These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Monmow disease (and especially the part of the plot located in South Africa, where "it's impossible a white person would be contaminated"...) takes on a whole new meaning in the context of the AIDS pandemic.
And Urabe's antics are retroactively made even more chilling by the fact that he looks like a young Gendou Ikari.