These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Crowning Moment of Awesome: Bandit challenging a guy about twice his size to a boxing match. He gets clobbered, but being beaten to a pulp and still being able to stand is undoubtedly awesome.
Nip's entire plan in exploiting a very small loophole in Michael Moby's movie contract and succeeding at it.
Designated Monkey: Gilly Gopher, of course. While other characters may have defeats and setbacks, Gilly has never had (and will never have) anything but. All of the other recurring characters in the strip have had at least one victory, Gus Guthrie included; Gilly isn't even allowed to make bad jokes without immediate punishment. Gilly has even acquired a small, sympathetic following among the readers since the writer started introducing new characters to beat him up.
Real Women Never Wear Dresses: Respect isn't very high for women that box or wrestle in Malarky County, and Bandit gets badly injured trying to defend the honor of a female boxer named Sierra.
On the bright side, she was touched that he made the attempt.
Values Dissonance: While not common in this strip, it does show up. Women who actually call themselves Feminists come in for a lot of abuse... but the female characters in the regular cast are strong-willed, sensible, and able to take care of themselves... which is what a lot of actual feminists think a female character should be like. (The hard part is whether this counts as Values Dissonance for the strip or for Feminism...)