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[[folder:Newspaper Comics]]
* One comic from ''ComicStrip/TheFarSide'' depicts a brain transplant between a human and a duck. The duck, who can now speak English, goes on to become the leader of a great flock; the human, who now only quacks, just wanders south.
[[/folder]]


* Bioethicists have near-universally rejected the prospect of brain transplantation, although for a different reason than this trope generally addresses: mathematically, a brain-dead donor body can save ''far'' more lives if its individual organs are harvested for transplantation, rather than squandering them on preserving just one person.

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* Bioethicists have near-universally rejected the prospect of brain transplantation, although for a different reason than this trope generally addresses: mathematically, a brain-dead donor body can save ''far'' more lives people if its individual organs are harvested for transplantation, transplantation into several different recipients, rather than squandering them all on preserving just one person.''one'' life.

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* ''Franchise/WonderWoman'': While Golden Age Giganta was the result of a gorilla going through an DevolutionDevice her later iterations are the result of Dr. Zeul's mind being transferred, at least temporarily as an emergency measure, into one.


Often involves a BrainInAJar at some point.

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Often involves a BrainInAJar at some point.
point. Whole-body OrganTheft may also become a factor, if the donor body isn't yet deceased or brain-dead.

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* Bioethicists have near-universally rejected the prospect of brain transplantation, although for a different reason than this trope generally addresses: mathematically, a brain-dead donor body can save ''far'' more lives if its individual organs are harvested for transplantation, rather than squandering them on preserving just one person.


* Creator/IsaacAsimov's "{{Literature/Sally}}": Gellhorn's GetRichQuickScheme involves taking the [[{{Unobtainium}} positronic brains]] from "retired" AutomatedAutomobiles and putting them into brand-new bodies, forcing them back to work.



* In ''Fountain Society'', a dying scientist's brain is transplanted into a body of a younger man. He eventually rebels against the eponymous society, [[spoiler:and destroys their skyscraper by crashing a plane on it while the BigBad is going through the same operation]].
* In ''Literature/IWillFearNoEvil'' by Creator/RobertAHeinlein, the protagonist has their brain transplanted into a woman's body, it doesn't end well. The event is later mentioned in ''Literature/TimeEnoughForLove'' when the possibility of being transferred into an OppositeSexClone is suggested to Lazarus Long, he rejects it.
* In ''[[Literature/JohnCarterOfMars Mastermind of Mars]]'', the bulk of [[MadScientist Ras Thavas']] research involves swapping people's brains. He's even made a business out of it, transplanting the brains of the old and wealthy and/or powerful into younger bodies.
* In ''[[https://www.fictionpress.com/s/3214035/1/SI S.I.]]'' the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a body nearby that lacked a central nervous system.
* This is possible, albeit risky, in ''Franchise/StarWarsLegends''. Monks of the B'Omarr order have their brains removed [[BrainInAJar and placed into life-support jars]] upon reaching enlightenment so they can continue to contemplate the universe forever. Less scrupulous B'Omarr initiates have been known to perform the operation on unwilling patients and even reverse it, implanting brains into other bodies. One of the short stories in ''Literature/TalesFromJabbasPalace'' implies that Bib Fortuna eventually manages to escape his AndIMustScream fate that way.
* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.

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* In ''Fountain Society'', ''Literature/FountainSociety'', a dying scientist's brain is transplanted into a body of a younger man. He eventually rebels against the eponymous society, [[spoiler:and destroys their skyscraper by crashing a plane on it while the BigBad is going through the same operation]].
* In ''Literature/IWillFearNoEvil'' by Creator/RobertAHeinlein, Creator/RobertAHeinlein's ''Literature/IWillFearNoEvil'', the protagonist has their brain transplanted into a woman's body, it doesn't end well. The event is later mentioned in ''Literature/TimeEnoughForLove'' when the possibility of being transferred into an OppositeSexClone is suggested to Lazarus Long, he rejects it.
* In ''[[Literature/JohnCarterOfMars Mastermind ''Literature/JohnCarterOfMars'''s ''Mastermind of Mars]]'', Mars'', the bulk of [[MadScientist Ras Thavas']] research involves swapping people's brains. He's even made a business out of it, transplanting the brains of the old and wealthy and/or powerful into younger bodies.
* In ''[[https://www.fictionpress.com/s/3214035/1/SI S.I.]]'' the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a body nearby that lacked a central nervous system.
* This is possible, albeit risky, in ''Franchise/StarWarsLegends''. Monks of the B'Omarr order have their brains removed [[BrainInAJar and placed into life-support jars]] upon reaching enlightenment so they can continue to contemplate the universe forever. Less scrupulous B'Omarr initiates have been known to perform the operation on unwilling patients and even reverse it, implanting brains into other bodies. One of the short stories in ''Literature/TalesFromJabbasPalace'' implies that Bib Fortuna eventually manages to escape his AndIMustScream fate that way.
* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.
bodies.


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* In ''{{Literature/SI}}'' ([[https://www.fictionpress.com/s/3214035/1/SI link]]), the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a body nearby that lacked a central nervous system.
* ''Franchise/StarWarsLegends'': Monks of the B'Omarr order have their brains removed [[BrainInAJar and placed into life-support jars]] upon reaching enlightenment so they can continue to contemplate the universe forever. Less scrupulous B'Omarr initiates have been known to perform the operation on unwilling patients and even reverse it, implanting brains into other bodies. One of the short stories in ''Literature/TalesFromJabbasPalace'' implies that Bib Fortuna eventually manages to escape his AndIMustScream fate that way.
* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.

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* ''Film/MonsterMash1995'' has Dr. Frankenstein scheme to put Scott's brain into the body of his monster.

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* ''Film/ABCsOfDeath2'': "Q [[spoiler:is for Questionnaire]]" ends with the man's brain being put into the body of a gorilla.


* The French comic ''Une Femme Dans la peau'' or ''Johanna'' uses this as a plot point, but plays more as a GenderBender story. Long story short, a middle-aged, lecherous, businessman ends up hit by a bus the same day a beautiful blond twenty-something ODs. Both corpses are acquired by an elderly Nazi scientist and used as the first test of an experimental brain-swapping procedure. It works... but the scientist gets [[ShockAndAwe fried]] for his trouble. Now, the businessman has to deal with being a blonde bombshell, starting his/her life over, and having to dodge the scientist's elderly Nazi-Remnant chums and stop them from using the procedure in a two-for-one FountainOfYouth/WorldDomination plot.

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* The French comic ''Une Femme Dans la peau'' or ''Johanna'' uses this as a plot point, but plays more as a GenderBender story. Long story short, a middle-aged, lecherous, businessman ends up hit by a bus the same day a beautiful blond twenty-something ODs. Both corpses are acquired by an elderly Nazi scientist and used as the first test of an experimental brain-swapping procedure. It works... but the scientist gets [[ShockAndAwe fried]] for his trouble. Now, the businessman has to deal with being a blonde bombshell, starting his/her life over, and having to dodge the scientist's elderly Nazi-Remnant chums and stop them from using the procedure in a two-for-one FountainOfYouth/WorldDomination FountainOfYouth/[[TakeOverTheWorld World Domination]] plot.


* The French comic ''Une Femme Dans la peau'' or ''Johanna'' uses this as a plot point, but plays more as a GenderBender story. Long story short, a middle-aged, lecherous, businessman ends up hit by a bus the same day a beautiful blond twenty-something ODs. Both corpses are acquired by an elderly Nazi scientist and used as the first test of an experimental brain-swapping procedure. It works... but the scientist gets [[ShockAndAwe fried]] for his trouble. Now, the businessman has to deal with being a blonde bombshell, starting his/her life over, and having to dodge the scientist's elderly Nazi-Remnant chums and stop them from using the procedure in a two-for-one FountainOfYouth/WorldDomination plot.



* At the end of ''Film/TheManWithTwoBrains'', Dr Hfuhruhurr, inventor of "cranial screw-top brain surgery", transplants the BrainInAJar he's been dating into the body of his evil wife.

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* At the end of ''Film/TheManWithTwoBrains'', Dr Dr. Hfuhruhurr, inventor of "cranial screw-top brain surgery", transplants the BrainInAJar he's been dating into the body of his evil wife.



* In ''Film/TheGhostOfFrankenstein'' Ygor makes Dr. Frankenstein transplant his (Ygor's) brain into the monster's body so they'll be "together forever." Unfortunately they don't have the same blood type so Ygor!Monster is blind, leading to the eyes closed/arms outstretched shuffle that the Monster is Flanderized into having.

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* In ''Film/TheGhostOfFrankenstein'' Ygor makes Dr. Frankenstein transplant his (Ygor's) brain into the monster's body so they'll be "together forever." Unfortunately Unfortunately, they don't have the same blood type so Ygor!Monster is blind, leading to the eyes closed/arms outstretched shuffle that the Monster is Flanderized into having.

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* In ''Film/JesseJamesMeetsFrankensteinsDaughter'', Maria Frankenstein transplants her grandfather's artificial brain into Hank's body.


* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.



* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.


* In Creator/HPLovecraft's "Literature/TheWhispererInDarkness" the Mi-Go have a tendency to put [[BrainInAJar brains in jars]] and at least claim they can easily put them back in bodies, not necessarily their original ones.
* In ''Literature/IWillFearNoEvil'' by Creator/RobertAHeinlein the protagonist has their brain transplanted into a woman's body, it doesn't end well. The event is later mentioned in ''Literature/TimeEnoughForLove'' when the possibility of being transferred into an OppositeSexClone is suggested to Lazarus Long, he rejects it.
* In [[https://www.fictionpress.com/s/3214035/1/SI S.I.]] the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a body nearby that lacked a central nervous system.

to:

* In Creator/HPLovecraft's "Literature/TheWhispererInDarkness" the Mi-Go have a tendency to put [[BrainInAJar brains in jars]] and at least claim they can easily put them back in bodies, not necessarily their original ones.
* In ''Literature/IWillFearNoEvil'' by Creator/RobertAHeinlein the
The ''Literature/{{Airhead}}'' trilogy kicks off when protagonist has their Emerson, after suffering fatal wounds when a TV falls on her at the grand opening of a department store, wakes up with her brain having been secretly transplanted into a woman's body, it doesn't end well. The event is later mentioned in ''Literature/TimeEnoughForLove'' when the possibility of being transferred into an OppositeSexClone is suggested to Lazarus Long, he rejects it.
* In [[https://www.fictionpress.com/s/3214035/1/SI S.I.]] the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a
body nearby of a teen supermodel who had a contract with the large corporation that lacked owns the store, and by coincidence was felled by an undetected congenital brain defect at the same time as Emerson was struck by the TV. Em not only discovers that the corporation has been running a central nervous system.secret transplantation program for the ultra-rich, but she's forced to pose as the supermodel as if nothing has changed (including FakingAmnesia) or else.



* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's brain is thrown away.

to:

* ''Literature/EmpireFromTheAshes'': In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based first book, BigBad Anu and the various awake members of his faction of mutineers have been using this method to stay immortal. Lower-ranking mutineers have to use the bodies of ordinary Earth-born humans, but Anu and his inner circle only take Imperial bodies, from the thousands of mutineers still in stasis. [[spoiler:During the raid on brain transplants into younger clones. The clone's Anu's enclave, after the death of his second-in-command Inanna, Geb, a member of the northern faction, is horrified to realize that the last body Inanna had taken was that of the wife of Horus, the leader of the northerners, who thought she'd been killed during the mutiny on ''Dahak''. Geb vapourizes the body and asks Colin to put a lock on images of Inanna for the century she'd been inhabiting Tanisis' body to spare Horus the heartbreak.]]
* In ''Fountain Society'', a dying scientist's
brain is thrown away.transplanted into a body of a younger man. He eventually rebels against the eponymous society, [[spoiler:and destroys their skyscraper by crashing a plane on it while the BigBad is going through the same operation]].
* In ''Literature/IWillFearNoEvil'' by Creator/RobertAHeinlein, the protagonist has their brain transplanted into a woman's body, it doesn't end well. The event is later mentioned in ''Literature/TimeEnoughForLove'' when the possibility of being transferred into an OppositeSexClone is suggested to Lazarus Long, he rejects it.



* This is possible, albeit risky, in the ''Franchise/StarWarsExpandedUniverse''. Monks of the B'Omarr order have their brains removed [[BrainInAJar and placed into life-support jars]] upon reaching enlightenment so they can continue to contemplate the universe forever. Less scrupulous B'Omarr initiates have been known to perform the operation on unwilling patients and even reverse it, implanting brains into other bodies. One of the short stories in ''Literature/TalesFromJabbasPalace'' implies that Bib Fortuna eventually manages to escape his AndIMustScream fate that way.
* In ''Fountain Society'', a dying scientist's brain is transplanted into a body of a younger man. He eventually rebels against the eponymous society, [[spoiler:and destroys their skyscraper by crashing a plane on it while the BigBad is going through the same operation]].

to:

* In ''[[https://www.fictionpress.com/s/3214035/1/SI S.I.]]'' the protagonist is awakened from cryonic suspension, and suffers severe ethylene glycol poisoning. Fortunately there happened to be a body nearby that lacked a central nervous system.
* This is possible, albeit risky, in the ''Franchise/StarWarsExpandedUniverse''.''Franchise/StarWarsLegends''. Monks of the B'Omarr order have their brains removed [[BrainInAJar and placed into life-support jars]] upon reaching enlightenment so they can continue to contemplate the universe forever. Less scrupulous B'Omarr initiates have been known to perform the operation on unwilling patients and even reverse it, implanting brains into other bodies. One of the short stories in ''Literature/TalesFromJabbasPalace'' implies that Bib Fortuna eventually manages to escape his AndIMustScream fate that way.
* In ''Fountain Society'', Creator/HPLovecraft's "Literature/TheWhispererInDarkness" the Mi-Go have a dying scientist's tendency to put [[BrainInAJar brains in jars]] and at least claim they can easily put them back in bodies, not necessarily their original ones.
* In the ''Literature/VorkosiganSaga'', Jackson's Whole infamously hosts life extension clinics based on brain transplants into younger clones. The clone's
brain is transplanted into a body of a younger man. He eventually rebels against the eponymous society, [[spoiler:and destroys their skyscraper by crashing a plane on it while the BigBad is going through the same operation]].thrown away.



* ''Series/DoctorWho'':
** In [[Recap/DoctorWhoS13E5TheBrainOfMorbius "The Brain of Morbius"]], BrainInAJar Morbius intends to have himself transplanted into the Doctor's head.
** In [[Recap/DoctorWho2016CSTheReturnOfDoctorMysterio "The Return of Doctor Mysterio"]], the aliens have their brains transplanted into human hosts by a team of scary surgeons.



* In ''Series/KamenRiderGaim'', Ryoma Sengoku at one point transplants his brain into [[Film/KikaiderReboot Hakaider]]'s robot body, fights against Gaim and Kikaider, and then transplants his brain back to his own body with no apparent lasting effects.



* ''Series/OutOfJimmysHead'' has this happen to the eponymous character, using the brain of a MrAltDisney. However, the retention of the [[ArtisticLicenseBiology "personality gland"]] lets Jimmy keep everything that's himself.



* ''Series/OutOfJimmysHead'' has this happen to the eponymous character, using the brain of a MrAltDisney. However, the retention of the [[ArtisticLicenseBiology "personality gland"]] lets Jimmy keep everything that's himself.



* In ''Series/KamenRiderGaim'', Ryoma Sengoku at one point transplants his brain into [[Film/KikaiderReboot Hakaider]]'s robot body, fights against Gaim and Kikaider, and then transplants his brain back to his own body with no apparent lasting effects.
* ''Series/DoctorWho'':
** In "The Brain of Morbius", BrainInAJar Morbius intends to have himself transplanted into the Doctor's head.
** In "The Return of Doctor Mysterio", the aliens have their brains transplanted into human hosts by a team of scary surgeons.



* In the ''WesternAnimation/DextersLaboratory'' episode "Dexter's Assistant," Dexter puts a new brain in Dee Dee's head so she'll be smart enough to help him with his science experiment. Bizarrely, this makes her smarter without changing her memories or identity, and it's never explained where the brain came from.

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* In the ''WesternAnimation/DextersLaboratory'' episode "Dexter's Assistant," Assistant", Dexter puts a new brain in Dee Dee's head so she'll be smart enough to help him with his science experiment. Bizarrely, this makes her smarter without changing her memories or identity, and it's never explained where the brain came from.

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* In ''Film/LadyFrankenstein'', Tanya uses her father's techniques to transplant the brain of her aging lover Charles into the body of the physically perfect but mentally defective stable hand Thomas.


* ''Series/DoctorWho'': In "The Return of Doctor Mysterio", the aliens have their brains transplanted into human hosts by a team of scary surgeons.

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* ''Series/DoctorWho'': ''Series/DoctorWho'':
** In "The Brain of Morbius", BrainInAJar Morbius intends to have himself transplanted into the Doctor's head.
**
In "The Return of Doctor Mysterio", the aliens have their brains transplanted into human hosts by a team of scary surgeons.

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