Alternate Character Interpretation: The Biker aliens run a school in their home planet. They do everything to benefit their society. On weekends, they take their stress out on Earth.
Sheldon expresses a near-obsessive infatuation for Jenny, but he was quick to fall for Vexus when she swindled him (and even tried to share a romantic dance with a toaster when Jenny wasn't dancing with him at a party). Does Sheldon really love Jenny, or are his feelings solely based on both desperation and robot fetishism?
Base Breaker: Sheldon. Beyond being the cause of a number of shipping arguments (Jenny/Brad vs Jenny/Sheldon), there are those who see him as a creep and those who think he's Adorkable, especially with him being the only one who actually believes Jenny was innocent in the Christmas episode.
Some hate The Crust Cousins for being so darn cruel to Jenny but with that being said, there are people who love them and/or just their wardrobe.
The random song Brad and Jenny sing in Humiliation 101
Crossover: Jenny is often drawn with/as Hatsune Miku, due to both characters being virtual and wearing teal pigtails and short skirts.
Crossovers with Robot Jones are common (sometimes it's a Crossover Ship) as Rob Renzetti worked on the short-lived Cartoon Network series while Robot Jones creator Greg Miller worked on Rob's series. Though in all honesty, Jenny's been crossovered with pretty much every cartoon robot from Bender to EVE to BMO to The Iron Giant. Hell, even some non-cartoon ones like R2-D2.
Hilarious in Hindsight: "Unlicensed Flying Object" features an alien threatening to swat Jenny, Brad and Tuck with a glorified electric flyswatter. Two years later, real electric flyswatters would gain popularity.
Les Yay: Jenny and Vexus' daughter Vega in the finale. Also Jenny and Misty.
Moe: Jenny, whose insecurities and innocence are very endearing.
Sacred Cow: Chances are if anyone acts like a jerk to Jenny on the show, they'll get called out for it by the fans on the spot.
The Scrappy: ...Seriously Tremorton, Can you at the very least show some respect for Jenny instead of constantly treating her like a mistake!?
"Killgore" has a brief moment where Jenny tries to get rid of the titular character, only for the other teens to glare at her and Panteresa to call her "a heartless freak", it's so much that the poor girl ends up running away in tears and claims that Killgore is better than her. Ouch...