These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
It Was His Sled: Elly Patterson is murdered. A well known plot point now, a huge plot twist back when the story was written.
Moral Event Horizon: That John crossed it everyone can agree on. When is a more debatable question, but there are three strong candidates: 1)When he refused to seek help for an increasingly unhinged Elly, 2) when he attacked Elly upon finding out she has an illegitimate daughter, and point blank revealing that Michael's not his biological son, and 3) getting involved with Kortney (who in the comic had stolen from Elly's bookstore and threatened to beat up April over it), bringing her to Elly's funeral, and introducing her as his fiancee. For what it's worth, a few characters find his MEH to be finding that Elly was abusing and starving Edgar hilarious.
Elly retroactively crossed it when Elizabeth and Anthony figure out she was behind Elizabeth's Attempted Rape to invoke the Rescue Romance trope on Anthony. Funny thing was, though, Elizabeth thought it was Anthony's MEH until she realized Elly set it up.
Nightmare Fuel: Imagine living in the same neighborhood as an increasingly unhinged Elly and unable to do anything about it cause the law won't do anything about it until she's an actual threat.
The scene where Elly tried to sew on Butterscotch.
Rescued from the Scrappy Heap: One of the things this fanfic does well is rescues a lot of characters from the Scrappy pile, and turns them into sympathetic characters, Anthony being the biggest one. Even Therese can technically count, cause Ensemble Darkhorse or not, she was written in the comic strip as The Scrappy.
Claire tried to reach out to Elly but was rebuked with a hiss that Elly tried for years to clean Claire's dirt off her.
Finding out that it's possible Deanna's miscarriages were an effect of being born in Millborough, and Elizabeth wondering if she could bear another healthy child...which only reminds her that she and Anthony have not had a child together.
Claire's mother's death
Elizabeth and Anthony sharing a bed for the first time since James's birth, and Anthony asking her out on a date.
What an Idiot: Gavin spoke out against the investigation into whether building Millborough on a radiation site had an effect on health. Perhaps he should have remembered that birth defects were one of the symptoms, and that one of his more significant clients is a neonatal clinic.