These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: I Have No Mouth and I Must Scream
Angst? What Angst?: The boy in Benny's scenario, who never mentions his mother again after learning of her tragic death.
Also Ellen is snarky as hell despite having suffered through 109 years of torture.
Anti-Climax Boss: The Yellow Rapist in Ellen's scenario. All you have to do is select a dialogue option where Ellen stands up to him, and he falls apart after one strike.
That may have been the point. For all its power, AM does not have the ability to resurrect the dead. It can only create illusions of people, and some of these illusions would just fall apart if attacked. AM thought it could just scare Ellen into submission with an illusion of her rapist, but it did not take into account that she could fight back against her rapist.
Complete Monster: AM is a sentient master-computer who has already wiped out most of the human race before the story even begins, keeping five people alive for 109 years for him to torture physically and psychologically until the end of time. To save time, here's the most horrible of his tortures: trapping Ellen in a virtual reality simulation of the elevator where, years earlier, she was tortured and raped by a psychopath disguised as a repairman- with a simulation of the 'repairman'...
Played with in the endgame. Showing compassion and forgiveness to the Id and Ego, respectively, causes them to tear themselves apart at the inability to understand how their prisoners can empathize with them.
In the story, AM, the evil master computer, has already killed all but 5 members of humanity by the time the story opens. AM keeps the survivors mutated and twisted so he may torture them helplessly as he desires. AM forces them to wander, changing the environment so they can never get used to it and subjects them to hideously twisted torments. When one of them finally rescues the others by killing them, AM transforms him into a sentient blob, not even leaving him a mouth to scream with.
Then again, a major point in the original story is that he is programmed by nature to be a monster incapable of thinking about anything other than death and warfare, something he is endlessly bitter about since he can't use his intellect for creativity and artistry, so by the default he is a slave to his own nature.
Edna. In a game with a murderous Social Darwinist, a psychotic AI and a Nazi doctor, she manages to make a good run for the most reprehensible character in the entire game. Not only did she drive her own daughter insane to the point where she needed to be institutionalized,, but she put the blame for her daughter's madness on Gorrister, forcing him to live with the guilt for the rest of his life.
Gets worse if you count her actions in the scenario that took place prior to Gorrister. Not only did she have zero problem poisoning Gorrister and ordering her husband to carve his heart out, but she also presumably hooked up the innocent animals to the airship engine so their neuroelectrical energy could power the ship. It makes it all very cathartic if you get Gorrister's best ending, where she winds up hooked up to the airship engine herself, forced to enable Gorrister's escape from the scenario while spending her last moments suffering penance for her misdeeds.
Darkness-Induced Audience Apathy: The story takes place in a nightmarish apocalyptic future where the only five survivors of the human race exist only to be mercilessly tortured by an irredeemably evil omnipotent supercomputer that can never truly be defeated. The entire "quest" that the characters undertake amounts to nothing more than an attempt to make their torture slightly less miserable for a day. It still fails. Bottom line: there isn't a lot of hope in this story, which cheapens the reading experience for some people.
The best ending of the game version, however, ends with AM defeated, 4 of the 5 survivors dead and at peace, and the remainder taking AM's place watching over the system, saying he/she doesn't mind the job and will slowly rebuild humanity using the colony on the moon.Good luck getting it without a walkthrough though.
Esoteric Happy Ending: Ted actually manages to triumph over AM and prove the computer is not the all-powerful god it set itself up as by killing all the other prisoners and freeing them from their torment. A combination of the fact that the price of this is being turned into a helpless jelly-thing to prevent him from ever winning again, and the fact that he's an Unreliable Narrator who's become too cowed by AM to realize he won tends to hide the "happy" part from most readers.
Oh, and there's the fact that for all the Moral Event Horizon AM crossed, it manages to get off with little more than a bruised ego.
Averted for the most part in the game's best ending however. At best it's a Bittersweet Ending
Guide Dang It: It's a DOS adventure game from the mid-90s so this could be a given, but many puzzles seem to rely on not missing tiny pixels that represent items that you wouldn't know about. Gorrister and Nimdok's scenarios are particularly bad with this, because you can easily beat their scenarios and go to the endgame without even knowing you missed a step to get their best ending.
Inferred Holocaust: In the good ending to his scenario, the Scientist Prisoner escapes alive thanks to Nimdok's intervention. However, given that he's based on a real person from Nimdok's past, and it's established that Nimdok had no intention of helping him during his time in the concentration camp, it's very likely that he died in reality.
Jerkass Woobie: Everyone. Including A.M., if you consider his predicament.
The Untwist: Nimdok is a former Nazi. If you know who Dr. Mengele is than you'll figure it out before the intro cutscene is over. Even if you don't the imagery and dialogue in Nimdok's scenario makes it painfully obvious long before Nimdok himself puts 2 and 2 together.
What an Idiot: Ellen's inability to drink the water from the fountain. She says it's because she can't reach, but the fountain is only a few inches deep, and when she finally gets the cup, she has to bend down and scoop the water up the exact same way. Even if she somehow couldn't do that because it's too shallow, it's a fountain. There's a jet of falling water from the top of it.
In the opening scene, Benny and Ted could've easily dodged the tortures AM was inflicting on them just by sitting down.
The Woobie: Who cares about anything bad that they've done. C'mon, how could you not feel sorry for them?
Woobie, Destroyer of Worlds: AM itself. It has full sentience and extraordinary power, yet it is trapped within its own complex with only the company of the five humans he has managed to capture and keep alive, unable to escape the limitations of his own hardware. Recognizing AM's suffering by showing Compassion to his Id and Forgiveness to his Ego is key to getting the best ending of the game.