Narm: Since the show tends to portray the infestations in as overly-dramatic a manner as possible, they tend to fall under this sometimes. Making a cockroach/rat/bat infestation (even if it is really disgusting) look like the hellspawn are invading someone's home is rather cheesy at times.
Nausea Fuel: Several of the infestation stories are sickening enough to make your skin crawl.
Cockroach infestations in particular. Each story starts with the family only noticing a few crawling around the floor, and then it escalates into them crawling all over everything... including food in the fridge.
The story about the home that got infested by Argentine ants. A few crawling around outside is normal. Several crawling around on a BBQ is gross but not unheard of. Hundreds crawling around a kitchen is disgusting. Taking a swig from a water bottle and spitting out 20 ants is horrifying. And, thousands of ants crawling all over you while you're taking a bath (and you happen to be a small child) is too disgusting for words.
Nightmare Fuel:Just the very thought of a home being infested by deadly spiders, scorpions, or disease-carrying pests like rats and cockroaches can give people the shivers.
Paranoia Fuel: Your house could be infested by hundreds (if not thousands) of cockroaches, rats, ants, etc. and you may not know about it until it's too late.
Scorpions and brown recluse spiders are especially subject to this. Especially since they're both highly venomous.
And once the bugs are there, they have a nasty tendency to get everywhere. Like up your ear, if you're the woman in one of the episodes featuring cockroaches. In the same episode, the viewer is also treated to a lovely shot of roaches crawling over a baby in her crib. Yeek.
Squick: Many many of the stories featured will make your skin crawl. Ranging from the sheer number of waste some animals produce to the damage a spider bite can do to your flesh.
One episode featured a little girl who became covered in ants...in her bath tub. *Shudder*
Pretty much any time a house is infested with cockroaches. Those things end up everywhere.