These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Anvilicious: Pushes this from time to time, as a number of arcs tend to end in a character getting a lecture about how stupid they are (or how wrong they are for their views or stance on the issue at hand).
Complete Monster: Avogadro Pompey stands out as a Complete Monster even compared to the Jerk Ass cast of : he kept Pepito as a sex slave, psychologically and physically abused his nephew, and set Kharisma up to take the rap for a murder (his own, as a matter of fact) which she didn't commit.
Fan-Preferred Couple: Davan and PeeJee. Devoted to each other, a obviously much better relationship than most of his girlfriends and her boyfriends (both of which are usually crazy or cheating or both) but they stop at Platonic Life Partners. Milholland gets a lot of mail asking if Davan and PeeJee are going to hook up, so he did a Q&A strip saying no, the woman whom PeeJee is based on asked him not to, and he doesn't see it working, which means more than any amount of "They're meant to be!" emails. Of course, this isn't helped by the amount of Ship Tease Randy puts into the comic to begin with, which he's admitted to putting in to mess with people.
Hollywood Homely: Despite looking pretty average when compared to the rest of the cast, people treat Davan as if he is one of the most disgusting, grotesque person in all of human creation. One girl actually started screaming in fear when she saw him for the first time. Granted, said woman was Kharisma and the jokes about Davan's appearance disappeared after the first few years.
Jerk Sue: A resultant of reaction between Slice of Life and supersaturated Comedic Sociopathy solution. The only question is "who?", with Davan and Aubrey being main candidates, or even the whole core cast, especially when they work together. Milholland admits that they should really all be in jail.
Magnificent Bastard: Randy himself. If you're going to send Randy flame emails, make sure that googling your email address doesn't lead to your phone number/address/embarrassing information about you. This is partly on the YMMV page because this makes him either a Magnificent Bastard or just a pettyJerkass depending on how big a fan of his you are.
"Damn you Milholland!" is the fandom's catchphrase for the ability to contrast the Comedic Sociopathy and Black Comedy with the occasional heartwrenching story climax.
In-story, Fluffmodeous is starting to shape up like one. Imaginary, perhaps, but still terrifying.
Mike, a whiny, misogynistic jerk who blamed everyone else for his failures. Slowly, he realised that everyone thought he was a asshole, and that they were right and started to change. Even with some backsliding, he was trying to do the right thing and became much more sympathetic.
Kharisma, a dimwitted Rich Bitch who lost the money and kept the attitude, entirely self-centred and hated the ugly "little people". Then she scarred her face, went to prison, faced being killed there, was broken out and now leads an off-the-grid semi-criminal life that has knocked the attitude out of her and also made her a sympathetic character. According to Randy: "I have to say I'm surprised by how many people actually look forward to Kharisma strips and more stunned it's not to see her suffer."
They Wasted a Perfectly Good Plot: There are a lot of side characters in the strip, and a lot of them have these very interesting little bits of history to them, and have complicated private lives. Many of these situations are only explained in Info Dump exposition instead of shown, and thus we miss out on some very good bits. Of particular note are the mess that Davan's ex Eva's lift turned into (repeatedly getting back together with an abusive boyfriend while her ex-fiancee chases after her), and his other ex Celie and their weird history (she dumped him once he was no longer "useful to her", and spent their last days setting up her next relationship, then left Monette with an apartment lease and bailed on everyone, only to reappear in a few mini-arcs to interact with the cast).