- Bizarro Episode: one issue of the comic, "La Mummia" (The Mummy), had nothing to do with Rat-Man. It was a parody of the Mummy series of films starring ancestors of Aldo and Giuda, characters from Ortolani's comic series "Venerd́ 12".
- The last episode of the animated series, Saving and Imagination. Basically, the budget for the series is reduced to 199 dollars, so Rat-Man haves to cut short on stuff (Wraparound Background during driving scenes, recycling backgrounds from old episodes, reducing the bad guy's powers, Stock Footage abuse, crude backgrounds, than removing colors and backgrounds and replacing the soundtrack with cheap midis...). The episode ends with a Synchrovox animated Rat-Man whistling the theme song over the credits.
- Hilarious in Hindsight: Guess who is sometimes called The Great Ratzinga in Italy.
- Holy Shit Quotient: Aptly, very high towards the end of "The Last Secret": The Buffoon is in fact Noctule?! Wolf is Spectre's father?! SPECTRE IS KIMMY?!
- And then recently topped during the "I Vendicatopi" story arc (initially a Shallow Parody of The Avengers), when Rat-Man discovers that his hero Mr. Mouse created not just the superheroes but also the supervillains, and all in the name of profit.
- What do you mean Rat-Man is Walker's biological son? What do you mean he'll be the next incarnation of the Shadow?!
- Shallow Parody: Rat-Man began as a Batman parody, but the more the stories went on, the more Ortolani removed elements of it, such as Rat-Man being a millionaire, his Rat-Mobile, his sidekick Ṭpin, and so on. Justified since Ortolani wanted his hero to be more like a metropolitan vigilante a la Spiderman.
- Leo himself even admitted he never even saw Tim Burton's Batman in its entirety.
- Venerd́ 12 (Friday the 12th), another series by Leo published on the Rat-Man magazine, has nothing to do with Jason Voorhees besides the title and the fact that the protagonist is a hideous man turned into a monster who lives alone and hides his face under a blank mask.
- Tear Jerker: There are some, like the scene of Thea's "death".
- What Do You Mean, It's Not for Kids?: it's what happens when your series takes the innuendos in Animaniacs... and runs with them. Obviously, this gets a Lampshade Hanging whenever a Family Unfriendly Character such as Cinzia Otherside shows up:
Rat-Man: "Cinzia, there are kids out there."