YMMV / Nack And Psycho

The Scrappy: In-Universe, Ozzie, Flea, and Slash (of Chrono Trigger fame) alongside Control Freak, Elmyra, Montanta Max, and the Amoeba Boys, are this.
http://tvtropes.org/pmwiki/pmwiki.php/YMMV/NackAndPsycho