These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Alternate Character Interpretation: The way Billy idles around in back, blushing during the saloon girls' dance while all the other characters cheer on, front row center. Does he have a thing for one, or all of them and is too bashful to stick around? Has he already got a steady back home? Or is he just a butt-cowboy? Not really elaborated upon any further than that.
That One Boss: Chief Scalpem. He block BULLETS with a pair of knives and throw a flurry of 'em at you which are frustrating to dodge.
It gets better: those knives have unpredictable hitboxes. One YouTubeNo Damage Run notes (after a knife passes straight through his character without injury), "Don't fucking ask how that didn't fucking kill me right there."
El Greco will empty your pockets if you're not quick on your feet. You'll spend a lot more time repositioning yourself away from his whip range than you will actually shooting him. Did I mention he blocks your bullets with a door hatch?
But once you get around his pattern, he is easy, Scalpem is almost completely random.