These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
The Woobie: You have to admit, Nikki has been through a lot of stuff, and it doesn't help when her rejections from the Professor and his treatment of her are seriously played out. One episode has her at a support group for the lovelorn, where she has a Break the Haughty after claiming she doesn't need to be there before the group leader questions her if she and the Professor are really together, breaking her down as he questioned if he even acknowledges Nikki.
Ironically, one episode had her so stressed out that she didn't even acknowledge the Professor himself.
She also discovered that she was adopted on national television in Family Ties and Lies, because her uncle was so determined to win the prize money.
The final season opener has her lonely and depressed over the Professor getting married and Kim leaving for Harvard, while her wedding plans in the final episode start to fall apart.
It doesn't help that in another episode when her romance novel (with the Professor as the main character, of course) becomes a big hit, Shaquille O'Neal himself shuts everything down by claiming the Professor is nothing but a fraud and a playboy, which is kinda true, with Shaq showing a photo of the Professor out with several women. The Professor then has the audacity to retaliate with the fact that with his publicity, "Why need one woman when you can have them all?". This repulses Nikki's fans and prompts them to start a book burning.