* AnticlimaxBoss: After the exhilarating final fights against Dr. Nefarious and [[spoiler:Azimuth]], you're treated to an optional [[BonusBoss bonus rematch]] against Lord Vorselon. While its a fun fight, its also a lot easier and less thrilling than the previous battles, and if you have the fully upgraded R.Y.N.O. V (which you likely will by that point, considering it constantly levels up when used in boss fights), you can cheese the whole fight in less than a couple minutes. Its also PlayedForLaughs, as the final phase simply involves Ratchet [[ZeroEffortBoss stepping on Vorselon's disembodied head.]]
* BestBossEver: [[Series/{{Jeopardy}} Answer: Daily Double!]]
** The [[ClimaxBoss penultimate fight against Dr. Nefarious]] is on par with your previous confrontation with him in ''[[VideoGame/RatchetAndClankUpYourArsenal Up Your Arsenal]]'', and ranks as one of the best boss fights in the entire series. Its a truly thrilling, breakneck paced three phase fight where Nefarious throws everything he's got at you and more, with combat (and some hoverboot segments) that ''will'' keep you on your toes, even with the [[GameBreaker R.Y.N.O. V]] on hand.
** And immediately following that is the climatic final boss fight against [[spoiler:Azimuth.]] Its a tense one on one battle where you have to fight tooth and claw and use everything in your arsenal to bring him down, all while the Great Clock is falling apart around you. No gimmicks, no other enemies summoned, just pure teeth clenched combat as you fight to determine the fate of all existence. Its basically the [[Film/RevengeOfTheSith "Anakin Vs. Obi Wan"]] moment of the entire franchise, and its a truly challenging yet extremely fun fight.
* BreatherBoss:
** The fight against Cassiopeia at the Valkyrie Citadel. Her attacks are easy to dodge and she has mediocre stamina. Even on hard mode, she won't give you too much trouble.
** The fight against Lornock Argos in Gimlick Valley, especially relieving considering [[ThatOneLevel how hard the level is.]] He commands a slow moving star cruiser that has a ridiculously simple and predictable attack pattern and is a huge target for your weapons. If you have the Judicator and Doom Blades, he goes down faster than a bill to save a rainforest. Even on Hard Mode, this guy is a complete joke of a fight.
* DisappointingLastLevel:
** The return to Dr. Nefarious' base [[{{Railroading}} cuts you off from playing the bulk if the level]] and only consists of a floating platform trip and a brief walk (with some enemies sandwiched in) before you fight Nefarious himself.
** The final visit to Lord Vorselon's ship consists of a turret showdown with a few waves of enemies and an easy Omnisoaker/bolt crank puzzle before you face Vorselon one last time.
* EarWorm:
** Like in ''Tools of Destruction'', any track the Groovitron plays will get you thumpin'.
** Just about every piece of music that plays on Pirate Radio while you're exploring outer space.
* EvenBetterSequel: When compared to the previous game, and for that matter, any of the games between ''Up Your Arsenal'' and this one. Not only it improves on the gameplay of it's predecessor ''Tools of Destruction'', but it introduces several new features like the ability to travel around the space with the spaceship as opposed to a PointAndClickMap like other games, as well as having two kinds of gameplay between Ratchet and Clank, great level design, more creative weapons, more boss fights, and the return of [[BreakoutVillain Dr. Nefarious]] as the BigBad, the result is a game that is widely seen as the best of the ''Future'' sub-series. It's been so acclaimed that, if there's one game that easily reaches (if not ''surpass'') the quality of ''Up Your Arsenal'' as the best game in the franchise, it would be this one.
* FridgeLogic: In the Recap cinematic, Captain Qwark stated his reason for not being present in ''Quest For Booty'', and that was for shooting for a new holo-film. However, Captain Slag and Rusty Pete both had parts in the film as well, and they both had significant roles in ''QFB''. How could they manage the time to film alongside Qwark as well?
** Solution: Qwark was also filming ''Unicop'' in-between the two games. It might have been filmed first, while ''My Blaster Runs Hot'' was filmed afterwards. This would make sense, considering the amount of time and costs it would take to finish ''Unicop'' because Qwark plays a unicorn in the film, while he's just playing himself in ''My Blaster Runs Hot'', so there's a good reason who the latter was released, first.
* GameBreaker: The R.Y.N.O. V continues the series tradition of ridiculously overpowered bonus weapons by being an oversized machine gun and missile launcher mashed together, capable of eviscerating any enemy and any boss outside of Nefarious and [[spoiler:Azimuth.]] in seconds. It even turns the extremely hard "Overkill" challenge of the Raritanium Tournament into a cakewalk. And best of all, it upgrades as you fire it on bosses, meaning you can max it out just minutes after acquiring it! The only downside is that it chews up ammo insanely fast, and you can't acquire all the holo plans for it until just before you fight Dr. Nefarious. On the other hand, you can start [[NewGamePlus Challenge Mode]] right afterward...
* GoddamnedBoss:
** The VX-99 Hoverdrone that you fight in Axiom City. Its not a hard fight, but it can be annoying due to it constantly spamming lasers and pulling some cheap and hard to dodge manuevers on you.
** Any fight with a Hydra Tank. While you can mow down their health quickly with the right weapon, they have a large variety of fast and hard hitting attacks. And during the battle of Gimlick Valley, you fight two of them in the same small area!
** The War Grok arena fights aren't particularly difficult, but they require fast reflexes and a lot of patience due to its [[DamageSpongeBoss high stamina]], especially during the fight where you fight it with only your wrench. The fight where it tag teams between it and a Hydra Tank can be frustrating, too.
* HarsherInHindsight: After you've seen [[spoiler:Azimuth go nuts and kill Ratchet in his quest to rewind time]], his unceasing ranting throughout the game suddenly sounds much more unhinged than it did on your first playthrough.
* HilariousInHindsight: The Valkyries are SpacePirates in this adaptation, and one of the leaders is named Carina. ''Film/PiratesOfTheCaribbeanDeadMenTellNoTales'' introduces a character named Carina, who becomes a pirate towards the end [[spoiler:and is the daughter of Captain Barbossa]].
* MoralEventHorizon: [[spoiler: Alister Azimuth ''kills Ratchet'' at the end of the game. Shortly afterward, he becomes the final boss and nearly destroys the entire universe. However, since Ratchet's death is undone by Clank and Alister finally sees the error of his ways, sacrificing himself to prevent the destruction of the universe he almost brought upon it, fans generally don't consider him too far-gone to be denied [[RedemptionEqualsDeath posthumous redemption]].]]
** "Unnecessary Initiative Omega 91" is this for Cassiopeia, given she spends the entire time trying to kill Ratchet and orders the other Valkyries [[spoiler:to execute Clank]]. And like Courtney Gears before her, Cassiopeia is quite sadistic over this.
* MostWonderfulSound:
** The [[StockSoundEffect old school laser sound effect]] that plays when you have the Constructo Gun set to shoot laser beams.
** The R.Y.N.O. V plays the finale of [[Music/PyotrIlyichTchaikovsky Tchaikovsky's]] [[CrowningMusicOfAwesome 1812 Overture]] every time you fire it. A fitting theme for the most powerful weapon in the game!
* RescuedFromTheScrappyHeap: The Buzz Blades, which were [[ScrappyWeapon one of the worst weapons]] in ''[[VideoGame/RatchetAndClankFutureToolsOfDestruction Tools of Destruction]]'' due to its abysmal damage rate, pops up again as a much more useful weapon here since its damage properties are much higher off the bat, and upgrading it makes it one of the most powerful weapons in the game, and its a real lifesaver in Hard Mode. Its even an effective weapon in boss fights, including the final two. The only downside is its low ammo combined with its fast firing rate, but that gets mitigated with upgrades.
* ScrappyWeapon:
** Mr. Zurkon, lovable as he is for his gleefully bloodthirsty personality, simply isn't a very good weapon. While he gets the job done fine on anklebiters, he immediately runs into trouble with larger foes. His very poor damage ratio means it takes forever for him to kill even one mook, much less several, and he's about as useful as the [[VideoGame/RatchetAndClankGoingCommando Clank Zapper]] in boss fights. [[ArtificialStupidity His A.I. is very spotty]], and he'll often miss or ignore a target thats clearly in his line of sight or ignore anklebiters in favor of harder to kill larger foes, and his range of fire is very short, meaning he's flat out useless against flying or long range enemies. And he has a tiny ammo capacity on top of that. He becomes all but useless when you reach the later levels.
** The Rift Inducer 5000. Fans of [[VideoGame/RatchetAndClankUpYourArsenal the original Rift Inducer]] will be sorely dissapointed that this incarnation is a heavily flawed follow up. While it can swallow up huge enemies and deals good damage, its crippled by two major flaws: first, its an ''extremely'' situational weapon. The rift only stays in one spot, which makes it extremely impractical as a crowd control weapon in a game where enemies are often spread out wide and numerous in numbers, meaning it can only focus on a tiny area of enemy territory at any one time, and you can't launch multiple rifts to make up for this--theres an extreme delay between when you can fire another rift. And its extremely small ammo basically means its only practical for taking down the odd large enemy.
* ThatOneAchievement:
** The "My Blaster Runs Really, Really Hot" trophy, which requires you to get 10,000 points in the game, which is easier said than done due to its [[NintendoHard tough difficulty.]]
** The "Master Blaster" skill point, requiring you to keep the blaster in red without overheating for a full minute in the "My Blaster Runs Hot" mini game.
** The "Flawless" skill point, which requires you to complete the final Battleplex challenge, "Overkill", without getting hit once. That's 18 waves of enemies followed by 2 (albeit easier than the waves) bosses. Even with a max level RYNO V there's still the possibility of certain enemies messing up your movements, such as Thrasher robots who can pull you towards them, or others sneaking in hits, like clusterbomb Argorians who wield weapons that can be either flung far as explosive projectiles or quickly swung into the floor as a melee weapon.
* ThatOneLevel:
** Krell Canyon has a part during the first stage where Ratchet must move two platforms over a bottomless pit to bypass a tetromite nest. Unfortunately, it is very possible for the tetromites to reach the other side and wait for Ratchet to leap over to them, making it almost impossible to reach water before his HP reaches zero.
** Gimlick Valley is a tough and near overwhelming level due to the sheer number of resilient enemies present. And its topped with a fight against two Hydra Tanks fighting in tandem! On the other hand, [[PeninsulaOfPowerLeveling it is the best place to max out weapons]].
* ThatOneSidequest: Beating the Raritanium tournament in the Agorian Battleplex, with the climatic "Overkill" challenge being the hardest part of the entire game, even more than either of the final boss fights! Its 18 waves of dozens of tough enemies that do not let up on you, health drops are very scarce, and its topped with two more waves consisting of a back to back fight between the War Grok and a Hydra Tank. Unless you acquire the [[GameBreaker R.Y.N.O. V]] (which lets you cheese the whole event as long as you stay on your toes and constantly refill its ammo on the run), do ''not'' attempt this challenge without the Hyperflux armor and a heavily upgraded arsenal.
* UnderusedGameMechanic: The Constructo Weapons are a great idea and fun to use, but the problem is simply that they didn't go far enough with it. With only three Constructo Weapons and 21 upgrades to find total for all of them, theres not all that much variety to them or their functions, and the upgrades aren't particularly balanced either, meaning you'll clearly favor some upgrades over others. Compared to the weapon modding in games like ''VideoGame/RatchetDeadlocked'', it comes off as somewhat shallow and gimmicky.