The classic Batman story Knightfall involved Bane throwing villain after villain for Batman to defeat in order to wear him down both physically and mentally. This results in Batman being easy pickings for Bane who proceeds to deliver a No Holds Barred Beat Down to Bats, breaking his back.
The final battle of Transformers: Last Stand of the Wreckers is the remaining Wreckers Zerg Rushing Overlord in a desperate last ditch attempt to take him down, not because they couldn't come up with a better strategy but simply because that was the only way they could hope to beat him. It still takes Ironfist blowing him apart from the inside and Impactor giving one last beatdown to finally put him down for good. Even then by the end of the fight Impactor, Verity Carlo, Ironfist, Kup, and Perceptor are the only Wreckers who aren't dead or horrifically wounded.