I've never used chems, other than to get a temporary boost to skills.
Stuff like slow motion, extra action points, and especially 25% extra damage is incredibly useful, the latter especially so for sniping. There really is no downside to using them when I almost never get addicted and can easily fix any addiction with seventy-five caps. Once again, I make over nine-hundred caps every time I cap a Prime / Veteran Legionary, a Fiend, a White Leg, a Khan, or any other kind of raider. Those guys are everywhere.
Is this with the perk that increases the amount of caps you find, or not?