These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: Nip Tuck
Darkness Induced Audience Apathy: The show is full of dysfunctional, rather unsympathetic characters who grow more and more dysfunctional and unsympathetic as they (poorly) navigate a seemingly endless series of increasingly improbable, horribly disturbing situations.
Faux Symbolism: AOL TV says that by the Season 6 finalenote actually the finale of the first half of the sixth and final season episode's end, "watching Wesley [Clovis] die from lethal injection brought forth all sorts of metaphors, the most obvious of which being Jesus. Wesley lay there, arms outstretched on the the cross-shaped surgical table, bloodied from the staples in his stomach (his own crown of thorns), an innocent man, slowly dying for someone else's sins", and that includes the sins of Matt, Sean, Christian, the murder victim's father, the courts, and "the guy who actually perpetrated the crime Wesley was accused of." Not to mention the fact that Matt's denial of Wesley's innocence at the last moment in exchange for his own freedom could be relevant to St. Peter's denial of Jesus for the safety of his own life.
"Funny Aneurysm" Moment: In the Season two finale Gina, who's had her face sliced up by The Carver, jokingly tells Sean and Christine before surgery, "I don't wanna look like the Joker."
Ho Yay: To the point that season four made an entire plotline out of Christian wondering if he was attracted to Sean.
Informed Wrongness: Erica (Julia's mother), is treated as venomous bitchy Mother-In-Law character in nearly all of her appearances, and is wailed on for aggravating Julia's sense of insecurity. The problem is, in most of her appearances, Erika is trying to get Julia to stand up for herself and be proactive instead of wallowing in a giant pool of Wangst over how unsatisfied she is with her life. Sure, she's a bitch, but a comparatively minor one considering Julia's husband regularly engages in in-your-face cheating as petty revenge. It's difficult to see her as a bad person for saying Julia wasted her life by not becoming a doctor when Julia herself feels the exact same way.
There's also the way Colleen Rose killed a rival talent agent. She jammed the hose for a teddy bear-stuffing machine down his throat and flicked it on, then finished her new creation by pinning two button eyes onto his.
In one episode, the patient is conscious during her surgery, can feel all of the pain, and screams and begs for the doctors to stop in voiceover.
Seasonal Rot: The majority of the fanbase believes season 3 was trash, whether or not it ever recovered for any period of time after that is up to debate.
Squick: What the show is built on. Plastic surgery is inherently kind of squicky, but this show manages to gross you out every episode. An recent example from the fifth season was a rejected client carrying out a DIY mastectomy with a motorized knife in the middle of a waiting room.
An older gay man who has his boytoy go under the knife to make him look more like himself as a young man.
A broker has his adopted son go under the knife to give them more of a family resemblance. Seems harmless enough, right? Then you learn he did it because his clients wanted the two to look more alike because seeing a man sodomize his biological son is more exciting than seeing a man sodomize his adopted son.
A lottery winner wants a list of surgeries done on herself and her daughter and husband. Including breast implants on her daughter and a penis extension on her husband. Later shocked when step-father and step-daughter try their new gifts out on each other...
A woman wants too look more cat like, including spots... (like several cases in the show, Truth in Television)
Tear Jerker: The death of Megan O'Hara in season one. Don't you dare say that you didn't become teary-eyed when this happened. The lighting, the tears in Sean's eyes, Rocketman playing in the background...
Also in Season 6, the execution of Wesley Clovis in spite of his innocence that was denied and ignored by the courts and by the murder victim's father who only wants vengeance in the form of "justice" satisfied. Nothing gets this one sadder than this, with the sad music playing in the background.