These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
During the "Things You Should Never Run Into A Room And Say" bit, one audience member sent in the clip of him saying thus: "Dude, 9/10, y'know what tomorrow is! Party at my place!" The Studio Audience's reaction was exactly this, with half-laughter, half-groaning.
Nightmare Fuel: The many times people injure themselves doing stupid stunts (usually involving either a trampoline or a skateboard) and end up snapping their limbs at 90 degree angles. Sometimes it'll even come with a Gross-Up Close-Up.
An episode presented us, during the Video Breakdown segment, with a lovely video of a young girl playing with a dead squirrel, half-naked, while her father laughed as he videotaped it. Tosh kept repeating (more or less) "What the fuck is wrong with her parents?!"