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* Often happens with methanol. This substance looks like ethanol, smells like ethanol, tastes like ethanol and even produces buzz like ethanol. But if you're lucky, it'll burn your eyes from inside for good, and if you're unlucky, it'll kill you.

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* Often happens with methanol. This substance looks like ethanol, smells like ethanol, tastes like ethanol and even produces a buzz like ethanol. But if you're lucky, it'll burn your eyes from inside for good, and if you're unlucky, it'll kill you.

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* The ''Savage Avengers'' had Mulan Gath plotting to gradually devour Shuma-Gorath and steal its power by spiking drug supplies with something that causes whoever takes them to be possessed by a piece of it.
* ''Miles Morales: Spider-Man'' had Miles' adult 616 counterpart plot a takeover of the underworld by spiking drugs with Ultimate Goblin serum, converting masses into an army under Ultimate Osborn's control.
* One arc in Secret Avengers involved the ground bones of prehistoric eldritch monsters being mixed in with drug supplies in Russia. These creatures existed before the afterlives did and had ManySpiritsInsideOfOne, meaning the spirits are trapped inside their remains. They are released when the bones are burned, possessing and empowering whoever smokes them.


Poor Bob, he just ''had'' to JackUpWithPhlebotinum. Instead of the good stuff, the stuff he consumed was actually some sort of harmful substance or AppliedPhlebotinum, and he has now become either a casualty of some bizarre effect or something less than human. Either way, Bob himself has now become an integral part of the plot somehow. Perhaps his demise sets events in motion that drive the plot, or perhaps he becomes some sort of monster and is now the antagonist. Bottom line is he ''really'' shouldn't have done the stuff.

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Poor Bob, he just ''had'' to JackUpWithPhlebotinum. Instead Bob: instead of the good stuff, the stuff he consumed was actually some sort of harmful substance or AppliedPhlebotinum, and he has now become either a casualty of some bizarre effect or [[WasOnceAMan something less than human.human]]. Either way, Bob himself has now become an integral part of the plot somehow. Perhaps his demise sets events in motion that drive the plot, or perhaps he becomes some sort of monster and is now the antagonist. Bottom line is he ''really'' shouldn't have done the stuff.

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* ''Franchise/MassEffect'' has a FantasticDrug where cocaine is exposed to Element Zero. The end result has not only the mind-altering effects of cocaine, but gives the user low-level biotic (telekenetic) abilities. Needless to say, someone who is coked up, able to TK small objects around the room, and hasn't the training to do it properly is a headache for the security forces.


* A Comicbook/{{Spider-Man}} story had the Absorbing Man transforming himself into cocaine, then being cut up and sold to unsuspecting addicts who got their own superpowers.

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* A Comicbook/{{Spider-Man}} Comicbook/SpiderMan story had the Absorbing Man transforming himself into cocaine, then being cut up and sold to unsuspecting addicts who got their own superpowers.


* In ''Film/PulpFiction'', Mia Wallace finds what she thinks is cocaine is Vincent Vega's coat jacket, and snorts it up. It's in fact ''VERY'' pure "madman" heroin that Vincent bought earlier, and she [=ODs=] on the spot, only escaping death through Vincent's quick thinking and a well-timed adrenaline shot to the heart.

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* In ''Film/PulpFiction'', Mia Wallace finds what she thinks is cocaine is Vincent Vega's coat jacket, and snorts it up. It's in fact ''VERY'' pure "madman" heroin that Vincent bought earlier, and she [=ODs=] on the spot, only escaping death through Vincent's quick thinking and a well-timed adrenaline shot to the heart.


* In ''Film/PulpFiction'', Mia Wallace finds what she thinks is cocaine is Vincent Vega's coat jacket, and snorts it up. It's in fact ''VERY'' pure heroin, and she [=ODs=] on the spot.

to:

* In ''Film/PulpFiction'', Mia Wallace finds what she thinks is cocaine is Vincent Vega's coat jacket, and snorts it up. It's in fact ''VERY'' pure heroin, "madman" heroin that Vincent bought earlier, and she [=ODs=] on the spot.spot, only escaping death through Vincent's quick thinking and a well-timed adrenaline shot to the heart.


[[folder:VideoGames]]
* Much of the action in ''VideoGame/ShadowWarrior2'' revolves around Shade, a drug distilled from Crude which comes from the Shadow Realm. Humans who use it for too long or who use too much of it end up turning into demons.
[[/folder]]



** [[VodkaDrunkenski Russians]] have devised a folk way to tell methanol from ethanol. You make a small spiral out of copper wire, heat it with a cigarette lighter and drench in the suspicious alcohol. If you smell "morgue" (formaldehyde gas, a very characteristic "stinging" smell), this is deadly stuff.

to:

** [[VodkaDrunkenski Russians]] have devised a folk way to tell methanol from ethanol. You make a small spiral out of copper wire, heat it with a cigarette lighter and drench in the suspicious alcohol. If you smell "morgue" (formaldehyde gas, a very characteristic "stinging" smell), this is it's the deadly stuff.


* A {{Spider-Man}} story had the Absorbing Man transforming himself into cocaine, then being cut up and sold to unsuspecting addicts who got their own superpowers.
* {{Wolverine}} once fought an EldritchAbomination called Sporr, which had been blasted to molecules millennia before by [[BenevolentPrecursors the Celestials]]; it reemerged when someone deliberately overdosed on cocaine that was grown on the mountain where it "died" because said cocaine gave its users limited super-powers.

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* A {{Spider-Man}} Comicbook/{{Spider-Man}} story had the Absorbing Man transforming himself into cocaine, then being cut up and sold to unsuspecting addicts who got their own superpowers.
* {{Wolverine}} Comicbook/{{Wolverine}} once fought an EldritchAbomination called Sporr, which had been blasted to molecules millennia before by [[BenevolentPrecursors the Celestials]]; it reemerged when someone deliberately overdosed on cocaine that was grown on the mountain where it "died" because said cocaine gave its users limited super-powers.



* The SuicideSquad once thwarted a scheme by voodoo-using New Orleans gangsters to distribute free heroin samples to addicts that would turn them into a [[ZombieApocalypse literal zombie army]].

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* The SuicideSquad Comicbook/SuicideSquad once thwarted a scheme by voodoo-using New Orleans gangsters to distribute free heroin samples to addicts that would turn them into a [[ZombieApocalypse literal zombie army]].


* One of the origins of the Sentry of MarvelComics (He has a MultipleChoicePast) is that he was a junkie who stole the SuperSerum in hopes it would get him high. It turned out remarkably well for him...except for the side effects.

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* One of the origins of the Sentry of MarvelComics Creator/MarvelComics (He has a MultipleChoicePast) is that he was a junkie who stole the SuperSerum in hopes it would get him high. It turned out remarkably well for him...except for the side effects.


* ''Film/ReturnOfTheLivingDead 5: Rave from the Grave'' has kids in raves gulping down pills of what they think is a rave drug like Ecstasy, but it is actually Trioxin, the chemical phlebotinum from the movies that turns people into zombies.

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* ''Film/ReturnOfTheLivingDead 5: Rave from the Grave'' ''Film/ReturnOfTheLivingDeadRaveToTheGrave'' has kids in raves gulping down pills of what they think is a rave drug like Ecstasy, but it is actually Trioxin, the chemical phlebotinum from the movies that turns people into zombies.


* On ''TheTick'', Dinosaur Neil, a paleontologist in a dinosaur costume, accidentally eats dinosaur genetic material thinking it was pasta salad, which turns him into a real dinosaur.

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* On ''TheTick'', ''WesternAnimation/TheTick'', Dinosaur Neil, a paleontologist in a dinosaur costume, accidentally eats dinosaur genetic material thinking it was pasta salad, which turns him into a real dinosaur.


** [[VodkaDrunkenski Russians]] have devised a folk way to tell methanol from ethanol. You make a small spiral out of copper wire, heat it with a cigarette lighter and drench in the suspicious alcohol. If you smell "morgue" (formaldehyde gas), this is deadly stuff.

to:

** [[VodkaDrunkenski Russians]] have devised a folk way to tell methanol from ethanol. You make a small spiral out of copper wire, heat it with a cigarette lighter and drench in the suspicious alcohol. If you smell "morgue" (formaldehyde gas), gas, a very characteristic "stinging" smell), this is deadly stuff.


* Like TheSentry, but far less powerful, minor Spider-Man villain Freak started as a drug addict who consumed a mutagen thinking it was a new designer narcotic.

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* Like TheSentry, ComicBook/TheSentry, but far less powerful, minor Spider-Man villain Freak started as a drug addict who consumed a mutagen thinking it was a new designer narcotic.



* In Creator/GrantMorrison's ComicBook/{{X-Men}} run, a new power-enhancing stimulant called "Kick" starts taking the mutant community by storm. Turns out it's [[spoiler: a mind-controlling, aerosol form of the malevolent, sentient bacteria Sublime, the ultimate villain of the story.]]

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* In Creator/GrantMorrison's ComicBook/{{X-Men}} ComicBook/XMen run, a new power-enhancing stimulant called "Kick" starts taking the mutant community by storm. Turns out it's [[spoiler: a mind-controlling, aerosol form of the malevolent, sentient bacteria Sublime, the ultimate villain of the story.]]


* On Series/StargateAtlantis, Ford is injected with the enzyme Wraith use to strengthen humans so they can survive the feeding process, but doesn't get eaten afterwards. As a result, he gains super speed, strength, and stamina. The enzyme proves highly addictive, severely impairs judgment, and the withdrawal process is not pleasant. Ford ends up going rogue and gathering together a band of guys who use the enzyme to aid them in their fight against the Wraith.

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* On Series/StargateAtlantis, ''Series/StargateAtlantis'', Ford is injected with the enzyme Wraith use to strengthen humans so they can survive the feeding process, but doesn't get eaten afterwards. As a result, he gains super speed, strength, and stamina. The enzyme proves highly addictive, severely impairs judgment, and the withdrawal process is not pleasant. Ford ends up going rogue and gathering together a band of guys who use the enzyme to aid them in their fight against the Wraith.Wraith.
* In the ''Series/{{Millennium}}'' episode "Human Essence" Emma Hollis's [[FoolishSiblingResponsibleSibling junkie sister]] claims that a new strain of heroin is turning users into monsters. Frank and Emma gradually come to realize that she's right.

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