* BestKnownForTheFanservice: The most known scene of the film is when Sally fakes an orgasm in a crowded restaurant -- possibly approaching AllThereIsToKnowAboutTheCryingGame.
* FamilyUnfriendlyAesop: Men and women can never be just friends. Also increasingly a case of ValuesDissonance as people of both genders become more integrated.
** Averted as Harry and Sally were friends for a long time before falling in love. It also proves Harry's assertions wrong, as he's friends with Sally because they are genuine good friends, and he does not show any signs of wanting to have sex with her during their friendship, and only barely when he falls in love with her.
* HilariousInHindsight: Harry is seen reading ''Literature/{{Misery}}'' by Creator/StephenKing. Guess what Creator/RobReiner's next film was?
* MemeticMutation: "When ______Met ______" . Almost thirty years later and people will recognize this as a riff on the movie's title.
** "[[DeadpanSnarker I'll have what she's having.]]"
* OneSceneWonder: The director's mother saying "I'll have what she's having" is remembered maybe even more so than the film is.
* TearJerker: Harry and Sally's coping with their failed relationships can hit close to home for people who have gone through that kind of grief. Both claim to be "over it" until innocuous events trigger their sadness and it all just comes pouring out at once.