- Anvilicious: Humans have a shocking capacity for hatred, and that is a Bad Thing. This is one of those Aesops that's perennially relevant...
- Complete Monster: Dr. Philip Decker is far more evil than any of the actual monsters in the film are. He masquerades as a renowned psychologist, but is actually a masked, bayonet-wielding serial killer who butchers families (including the children), women he comes across, and anyone else he can get his hands on. He sees himself as a Death-like figure on a mission to stop the continuation of mankind. After Deckerís psychiatric patient Aaron tells him his dreams of the Nightbreed civilization, he frames Aaron for his crimes and gets Aaron killed by the police. When he learns of Aaron's resurrection and the existence of the Tribes of the Moon, he tries to exterminate the civilization of Dark Is Not Evil magical creatures as the ultimate extension of his mission to cleanse the world. A depraved and hypocritical Knight Templar with an utter contempt for humans and Nightbreed alike, he earns the fear and disgust of everyone who's unlucky enough to see his true face.
- Fan Disservice: The character of Shuna Sassi is a walking example of this both in-universe and to those who view the film.
- Hilarious in Hindsight: Shuna Sassi impales with her quills a soldier named Kenny.
- Also, some of the Midianites look like the sewer mutants from Futurama.
- Ho Yay: Peloquin's... hunger for Boone carries a metric ton of Does This Remind You of Anything?.
- Leroy Gomm and Lude are...rather close. Apart from all the shoulder-touching, during Boone's dream there's a blink and you'll miss moment after 0.28, where Lude falls on the ground and Leroy looks around for him. If you slow down the video, you'll see that when he bends toward him, their faces touch.
- Also, Narcisse complimenting Ohnaka's tattoos and touching his chest (much to Ohnaka's dismay)
- Uncanny Valley: Oddly enough, the more human-looking Midians (ie. the guy with the crescent-shaped head) are much creepier than the ones who look just plain demonic.