}}. Despite the ethics of the project, Sarah's interest was purely ForScience, directly likening the idea of cloning a ''mutant'', when mainstream science had only ''just'' cracked cloning sheep and cats, to godhood. All this knowing full well that the child would be raised to be a LivingWeapon heading in. Laura herself is frequently described as Sarah's spitting-image (explained by some writers as Sarah using her own DNA to stabilize the sample taken from Wolverine), and it's made quite clear Laura is intended to be a quite beautiful young woman.
* Dr. Zabo/Mr. Hyde doesn't have much in the looks department (and his inside matches is outside), which is probably why he frequented prostitutes. His daughter, [[Characters/SHIELDDirectors Daisy Johnson/Quake]] is consistently described as gorgeous, and is one of ComicBook/{{SHIELD}}'s real lookers, and can't seem to do anything in civilian mode without someone hitting on her.
* Linea in ''ComicBook/WarlordOfMars'' is a Black Martian noblewoman whose father is a mad priest of Issus that wants to activate a DoomsdayDevice that will wipe out all life on Mars (since the defeat of their people at the hand of the Red Martians, he would rather destroy the planet than let themselves be ruled by lesser races). It's revealed that [[spoiler:her grandmother was Issus herself, and she qualifies as a Mad Goddess' Beautiful Granddaughter too]].

* ''Franchise/WonderWoman'' [[ComicBook/WonderWoman1942 Vol 1]]: Gerta von Gunther plays with this trope, her mother Paula is definitely a MadScientist, and was a villain working for the Nazis when she first appeared but she was only working with the Nazis because they had Gerta and were threatening her life and Gerta is only old enough for her beauty to be evident years later after her mother switches sides out of gratitude when Diana saved Gerta. Gerta also turns out to be a MadScientist in her own right, but she's always kinder and more innocent than her mother.

* ''ComicBook/{{Metamorpho}}'': Simon Stagg is a mad scientist and CorruptCorporateExecutive, while his daughter Sapphire is explicitly a ''very'' beautiful woman. Part of the fuel for Rex Mason's desire for a cure is because he can't believe a woman as beautiful as her could ever love a man as disfigured as him. [[SugarWiki/HeartwarmingMoments She can.]]
* Gender-flipped in ''ComicBook/TheKillersOfKrypton'': Znd'r Kol is [[ScientistEmperor Empress]] [[BigBad Gandelo]]'s handsome adoptive son, who inevitably falls for ComicBook/{{Supergirl}}, much to his mother's anger.

* Literature/{{Prunella}} is helped by the witch's handsome son.
* ''[[Literature/TheTrollsDaughter The Troll's Daughter]]'': The troll has a lovely daughter who he keeps in an undersea castle to keep anyone from taking her away. She has grown tired of it and plots with the hero to gain her freedom.

* From ''Franchise/DespicableMe'', we have the cutest daughters: Margo, Edith, and Agnes.
* ''WesternAnimation/GrooveSquad'' has the character, Star, who turns out to be the daughter to evil MadScientist, Dr. Nightingale. While he looks like a cartoony villain, Star is an attractive redhead who's more "high school evil" rather than "regular evil". Her mother is never seen, but Star probably got her looks from her.

* The two Literature/FuManchu films to feature the scientist having a daughter:
** ''Film/TheMaskOfFuManchu'' has the canonical Fah Lo See. Although Fu Manchu refers to her as 'ugly', she's played by classic beauty Creator/MyrnaLoy.
** ''Daughter of the Dragon'' likewise has screen beauty Creator/AnnaMayWong as Princess Ling Moy.
* In ''Film/TheIslandOfDrMoreau1996'', they give the title doctor a beautiful cat-woman daughter -- who conveniently slides into love interest for the hero Douglas.
** ''Film/IslandOfLostSouls'' started the cat-woman daughter of the mad scientist.
* As [[Film/TheRockyHorrorPictureShow the song]] goes, "Anne Francis stars in ''Film/ForbiddenPlanet''", based on ''Theatre/TheTempest'', as Altaira, the Beautiful Daughter of the Mad Scientist, Dr. Morbius.
** Actually a semi-aversion, though, since Morbius specifically denies being a mad scientist, and is ultimately proven to be misguided rather than crazy.
* Occasionally appearing in a ''Franchise/{{Godzilla}}'' movie as well, most notable being Katsura from ''Film/TerrorOfMechagodzilla'', cyborg daughter of Dr. Mafune. Also, it is worth mentioning that Emiko Yamane, heroine of the original ''Film/{{Go|dzilla1954}}jira'' film, was TheProfessor's daughter.

* Freder Frederson of ''Film/{{Metropolis}}'' is a Slightly Unhinged Dictator's Handsome Son. Incidentally, the MadScientist was in love with Freder's mom.
* In ''Film/{{Willow}}'', Sorsha plays the Mad Sorceress's Beautiful Daughter. With some help from a LovePotion and her mother she performs a HeelFaceTurn.

* ''Film/Blade1998'': One of the vampire scions helps bring down her house.
* Helen Kokintz in ''Film/TheMouseThatRoared'', except that her father is not mad, just a bit eccentric.
* Nanelia in ''Film/BattleBeyondTheStars'', though her father is senile rather than megalomaniacal. He wants the hero to stay and mate with his daughter instead of running about trying to recruit TheMagnificentSevenSamurai to defend his planet. Fortunately Shad convinces Nanelia to escape with him, whereupon they have the requisite romance.
* Dione, the daughter of Melanthius in ''Film/SinbadAndTheEyeOfTheTiger'' is an example of the daughter of a good scientist. And he is not really mad, just a little batty.
* Kyra in ''Film/SinbadOfTheSevenSeas'' is the daughter of the CloudCuckooLander inventor and "wizard" Nadir, and ends up as Sinbad's {{Love Interest|s}}.
* ''Film/YoungSherlockHolmes''. Professor Waxflatter is more eccentric than mad, but his daughter is quite beautiful.
* In the [[WhatCouldHaveBeen/SpiderMan cancelled]] ''[[Film/SpiderManTrilogy Spider-Man 4]]'', Peter was going to end up in a DatingCatwoman relationship with [[Characters/BlackCatMarvelComics Felicia Hardy]], who in this continuity was also the daughter of the Vulture.
* The learned Rabbi of the silent movie ''Film/TheGolem'' has his beautiful daughter Miriam, who promptly falls in a forbidden love with the Christian Knight Florian. Their romance turns out to be a RedHerringTwist, though.
* Amy Szalinski in ''Film/HoneyIShrunkTheKids'' is an example of the daughter of a good guy mad scientist, Wayne Szalinski. However, she's not an only child, as she has a younger brother, Nick, and the sequels include another younger brother named Adam. She is, however, the only girl.

* In the 1986 Ozploitation thriller ''Film/TheBigHurt'', a woman enlists an IntrepidReporter to prove her research scientist father was murdered by a GovernmentConspiracy. [[spoiler:It turns out that her father is very much alive and part of the conspiracy, to develop a mind-control drug, and she ends up killing him for real.]] Ironically the daughter has herself spent time in a mental institution, diagnosed as paranoid for insisting her father was murdered.
* ''Film/TheShadow'': Margo Lane is Dr. Reinhardt Lane's daughter. " ''This'' is green...''that's'' red!"

* ''Film/TopSecret'': Nick's primary love interest is Hillary, a beautiful German woman who's associated with LaResistance. Her goal is to free her father Dr. Nicholas Flammond, a scientist who was kidnapped by the [[CommieNazis East German military]] and forced to build a doomsday weapon.
* ''Film/TwiceToldTales'': In "Rappaccini's Daughter" (adapted from the Creator/NathanielHawthorne short story described in Literature below), Giacomo Rappaccini (Creator/VincentPrice) keeps his daughter Beatrice in a garden. A university student next door, Giovanni, sees her and falls in love. One of Giovanni's professors says that he used to teach with Rappaccini. Many years ago, Rappaccini abruptly quit academia and became a recluse after his wife ran away with a lover. Rappaccini has treated Beatrice with an exotic plant extract that makes her touch deadly; he does this to keep her safe from unwanted suitors, but it makes her a prisoner in her own home.

* The above two comic book examples both draw elements from Sax Rohmer's ''Literature/FuManchu'' mythos, including the Beautiful Daughter; however, Fu's own daughter Fah Lo Suee was a full-fledged FemmeFatale (or even [[TheVamp Vamp]]) rather than a cloistered innocent -- just as likely to turn against him, but because she wanted to take his job....
* A LampshadeHanging: in Creator/RobertAHeinlein's novel ''Literature/TheNumberOfTheBeast'', Deety Burroughs introduces her father and herself to her future husband Zeb Carter by declaring, "He's a Mad Scientist, and I'm his Beautiful Daughter." Zeb, in his role as the {{Narrator}}, comments immediately on the cliché.
* In "Literature/RappaccinisDaughter", Beatrice is Giacomo Rappaccini's daughter. She's as beautiful and radiant as he's withered and unsettling. Giacomo Rappaccini's area of expertise are plant-based poisons and he's cultivated several new species just to get new poisons. Even Beatrice is subject of his experiments.
* Though Sloan from the ''Literature/InheritanceCycle'' is more JerkAss than BigBad ([[spoiler:though he does betray his village in Book 2]]), his daughter Katrina might count.%%How? Sloan isn't a mad scientist at all.
* Creator/PhilipJoseFarmer gleefully inverted this trope with "The Beautiful Scientist and her Mad Daughter."
* Children's author Allan Ahlberg wrote a notably creepy poem called ''The Mad Professor's daughter''.

* ''Literature/TheFirstLaw'' plays this straight with Bayaz and Tolomei. [[spoiler:Then, in a brutal twist, it is revealed that Bayaz was the one who threw her from the tower, not her MadScientist father, in order to hold a monopoly over the secrets which she possessed.]]
* The heroine of Creator/EdgarRiceBurroughs's ''Literature/TheMonsterMen'' is the daughter of a mad scientist who is producing the title Monster Men -- he hopes to marry her off to one. (He gets better, though.)

* In ''Literature/ASongOfIceAndFire'' [[TheCaligula King Aerys]] managed to beget a ridiculously good offspring (well, if you don't mind Viserys' mental health). Rhaegar was always in the collective imagination (don't mind [[{{Archenemy}} Robert Baratheon]]) the Mad King's handsome and noble son, who'd have made a great king some day. Daenerys is also a bright young woman who before hitting 16 is already considered the WorldsMostBeautifulWoman and tries hard to not make the same mistakes her family did.
* Elizabeth Faulkner, the daughter of an irrational Elizabethan steam-engineer, in ''Phra the Phonecian'' by Edwin Arnold.
* Georgette Cuvelier in Harry Dickson's Adventures. The young woman turns out to be the daughter of [[spoiler:Pr Flax]], a former archenemy of the hero. Played straight in that she has a huge crush on Harry Dickson. Subverted in that [[spoiler:she remains evil and would rather avenge her father and die than surrender]].
* Angie Mitchell in Creator/WilliamGibson's ''Literature/SprawlTrilogy'', particularly in ''Literature/CountZero''.
* [[PlayingWithATrope Played with]] in Theodora Goss's short story [[http://strangehorizons.com/2010/20100118/daughter-f.shtml "The Mad Scientist's Daughter,"]] which also namedrops a who's who of iconic [[MadScientist Mad Scientists]] in fiction.
** The short story was later expanded into a series ''Literature/ExtraordinaryAdventuresOfTheAthenaClub''

* In the short story "The Girl of My Dreams" by Hilary Ayer (a crossover between the ''Torg'' and ''TabletopGame/{{Paranoia}}'' roleplaying universes), this is not just a trope, but a law of nature.
-->'''Professor Thistlebottam:''' I was a Scientist, therefore I had to be either Sinister or Mad. I seem to have been cast as Mad, therefore by the laws of the cosm, I had to have a Beautiful Daughter.
* In ''The Bride of the Wind'', the eponymous character's father was a scientist, and she said to be beautiful, if unique-looking.
* In one of the ''Schaduw'' (Shadow) detective/policiers by Havank, a Dutch writer, the eponymous main character encounters the most beautiful young woman he's ever seen. As this happens in a remote castle somewhere in Normandy, she can't be anything but a MadScientist's daughter. The guy has engineered spiders to be a bit bigger and powerful (the biggest eats a grown pig in a couple of seconds), but he's disappointed their brains have not kept up. But now this human brain has come walking in ... perfect. The kicker: he's named his daughter [[UnfortunateNames Aranea]] (could have qualified as a MeaningfulName, but she herself tries to keep herself away from his shenanigans).
* Miranda Taligent from the SteamPunk novel ''Literature/TheDreamOfPerpetualMotion''. She eventually goes mad herself.

* Invoked in Creator/GeneWolfe's "The Last Thrilling Wonder Story": the author is deliberately writing a pulp story, so ''of course'' the scientist has a beautiful daughter, and the protagonist knows he will love her before they even meet.
* Subverted in ''Literature/DieAlchimistin''. Aura Institoris is certainly beautiful, and kept cloistered in her castle and then at the institute at her father's wish, and her father in an alchemist who is most definitely not all there, and she is (in the beginning) his favorite child, but [[spoiler:it turns out that he was maintaining their bond and keeping her away from theyo turns out that Aura's mother was her father's daughter as well]].
* ''Literature/TheStarchildTrilogy'': In ''The Reefs of Space'', Donna Creery is the daughter of the Planner of Earth, chief executive of the [[MasterComputer computer-controlled]] dictatorship which rules Earth, but she's sympathetic to Steve Ryeland, the scientist who's been arrested for reasons he doesn't understand. She eventually helps him escape when he ends up facing a death sentence.
* In Fyodor Sologub's ''The Poisoned Garden'', the Professor's daughter, only called the Beauty, is an example. He uses her to lure young men into his garden and poison them in revenge for his ancestor's death.
* The title institution of ''Literature/TheSecretsOfDrearcliffGrangeSchool'' is basically a finishing school that turns mad scientist's beautiful daughters into femmes fatales to help them snag a good superhero (or villain) husband. While the viewpoint character ''isn't'' this trope, many of the other students have diabolical masterminds as parents.

* This is expanded in the ongoing ''Narbonic'' roleplay ''Roleplay/TheMadScientistWars'', where Jane Narbon is the (incredibly beautiful) daughter of Helen Beta and Dave. In addition to being TheVamp, she's also (yup) [[MadScientist Mad]].
* Subverted in the forum roleplay ''Roleplay/TheMadScientistWars''. The concept is reimagined as the "Mad Scientist's Beautiful Daughter ploy", in which the daughter will ''always'' pretend to help the hero escape, then drop him into some even nastier bit of trouble. Apparently, it's hard on the heroes and fun for the daughters.

* Odile from ''Theatre/SwanLake''. Daughter of the evil sorcerer, he sent her to seduce the hero.

* From ''VideoGame/PokemonBlackAndWhite'': [[spoiler:N. Let's see: Mad dictator for father? Check. Only son? Check. (If they are related at all...) Beautiful? [[{{Bishonen}} I think we can let the fangirls field this one]]. Innocent? His views about the relations between Pokemon and Humans are certainly naive. Late teens? Check. Loves his father dearly? Unfortunately. Kept cloistered from the rest of the world? Oh yeah, to the point where much of Ghetsis' plan revolved around the way this would warp his views! Sometimes has doubts about his methods? He certainly starts to question himself after hearing the PC's Pokemon talk. Falls in love with the hero/heroine? Well...something like that, anyway. At the very least, he comes to see the PC as a friend. Betrays his father? Not until said father has already revealed himself as a monster, so that's a no, but otherwise, N has this trope ''covered'']].
* ''[[VideoGame/{{Twinbee}} Pop'n Twin Bee]]'' has Dr. Murdock and Madoka

* [[spoiler:Marta]] in ''VideoGame/TalesOfSymphoniaDawnOfTheNewWorld''.

* Tabitha in ''Webcomic/FarOutThere'' is not only a [[https://web.archive.org/web/20151025012644/http://faroutthere.smackjeeves.com/comics/1794321/page-566-just-keep-doing-what-youre-doing/ looker]], but followed her Daddy's footsteps into being a MadScientist herself.

* Jadis Diabolik of the ''Literature/WhateleyUniverse'', in her first (chronological) appearance, even [[LampshadeHanging references this trope]]. It's one of her [[BerserkButton hot buttons]] that she's the daughter of the [[WellIntentionedExtremist infamous mass murderer]] [[MadScientist Dr. Diabolik]], and she has the Exemplar superpower, but she's isn't actually beautiful - she's plain, and elsewhere would be considered moderately attractive, but compared to all the other Exemplars running around, she feels incredibly ugly (plus, it hasn't been stated for certain that she is an Exemplar or if something her father did just mimics the effects). She is [[ACupAngst particularly sensitive]] about not having the MostCommonSuperpower, which is almost universal in female Exemplars (at lest those who don't get a BodyHorror result instead). Despite this, she did have a guy vying for her attention after she saved him from a smalltime super villain thug, and two others at Whateley (though one's a creep who imagines himself to a Franchise/{{Batman}}-esque ByronicHero, and the other just wants favours from her father and the parents of the other Bad Seeds).
* ''Website/GaiaOnline'''s Gino Gambino might be a [[DudeLooksLikeALady dude]], but he otherwise fits this trope.

* Though a departure from her portrayal in the comics, Lorna Dane a.k.a. Polaris is made into something of a Mad Scientist's beautiful daughter in ''WesternAnimation/WolverineAndTheXMen2009''. She, unlike her siblings, is intentionally kept innocent and naive of the reality of the society her father (Magneto) created on Genosha. And in one episode she falls for Gambit who, [[AntiHero while his status as a hero may be suspect]], is the enemy of her father (in that [[GentlemanThief he plans to steal from him]]).
* Subverted in ''WesternAnimation/CaptainPlanetAndThePlaneteers'', as the mad scientist Dr. Blight was an attractive woman, and as a result her beautiful daughter Betsi [[StrongFamilyResemblance looks exactly like her]].
* Aelita from ''WesternAnimation/CodeLyoko'', though her father's sanity is more questionable than definitely not present.
* Bonnie Lepton in the ''WesternAnimation/BuzzLightyearOfStarCommand'' episode "Eye of the Tempest", the [[SheIsAllGrownUp All Grown Up]] daughter of a former Star Command scientist who became [[WithGreatPowerComesGreatInsanity mad after experimenting on himself]].
* Inverted on ''WesternAnimation/{{Gargoyles}}'': Halcyon Renard, while cynical and not without his flaws, is a strongly principled scientist. His beautiful daughter, Fox, is an amoral mercenary who even marries his equally amoral business rival.

* {{Subverted|Trope}} in ''WesternAnimation/SpyGroove'' with Sierra Nevada, the daughter of a mad robotics genius/casino owner. Turned out ''she'' was the mad genius; daddy was just a robot she built to draw attention away from her while she played this trope to the hilt to fool do-gooders.
* The second season of ''WesternAnimation/JonnyQuestTheRealAdventures'' not only brought back the Quests' arch-nemesis Dr. Zin, it also gave him two daughters, Anaya and Melana, one whom becomes romantically involved with Hadji.

* In ''WesternAnimation/DannyPhantom'', Jazz definitely takes after her mother. Even when she won't admit it ''and'' when [[GeniusDitz Jack Fenton is more bumbling than mad]].
* ''WesternAnimation/TheLegendOfKorra'':
** [[spoiler:Asami Sato is a case where she didn't ''know'' she was the daughter of a mad scientist who hid behind the image of a successful business owner that secretly supplies weapons and MiniMecha to the [[MugglePower Equalists]]. Even if her father had a strong FreudianExcuse for doing so, she is not happy to discover this]].
** [[spoiler:The leader of the Equalists, Amon/Noatak, is the TallDarkAndHandsome son of a Bloodbending mobster would-be mad dictator Yakone. The same goes for his younger brother, Tarrlok.]]
* Farmer Brown from the ''WesternAnimation/BatmanTheAnimatedSeries'' episode "[[Recap/TheNewBatmanAdventuresE14Critters Critters]]" can count as a Mad Scientist, seeing as he's using microbiology to create monstrous farm animals, and he does indeed have a beautiful daughter named Emmylou. She's also his enforcer and is ''much'' stronger than her almost petite frame would appear, being more than a match for Batgirl. (She claims that it's due to beef steroids, clearly another of her dad's experiments.)
* In ''WesternAnimation/SkysurferStrikeForce'', Cerina is the daughter to show BigBad, Cybron. Unlike most of the examples though, she's clearly evil.
* Julie Kane in ''WesternAnimation/{{Motorcity}}''. Abraham Kane's technically not a mad scientist, but she still fits the trope. She also kept it a secret, fearing her friends will think she's just like him.
* Dr. Vahtoss and his daughter Carmelita from ''WesternAnimation/TheTick''.
* ''WesternAnimation/Ben10'' invokes this with Attea, daughter of Emperor Milleous. Her father has her carefully watched, but she [[spoiler:manages to betray him, fall for the hero (when he's the same species), and take over daddy's empire]] over the course of a [[TwoPartEpisode two-parter]].
* In ''WesternAnimation/RickAndMorty'', Beth (the daughter of Rick and mother of Morty) is older than the typical example, but still qualifies. Much like Rick, she's smart, selfish, and an alcoholic, albeit to a lesser extent. She slips into the typical DaddysGirl, often giving Rick the benefit of the doubt and putting him ahead of other family members but isn't above calling him out when his antics are particularly {{JustForFun/egregious}}.
* ''WesternAnimation/TransformersAnimated'': Isaac Sumdac is a pudgy, elderly roboticist with beady, sunken eyes. Meanwhile, his daughter Sari is an adorable little girl with big eyes. Aside from sharing his skin tone, she looks absolutely nothing like him. [[spoiler:One could justify it by saying their lack of resemblance is because Sari [[RobotGirl isn't human]], but it is confirmed within the show that she shares his DNA.]]

* From ''WesternAnimation/DespicableMe'', we have the cutest daughters: Margo, Edith, and Agnes.

** Her name is Conquest (Connie for short), and the phrase AnythingThatMoves hardly does her justice. She is known for giving out sex "free with purchase", any purchase, at her father Galasso's toy store. Nevertheless, he seems to be under the impression that she is a virgin, even though he has continually forced her to copulate with anyone he considers capable of producing a (male) heir for him. There's even mention of a time he witnessed a heroic horse, and tried to [[{{Squick}} use her to breed centaurs]]. Despite having a head full of air and a high libido, she is surprisingly canny and eventually rebelled against her tyrannical father, and is now apparently one of his main business rivals. She's still a tramp, though, and considers a tryst with one of Galasso's more attractive male employees a suitable substitute for a briefcase full of cash as a bribe.

* Andre Caroff's ''Madame Atomos'' was a vengeful scientist with a hard-on for radioactive zombies and madness beams. She [[CloningBlues created a younger version of herself]] named Mie as a backup plan, who promptly turned on her after falling for Atomos's nemesis, Smith Beffort of the FBI.

* Inverted on ''WesternAnimation/{{Gargoyles}}'': Halcyon Renard, while cynical and not without his flaws, is a strongly principled scientist. His daughter, Fox, is an amoral mercenary who even marries his equally amoral business rival.

* In ''Anime/RomeoXJuliet'', [[DefectingForLove Romeo Condore Van diMontague]] is the son of the dictator of Neo Verona, the ruthless Leontes Montague, as well as the love interest of Juliet Fiamatta Errs diCapulet, the long-lost heiress of the Capulets. [[spoiler: Actually, there are '''two''' Mad Dictator's Handsome Sons: one is Romeo and the other is [[AloofBigBrother his half-brother Tybalt]], who is still Juliet's cousin since his mom was a Capulet. Or '''three''', if we count Mercutio...]] Dude, that's one messed-up family tree.

** ''Huge'' subversion in ''Anime/MobileFighterGGundam''. [[spoiler: We thought that main character Domon Kasshu was the Mad Scientists's Handsome Son... but he wasn't. Then we thought he was the Magnificent Bastard's Handsome Younger Brother... Guess what. He wasn't. His partner Rain Mikamura, on the other hand...]]

** Not to mention Nina. Sure, she is just five and anything but a love interest to the heroes, but she is cute, adorable, adores her State Alchemist Dad who shelters her [[spoiler: and maybe would have grown into a very cute young woman if her father hadn't used her for chimera experiments that ultimately doomed her]].

* Minato Sahashi is a male example, in ''Manga/{{Sekirei}}''. His mother is the head scientist of the Sekirei Plan, and leaves him innocent and oblivious to her work, as well as the identity of his father. [[spoiler: It is, of course, BigBad Minaka]]. Higa mistakenly believes the younger Sahashi sibling, Yukari, to be this as well. She's [[DaddysLittleVillain not]], and sets fire to his penthouse on her way out.

** Dr. Isaac Gilmore is child-less, and he subverts this by gaining the Cyborgs as his adoptive children ''after'' he stops being a MadScientist. [[spoiler: And there's the little detail that he was among the {{mad scientist}}s who ''created the cyborg team'' [[TheAtoner in the first place]].]]

* ''Anime/{{Boruto}}'': [[spoiler: It turns out that Mitsuki is the Mad Scientist Orochimaru's Handsome Son. Mitsuki says he respects his parent, but thankfully, doesn't seem to have inherited Oro's twisted personality and madness]].

** Talia Al-Ghul, the daughter of [[Characters/BatmanRasAlGhul Ra's Al-Ghul]]. Her loyalty to her father is... complicated. In the comics, it is usually unwavering. When she foils his [[spoiler: 'destroy the written word' scheme]], a lackey shoots her in the leg; the lackey is soon fed to the lions. In the video game, ''VideoGame/BatmanArkhamCity'', it's played darkly [[spoiler:[[InTheBack when he makes a move of threatening Batman with her life]] if he does not kill him]]. This results her in leaving him [[spoiler:after Batman saves her]].

* ''ComicBook/{{Vampirella}}'': Ha Ha Ha! See my shoehorning device! The daughter of the mad scientist who sent a giant mecha against Vampirella doesn't fall straightly, but still clearly recognizable under this trope as she is still a child. And crippled. [[spoiler: And the mech driver, mostly involuntarily. When Vampirella crashes the mech, opens it and learns she killed a child, you can practically see the steam blowing out of her ears.]]

** Interestingly, in an alternative ending, [[spoiler: Finklestein being on friendly terms with Jack is subverted with Finklestein [[TheManBehindTheCurtain being]] ''Oogie Boogie'', in order to teach Sally about [[GreenEyedMonster choosing Jack over him]], making the Finklestein/Sally relationship seem more carnal]]. This, along with canonically the next person the Doc creates to replace Sally seems to be a wife ([[ScrewYourself who looks exactly like him and even shares half his brain]]), has quite a few fans calling [[AlternativeCharacterInterpretation bullshit]] on the "beautiful daughter" explanation.

* Though Sloan from the ''Literature/InheritanceCycle'' is more JerkAss than BigBad ([[spoiler: though he does betray his village in Book 2]]), his daughter Katrina might count.%%How? Sloan isn't a mad scientist at all.

** Lackey's retelling of ''Theatre/SwanLake'', ''Literature/TheBlackSwan'', makes Odile into one of these. Her father expects her to betray him, which is painfully ironic since she is a textbook example of a [[WellDoneSonGuy Well Done Daughter Girl]] -- the HeelFaceTurn starts because she starts actually spending time with the swans, instead of just looking down on them. The supernatural control, i.e. him using her as "Odette" ''without her permission'', is just the last straw that makes her realize his true character. [[spoiler: And her turning on him is hardly subtle - ''she's'' the one to kill him, after all.]]

* Georgette Cuvelier in Harry Dickson's Adventures. The young woman turns out to be the daughter of [[spoiler: Pr Flax]], a former archenemy of the hero. Played straight in that she has a huge crush on Harry Dickson. Subverted in that [[spoiler: she remains evil and would rather avenge her father and die than surrender]].

* Played straight in ''Series/DenjiSentaiMegaranger'' in which Hinelar had a beautiful daughter named Shizuka. [[spoiler: Shibolena is based off of her and was created to look like her.]]

* And then there's Tora Ziyal from ''Series/StarTrekDeepSpaceNine'', the innocent daughter of Gul Dukat who always tried to give her father the benefit of the doubt. It didn't end well for her: [[spoiler: she dies a pretty pointless death at the hands of Dukat's [[TheDragon Dragon]] when even she was forced to accept that her father had run out of excuses for the way he behaved and the decisions he took. Always mentally unstable at best, her death was what snapped the last remaining thread of sanity Dukat had ever possessed]].
* ''Series/TheTwilightZone1959'': In the episode "[[Recap/TheTwilightZoneS2E44TheLatenessOfTheHour The Lateness of the Hour]]", Jana is the pretty daughter of inventor Dr. William Loren, who has created an entire menagerie of [[RobotMaid robot servants]] to assist him and his wife, so much so that Jana is worried her parents are becoming overly dependent on the robots. She yearns to see the world outside, but her father is overprotective and [[GildedCage won't let her leave the house]]. Of course, in a true ''Twilight Zone''-style twist, [[spoiler: Jana finds out that she is merely another robot creation of her father's, albeit the most humanistic one he has ever made]].

* ''VideoGame/{{Disgaea 2|Cursed Memories}}'' features Rozalin, the Evil Overlord Zenon's Beautiful but Spoiled Daughter who's contractually bound -- much to her annoyance -- to follow the [[IdiotHero ridiculously impulsive hero]] on his quest to kick her father's ass. While she starts out as outright murderous, things do start to change when she starts realizing that daddy doesn't seem to want her back safely so much as he wants her out of the way. Then again, [[spoiler: he's not actually her father. Or [[SamusIsAGirl the real Overlord Zenon]], for that matter..]].

** ''[[VideoGame/FireEmblemThracia776 Thracia 776]]'' has Sara, who is the adorable-looking granddaughter of [[spoiler: the mad priest Manfloy]].
** ''[[VideoGame/FireEmblemTheBlazingBlade Blazing Blade]]'' has ''both'' the Handsome Son (though "younger" than most, in a sense) and the Beautiful Daughter. [[spoiler: Ninian and Nils are the children of the BigBad of the game, the Dark Druid Nergal. ]]

** In ''VideoGame/FireEmblemAwakening'', [[spoiler: the ''PlayerCharacter'' is the runaway son/daughter of [[UglyGuysHotDaughter the very weird-looking]] [[TheDragon Dragon]], [[EvilSorcerer Validar]]. Even when using the older builds for the character (especially the 'older male' one), s/he is always said to be good-looking by the other characters]].

* ''Franchise/ResidentEvil'' gave us Sherry Birkin. In her first appearance in ''VideoGame/ResidentEvil2'', she's a middle schooler whose parents are both [[EvilutionaryBiologist scientists developing exotic bioweapons]] for [[EvilInc Umbrella Corp.]] Her father William decided to betray Umbrella out of greed and jealousy, feeling it would be better for he alone to profit from his life's work rather than his employer, starting a localized zombie apocalypse in the process and becoming a hideously mutated monster for his troubles. Sherry's mother isn't too far off in the moral spectrum, being dangerously amoral and coldhearted in pursuing her goals, though she at least recognizes the dangers of letting their work get out into the world unrestricted. Despite everything, Sherry survives the events of the game [[spoiler: albeit as host to a symbiotic monster]] and would make a return 15 years later in ''VideoGame/ResidentEvil6''.
* ''VideoGame/SonicFrontiers'': Sage is an ArtificialFamilyMember to Doctor Eggman. While Eggman is bald, fat, and has a frizzled moustache; Sage is a semi-CreepyChild who resembles a young girl. She's even referred to as "an adorable program" by Eggman himself, and while he's initially hesitant to treat her as more than a simple AI, in the end he accepts her as his daughter. [[spoiler: TheStinger of the GoldenEnding even has him rescue Sage in a backup program after the HeroicSacrifice she initially did to defeat [[BigBad The End]].]]

** Lune Zoldark, daughter of the original BigBad MadScientist Bian Zoldark, who eventually joins the good guys because she got a crush on one of the heroes, Masaki Andoh. Her defection from her father and falling in love are backwards, (she meets up with the good guys when she's coming back to fight her father, who she thinks has been corrupted by power, and [[spoiler: ''after'' they've already defeated him]]), but she's probably one of the best examples.

* In ''VideoGame/TraumaTeam'', we have [[spoiler: Rosalia Rossellini, Professor Sartre's adopted daughter]].

** BackStory-only: Lucrezia Mongfish, daughter of evil MadScientist Lucifer Mongfish, and a MadScientist herself. She denounces her father's evil and marries TheHero MadScientist Bill Heterodyne. Since Bill, his brother Barry, and all of their TrueCompanions are immortalized in the "[[FamedInStory Heterodyne stories]]," she is regarded as a [[TropeCodifier Codifier for this trope]] in universe[[note]](Especially the part where the audience likes her more before the obligatory HighHeelFaceTurn.)[[/note]]. [[spoiler:She turns out to be more evil than her father, and is in fact the BigBad]]. Her two sisters likely qualify for this as well.

** Zola, [[spoiler: Lucrezia's niece,]] is at least a mad scientist's beautiful granddaughter. Though unlike just about every other example in this work she doesn't show any sign of having inherited [[ScienceRelatedMemeticDisorder the Spark]], and it is unknown if her mother Demonica (Lucrezia's sister) had it.

** Colette, daughter of the Master of Paris, is so far the straightest yet iteration of this trope, being the beautiful daughter of a (take a shot) MadScientist, who helps out the heroes - but ''not'' in defiance of her father, because the Master of Paris is on the good guys' side, [[GoodIsNotNice just rather stern.]] [[spoiler: Colette ends up ascending to the role of Master of Paris upon her father's death, while [[TraumaticSuperpowerAwakening finally breaking through]] to become a Mad Scientist in her own right.]]

A MadScientist has only one child -- a [[TheIngenue beautiful but innocent girl]] in her late teens or early twenties, who loves her father dearly, and whom he has kept cloistered away from the world. Sometimes she has some small doubts about his goals or methods.

When the question of how a shriveled ugly man has a gorgeous daughter comes up, the response is either that she [[UglyGuyHotWife looks]] like [[StrongFamilyResemblance her mother]], or that the father [[IWasQuiteALooker did look as attractive as his daughter when he was younger]].

Often overlaps with TheUglyGuysHotDaughter. May overlap with DaddysLittleVillain. Might also end up being a PerkyFemaleMinion or DarkActionGirl, if she frequently helps her father in his work. Sister trope to ScienceHerosBabeAssistant, where she's a love interest to the scientist rather than his daughter.

* In ''Literature/TheReefsOfSpace'', Donna Creery is the daughter of the Planner of Earth, chief executive of the [[MasterComputer computer-controlled]] dictatorship which rules Earth, but she's sympathetic to Steve Ryeland, the scientist who's been arrested for reasons he doesn't understand. She eventually helps him escape when he ends up facing a death sentence.

** Dr. Finklestein and his beautiful artificial creation Sally. He's [[OverprotectiveDad smotheringly overprotective]], to the point that she has to poison him repeatedly to get a simple night out. Also, Finklestein is actually on friendly terms with Skellington -- really, the person he antagonizes most is Sally.

** [[spoiler:The leader of the Equalists, Amon/Noatak, is the TallDarkAndHandsome son of would-be mad dictator Yakone. The same goes for his younger brother, Tarrlok.]]

* Ennis of ''LightNovel/{{Baccano}}'', creation and "daughter" of the 1930 arc's BigBad, Szilard. She does twist it slightly in that [[spoiler: she betrays him not for TheHero, Firo (who, at that point, she thought was dead), but for the [[PluckyComicRelief comic]] OutlawCouple, Isaac and Miria]]. There's also the daughter of MadScientist and unapologetic ManipulativeBastard Huey Laforet, Chane Laforet, who falls in love with the AntiHero and professional assassin, Claire Stanfield. This ends up being subverted in that [[spoiler:Chane doesn't betray her father for him - instead, Huey just hires Claire]].

* ''LightNovel/{{Durarara}}'' has Shinra as the Mad Doctor's Handsome Son. He's... slightly more normal than his father Shingen, but he didn't get away without a screw or two loose.

* ''Manga/{{Cyborg 009}}'':

** Such as Rayna, Flint's "ward" from "Requiem for Methuselah". He was neither evil nor mad, he just didn't want his privacy to be disturbed (and for good reason).
** Inverted in "Conscience of the King", where it is the daughter who is the mad one, trying to protect her accused father (he wasn't squeaky clean either though).

* In ''Series/{{The Twilight Zone|1959}}'' season two episode "[[Recap/TheTwilightZoneS2E44TheLatenessOfTheHour The Lateness of the Hour]]", Jana is the pretty daughter of inventor Dr. William Loren, who has created an entire menagerie of [[RobotMaid robot servants]] to assist him and his wife, so much so that Jana is worried her parents are becoming overly-dependent on the robots. She yearns to see the world outside, but her father is overprotective and [[GildedCage won't let her leave the house]]. Of course, in a true ''Twilight Zone''-style twist, [[spoiler: Jana finds out that she is merely another robot creation of her father's, albeit the most humanistic one he has ever made]].

* Inverted on ''WesternAnimation/Gargoyles'': Halcyon Renard, while cynical and not without his flaws, is a strongly principled scientist. His daughter, Fox, is an amoral mercenary who even marries his equally amoral business rival.