I wrote a review for this series, but it's gone now. I'll be more brief.
Like many melodramas, House
got caught in the trap of trying to top itself. House hits rock bottom, his friends abandon him, he cleans himself up, is bounced off back to work — this has been fodder for four seasons already.
At the same time we're covering old ground, the most enjoyable parts of the show are stripped away. Most of the cast (Wilson, Foreman, Chase) are adrift, locked in old patterns; or else attending to mundane aspects of domestic life, like Taub and Foreman moving in together, or Taub cheating on women (despite looking like a garden gnome.) It's not very stimulating stuff. Another weird thing is how the patients (the cornerstone of the show's premise, or at least they used to be) aren't that prominent anymore. This in turn harms Dr. House as a character, since his gifts and bulldog perseverance are wasted, and we end up with a mean boss who glowers all the time, bullies his coworkers, and is an even worse friend than Tom Green.