These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Moral Event Horizon: Some people consider Fukiko's horrifyingly cruel Hannibal Lecture to Rei in the manga to be this. Specially because Rei ends up commiting suicide few afterwards.
Narm: A non-drama example: Aya Misaki's horrible puffy hair. May have been in vogue in The Seventies when the series was written, but now...
As well as the ridiculously exaggerated faces she makes after Mariko slashes her with her boxcutter.
Values Dissonance: Lots of people are weirded out when the Seiran students make such a huge deal of Nanako's mother being re-married to Professor Misonou (aka Takehiko's estranged father), but it makes more sense when we remember that the Japanese society's stance on divorce, adoption, and Sins of Our Fathers are pretty different to the ones in the West. And there's also the fact that this particular manga was written in The Seventies...
Wangst: Lots of it, but especially Fukiko, who cannot get over the fact that Takehiko didn't come to her violin recital when she was 12... which happened six years ago.
Lampshaded by Rei in episode 25, when recalling her and Fukiko's first meeting. Young Fukiko was in tears over being shabbily treated at a friend's party (read: she didn't like the seat she was given) and young Rei was all "... is that ALL?!"
What Measure Is a Non-Badass?: If you watch this series on YouTube, PLEASE be careful while reading the comments. Lots of people there love to bash Nanako and call her "weak" or "stupid" for not kicking off her bullies.
Nanako and Rei. Poor little Nanako, so sweet and so kicked around by life itself. And poor Rei, so utterly broken ever since she was a little girl. Also, episode 15 brings a character we didn't know about, then breaks her, and makes her this. Poor, poor Junko.
Jerk Ass Woobie: Mariko. Utterly clingy and possessive of Nanako, to homicidal and self-destructive degrees, and can be a bitch to Tomoko in the beginning. She's also among the few willing to protect Nanako from bullies and help her in the Sorority, and is genuinely fucked up from her parents's MESSY divorce, which drives her to almost kill herself. Not to mention— gosh, when she shows a sweeter side, you almost wanna say "Mariko why so moe"? And surprisingly, Aya Misaki becomes a Jerk Ass Woobie late in the series.
Iron Woobie / Stoic Woobie: Kaoru and Takehiko. Kaoru does what she can to deal with her woobielicious best friend Rei being totally broken and her own ailing health; meanwhile, her boyfriend/eventual husband Takehiko almost always smiles kindly and tries to be a good friend, despite how he can't tell Nanako that he's her stepbrother aside of her pen-pal, which puts quite the spin in their interactions, as well as his own relationship with Kaoru. (And we're not counting the manga, in which Kaoru actually dies a while after they reconcile...)