A few or all have probably been mentioned in this thread but reinforcing it.
Tsukihime (not that it had one to begin with)
Fate/Stay Night (now that I recall, this is getting a new adaptation by Ufotable, not sure if it's been confirmed which route or amalgamation though.
Berserk(the movies are way too rushed and cut out too much)
Jojo is getting the treatment for part 3 which is awesome.
Megaman, can't recall if that was an anime or cartoon
Blade Of The Immortal
And probably a lot more that I can't recall right now, there's been no shortage of mediocre adaptations that could have been great or those that branched off into their own thing.
edited 15th Dec '13 1:25:21 AM by Jeorg
A love that crushes like a mace.