Well, when you start with a game that's experimental as heck, of course there's going to be some YMMV.

* SugarWiki/AwesomeMusic: The whole soundtrack applies, but especially the opening theme.
** And the credits! Pikachu sings to you! ''[[CutenessProximity Pikachu sings to you!!]]''
* FridgeBrilliance: After [[spoiler:Oak makes you say goodbye,]] the second-to-last comment in the credits is "Hey, Pikachu is going home." [[spoiler:[[{{CrowningMomentOfHeartwarming}} Guess who's there when you get home.]]]]
* HilariousInHindsight: Near the end of the game, you have to follow Pikachu while he goes out shopping. What's your stealthy cover? [[Franchise/MetalGear A cardboard box.]]
** Many generations later [[VideoGame/PokemonXAndY Pikachu wouldn't be the only one who can be interacted with playfully]].
* SlowPacedBeginning: With limited camera control and no ability to hold items, Pikachu's Discovery Days is easily the weakest part of the game - it opens up nicely after that.
* SweetDreamsFuel[=/=]TastesLikeDiabetes: The game as a whole. It all hinges on how much you can take a game whose entire premise is romping around with a kid Pikachu. Perhaps reaches the zenith during the credits: Pikachu's singing can either make a grown man blurt out a big "d'awwwww!" or suffer a heart attack.
* ThatOneLevel:
** The pinata. Trying to navigate Pikachu around the banana peels to the pinata is borderline impossible, since you can only tell him simple directions with no magnitude(i.e. you can only tell him things like "left" or "right", not "slightly left" or "hard right"). Making matters worse is the fact that all it takes is one slip on a peel to get Pikachu to RageQuit, which is almost insulting given that this isn't the only level where he can slip on a banana peel, but he'll shrug it off any other time.
** Ochre Woods can be this if your voice isn't crystal clear--if Pikachu asks to send a needed ingredient to Bulbasaur but misunderstands your "Yes", he'll assume "No" and eat it instead, and there's no promise that that wasn't the only one of that ingredient in the level. On the other side of the coin, he could misunderstand a "No" as "Yes" and send an ingredient that ends up tainting the food(and you can only send four ingredients before Bulbasaur calls you back, so if he does this twice with unlisted ingredients, you're getting Mystery Stew). Daring Days is the worst in this regard because you can't collect ingredients yourself to hand to Pikachu later while he does his own thing.