As for the House edit, I put it here.

I thought it was interesting to see how House's and Wilson's contrasting personalities were symbolized by their use of contrasting pronouns ("jerk-ish though guy" ore vs "nice polite guy" boku). If it simply was about House using ore or Wilson using boku, I probably wouldn't have added it- it's the contrast that made me think it as worthy of being added.

It indeed is from the Japanese dub of the show- I didn't specify it because I thought people would have figured it out, but I guess it wasn't clear enough. Sorry to everyone for the confusion.

Whoops, realized I mixed up the characters. False alarm! :D;;

Anime Japanese tends to be very stylized, not just the vocabulary but also the tone, rhythm of speech, etc. Anime almost always uses standard Japanese, and if someone speaks a dialect, it's usually very exaggerated (Lovely Complex is a rare exception). Anime characters also speak more slowly and clearly than people do IRL (just compare a seiyuu's speech when he's playing a character and when he's being interviewed), and often have unrealistic speech patterns. The vocab often mixes modern and archaic speech (and whent they use archaic speech it's sometimes on a Ye Olde Butcherede Englishe level) and anime characters use words that nobody ever uses IRL. For example if you use "kisama" or "temee" in modern Japan people will a) laugh, b) think you're crazy, c) think you're an otaku who learned Japanese from anime. Characters like Vegeta or Ichigo can get away with very rude speech because it's just not realistic, nobody talks like that IRL.

Depends. If she's a type 2 Ojou she could use "watakushi" along with refined speech to give an impression of being above other people.

If she's not, she'll probably stick to "watashi" or "atashi" (depending on her normal usage), conveying the idea with blunt, arrogant/conceited speech.