- Canon Sue: Nicholas, Kate and their love interests.
- Ho Yay: Nicholas and Smike, the mentally handicapped orphan he meets at Dotheboys Hall and later rescues.
Nicholas: My heart is linked to yours.
- Les Yay: Madeline initially has "a warmer feeling" for Kate than for Nicholas; it's implied that she mainly falls for him because of his resemblance to his sister.
- The Woobie: Smike.