These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Base Breaker and Internet Backdraft: When the show is brought up, expect people to take sides between the two title characters and fight to the death. Max is generally the one most people root for, but Ruby has a strong fanbase too.
Designated Monkey: Ruby likes to screw Max over. He's very good at screwing her back.
Memetic Mutation: Max's wide variety of facial expressions come which come across as rather devious for a cartoon character
The Scrappy: Both of the title characters, as Max is either getting into trouble, or Ruby tries to stop him from having fun no matter what he does.
The grandmother isn't liked as well, this is due to being really off with being the only damn character with colored eyes and just having a rather...uncomfortable vibe about her.