These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Humans themselves are presented this way. Most aliens despise or hate them as an upstart rogue species that never had a proper upbringing, but even in-universe a few view them as The Woobie.
The Karrank%, good God. Their patrons, the Nr~klat, warped their bodies and minds so severely that every one of them is born incurably insane, and they live their whole lives in horrendous mental anguish. They were allowed to "retire" to Kithrup, but they're near the bottom of the legal and social totem pole and appear to be physically unable to leave the planet, thanks to how they've continued to evolve.