These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: Ratchet & Clank: Going Commando
Anticlimax Boss: Amusingly, the final two bosses can both be taken down before the fight even begins, due to them both appearing on the map before the battle and still being damagable in this state. See here and here.
Demonic Spiders: The Y.E.T.I. on Planet Greblin. They are everywhere, highly durable, annoyingly cheap, and will do their best to prevent you from getting moonstones, often attacking in large groups. Some developers admitted they were coded in a rush and break some of the enemy guidelines they set, like short attack telegraphing and constantly attacking from behind. This actually got a Medal of Dishonor made for the studio, called the "Snowbeast Award" for whoever made the worst thing in a game made the previous year.
Designated Hero: Angela Cross. After The Reveal, she's treated as a misunderstood hero who's been thwarted by unsuspecting dupes. Though she was a Well-Intentioned Extremist, her crimes up to this point include kidnapping and holding Clank hostage, repeatedly trying to kill Ratchet, and generally just acting like an actual villain. Though we learn she was forced to resort to extreme measures to stop Fizzwidget from releasing the Protopet in its current state when he fired her and refused to listen to her concerns, her actions cross the line from extremism to villainy quite easily.
Even Better Sequel: Quite apart from Ratchet's improvement in professionalism and character, the weapons are more serious yet still creative, the number of worlds and gameplay elements increased, RPG-like elements such as the upgrade features were added, and the wrench controls became a lot less cumbersome. There's also a ton of new features and gadgetry, and even the Clank sections underwent some major changes.
The Bouncer can be this in all but the very last levels. It does massive damage on the initial blast and lets loose mini-bombs that seek out remaining targets and explode for additional damage. Its only shortcoming is that it has a hard time hitting flying enemies, but anything on the ground is toast. The final boss can be killed in a couple minutes just by bombarding it with Bouncer bombs.
The Plasma Coil is an okay weapon at first, hitting a primary target for decent damage and shocking nearby enemies when it hits. However, it upgrades into the Plasma Storm, which fires an orb of electricity that shoots out lightning at anything it passes. A single Plasma Storm shot is enough to clear entire rooms full of enemies.
The Shield Charger is a magnificent example of Magikarp Power. It's initially weak and almost useless, it protects you from damage and does minor damage to enemies you touch. Stick with it though and it becomes the Tesla Barrier, which shoots lightning to zap any enemy that gets close to you, and it does good damage with it too. It noticeably helps against the above mentioned Demonic Spider Y.E.T.I.
As last time, the RYNO II pretty much annihilates anything you aim it at.
The Sheepinator makes fighting Protopets hilariously easy, killing them without using any ammo whatsoever (so you could save your ammo for the harder enemies of the level). The Black Sheepinator is even better, killing them faster and also turning them into sheep that explode.
Goddamned Bats: The Protopets. They keep reproducing if you don't get every single one of them and you often encounter them in groups.
Goddamned Boss: Megapede is not difficult to beat, but it has a large health bar, moves around the arena all the time, deploys irritating bombs en masse, and when whittled down by a powerful weapon, deploys mini-tanks with a difficult-to-avoid attack. The RYNO II doesn't help in this case because it keeps missing it, so you'll need weapons with Lock-On Mods.
Good Bad Bug: Using the thruster boots on the ice planet while being attacked by the Yeti's can cause Ratchet to dissapear with only his shoes, helmet and clank being visible. In this state he is immune to damage, which means you can run around collecting Moonstones or beating Yeti's at your pleasure.
Ho Yay: In the first cutscene, Ratchet is told he will learn a number of bizarre skills to become a commando, including ballroom dancing. Complete with an image of him in a fancy suit, dancing with a dress-clad Clank.
It Was His Sled: The Unknown Thief's true identity, being a female lombax named Angela Cross. Of course, the series' "official wiki" does not care with the spoiler policy, so only a few fans would really not know about this before playing the game for the first time.
Moral Event Horizon: Captain Qwark, much like in in the first game for siding with a planet killer for publicity and money, comes dangerously close to crossing this line again in this game, by kidnapping and impersonating a corporate CEO, and willingly unleashing a killer pet upon billions of lives so he could avert the threat and take credit for it, and attempting to frame Ratchet, Clank and Angela for the catastrophe. And barring his plan horribly backfiring on him and getting him eaten alive, and being stuck in a humiliating, painful disposition as a Megacorp test dummy, he practically gets off scot free. Fortunately, he manages to redeem himself in the next game
The Scrappy: The New Age Mystic for being generally unhelpful and requiring the hard-to-get Moonstones just to do something.
The "Wrench Ninja II" skill point is just as bad, as the enemies on that planet will often kill each other before you even reach them, and it's nigh impossible to hit some enemies without getting a few scars for your trouble.
Woobie Species: The one-eyed robots seemingly can't catch a break. They get blown up in a commercial and eaten by mutant squirrels on Todano, killed by security robots on Aranos, and massacred on their home planet, Damosel. Two skill points involve keeping them alive despite the hordes of enemies waiting to get them.