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* ''Series/{{CSINY}}'' featured some genetically engineered goats which produced spider silk (see RealLife below, if that sounds crazy).

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* ''Series/{{CSINY}}'' featured some genetically engineered goats which produced spider silk (see RealLife below, if that sounds crazy). The same episode had a rat with a human ear growing on its back. The guy in the lab where both are created explained the process to the detectives.

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[[folder:Theater]]
* This seems to be the cornerstone of Norman Osborn's research in ''Theatre/SpiderManTurnOffTheDark'', and is the basis for the Crowd Song "DIY World," which is all about mutating your DNA to shapeshift and take on animal traits to survive catastrophes. Osborn later uses the same research to create supervillains, which is particularly weird when it comes to Swiss Miss. Do knives have DNA in this world?
[[/folder]]

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* Linkara of ''WebVideo/AtopTheFourthWall'' points out that Franchise/{{Superman}} does not have "superpowers"; his abilities are perfectly natural for a Kryptonian and no more "super" than any normal human ability. To remove his powers in JLA: Act of God, he would have to be completely altered genetically, more likely killing him than removing his powers. Linkara even says genetics are not Lego bricks.


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* ''WebOriginal/{{Mortasheen}}'' is what happens when you get an entire setting built around this trope.

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* In ''Literature/VWars'', a newly-discovered ancient virus, thought to be a variation of the flu, in the melting polar ice caps starts infecting people. At first the symptoms are flu-like, but then some people start turning into various kinds of vampires, werewolves, and other shifters. A scientist theorizes that the virus is activating "junk" DNA in some people, turning them into new species, with each ethnic group typically having its own myth about these creatures, possibly left over from a previous outbreak of the virus. Very few of these kinds are able to pass on their particular mutation to others. Of those that can, a particular example are the vurdalak, Russian vampires. They can only feed on those they love (or are at least mildly attracted to), but anyone killed during a feeding comes back as a vurdalak. [[spoiler:One of them eventually starts killing the others by blowing their brains out, leaving the last bullet for herself.]]

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* In Les Bohem's ''Literature/{{Junk}}'', a piece of junk DNA left over from aliens interbreeding with humans thousands of years ago is starting to activate, turning people into murder machines with superhuman abilities.


* ''WebOriginal/OrionsArm'', for all its much vaunted scientific accuracy, still features this trope in the form of splices (animals augmented with human DNA) and rianths (humans who added animal genes to themselves).

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* ''WebOriginal/OrionsArm'', for all its much vaunted scientific accuracy, still ''WebOriginal/OrionsArm'' features this trope in the form of splices [[https://www.orionsarm.com/eg-topic/45beac611ad40 splices]] (animals augmented with human DNA) and rianths [[https://www.orionsarm.com/eg-topic/45beaa73c347e rianths]] (humans who added animal genes to themselves).themselves). Though as explained on the rianth page, the process is more complicated than just adding in animal genes: it can involve surgery, cybernetics and/or genetic modification.


* In ''[[Creator/DetsniyOffSkiword Kid Icarus Uprising 2: Hades Revenge]]'', we see Pandora mention that she injected seahorse “[[RougeAnglesOfSatin jeans]]” into [[VideoGame/FinalFantasyVII Cloud “Strafe”]], which is used to [[MrSeahorse make him pregnant]].

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* In ''[[Creator/DetsniyOffSkiword Kid Icarus Uprising 2: Hades Revenge]]'', we see Pandora mention that she injected seahorse “[[RougeAnglesOfSatin jeans]]” into [[VideoGame/FinalFantasyVII Cloud “Strafe”]], which is used to [[MrSeahorse [[MisterSeahorse make him pregnant]].

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* Progressing far enough in ''VideoGame/EvolveIdle'' will allow the player to use plasmids to purchase genetic upgrades (such as a bonus to resource storage capacity) that carry over to every new species created. Eventually one can use plasmids add or subtract genetic traits for the various races and even craft unique races from various existing traits.


* ''Literature/KillerSpecies'': This is series villain Dr. Catalyst's M.O., as he combines DNA from different species to create a new type of creature specifically bred to hunt down and destroy an invasive species that's devastating a particular environment. Book 1 features Pterogators (a combination alligator/great gray owl created to destroy the anacondas and boa constrictors in the Everglades), book 2 the Muraecudas (a hybrid of Moray eel, reef shark and barracuda made for hunting lionfish), book 3 the Blood Jackets (a hybrid of baldface hornet and vampire bat, which target humans), and book 4 a combination hyena/Florida panther (a lone specimen made to hunt and kill Emmet Doyle, who's thwarted his plans multiple times).

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* ''Literature/KillerSpecies'': This is series villain Dr. Catalyst's M.O., as he combines DNA from different species to create a new type of creature specifically bred to hunt down and destroy an invasive species that's devastating a particular environment. Book 1 features Pterogators (a combination alligator/great gray owl created to destroy the anacondas and boa constrictors in the Everglades), book 2 introduces the Muraecudas (a hybrid of Moray eel, reef shark and barracuda made for hunting lionfish), book 3 debuts the Blood Jackets (a hybrid of baldface hornet and vampire bat, which target humans), and book 4 a combination hyena/Florida panther centers around the Swamp Cat (a lone hybrid specimen combining the DNA of a hyena and Florida panther, made to hunt and kill Emmet Doyle, who's thwarted his Doyle for thwarting Catalyst's plans multiple times). times).

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* The main villain of ''Series/ChoushinseiFlashman'', Ra Deus and his underling Dr. Kefler have this as their main obsession. They use DNA to create the MonsterOfTheWeek and Deus himself is questing to become the supreme lifeform in the universe by acquiring more genetic material. [[spoiler:As it turns out, Deus is in fact a ''living mass of genetics''. After this gets exposed, Kefler turns against him, and turns Deus into a monster.]]


* In ''[[Creator/DetsniyOffSkiword Kid Icarus Uprising 2: Hades Revenge]]
[[/folder]]'', we see Pandora mention that she injected seahorse “[[RougeAnglesOfSatin jeans]]” into [[VideoGame/FinalFantasyVII Cloud “Strafe”]], which is used to [[MrSeahorse make him pregnant]].

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* In ''[[Creator/DetsniyOffSkiword Kid Icarus Uprising 2: Hades Revenge]]
[[/folder]]'',
Revenge]]'', we see Pandora mention that she injected seahorse “[[RougeAnglesOfSatin jeans]]” into [[VideoGame/FinalFantasyVII Cloud “Strafe”]], which is used to [[MrSeahorse make him pregnant]].
[[/folder]]


[[/folder]]

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[[/folder]]
* In ''[[Creator/DetsniyOffSkiword Kid Icarus Uprising 2: Hades Revenge]]
[[/folder]]'', we see Pandora mention that she injected seahorse “[[RougeAnglesOfSatin jeans]]” into [[VideoGame/FinalFantasyVII Cloud “Strafe”]], which is used to [[MrSeahorse make him pregnant]].


** In the episode "Lineage", B'Elanna, half-human[=/=]half-klingon with issues, is upset to discover that the baby she is pregnant with by her human husband Tom has some klingon facial features, since those traits are dominant and can take generations to breed out. She attempts to forcibly reprogram the Doctor to genetically remove the klingon features in utero while performing resequencing to fix a spinal issue. Tom and the rest of her friends are appalled.

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** In the episode "Lineage", B'Elanna, half-human[=/=]half-klingon half-Human[=/=]half-Klingon with issues, is upset to discover that the baby she is pregnant with by her human husband Tom has some klingon Klingon facial features, since those traits are dominant and can take generations to breed out. She attempts to forcibly reprogram the Doctor to genetically remove the klingon Klingon features in utero while performing resequencing to fix a spinal issue. Tom and the rest of her friends are appalled.

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