These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Mary Sue: Critics of the comic accuse Anne of being this. Citations include being the Author Avatar, the most powerful character in the cast, and being able to overcome powerful enemies and obstacles with minimal effort. Also, the consequences of her actions, no matter how dire, are usually brushed off, forgotten (thanks in part to Tandy Gardens having the attention span of a bag of peanuts), or seen as a benefit rather than a detriment.
Moral Event Horizon: What Miranda did to Ivan. Possibly averted, as she's shown some genuine conflict with her decision. In particular, the fact that she not only included Ivan but also two innocent bystanders as part of the "punishment" more or less ruins any chance she had at sympathy. It doesn't help that she tries to hold Ivanaccountable for their predicament, given that she never gave a straight hint that her curse would afflict potential bystanders.
Unfortunate Implications: A common criticism the comic receives: It appears everyone is better off being a girl. Which is eventually averted with Ivan and his friends. Not only is Ivan himself miserable, the punishment he has received seems to be further motivating him to continue his investigation. His friends are taking it slightly better, as while they have shunned Ivan, they're at least happy that they're not working through this change alone.