Complete Monster: Lord Moebius is the absolute ruler of Labyrinth. He wishes to expand his rule and control all the parallel worlds in existence. The people that live under his rule are forced to comply to his every order or risk death due to him directly controlling their lifespans. Labyrinth is a place where free will is not allowed, and happiness does not exist in. Moebius sends his most loyal subjects to attack Earth and create sorrow among the populace in order to find the power he needs to control the worlds. Not even those subjects are safe from him. Eas tortures herself nearly to death to defeat Pretty Cure by his command, and when she fails he ends her lifespan almost immediately. Later he tries to kill Westar and Soular in an attempt to get rid of a couple Cures slightly faster, even though they had been nothing but loyal to him the whole time. When he gains the necessary power, he takes control of all the worlds and turns the people into his mindless slaves. Eventually it's revealed he was an A.I. created to take care of the people of Labyrinth, before he decided they would be better off under his complete command, arrogantly believing that they would live more worthwhile lives with their souls controlled by him. Once defeated Moebius is asked what makes him happy. He answers that he regrets not being able to control Pretty Cure and blows himself up in an attempt to kill them.
Ensemble Darkhorse: Inori is incredibly popular amongst Japanese fandom, constantly scoring high in popularity polls and even claiming the #1 spot with a substantial lead in the 2012 General Pretty Cure Election.
The 2013 Favorite Precure instead is the "other" most popular character from this series: Setsuna.
Setsuna also won the 2014 Precure Popularity poll!
Memetic Mutation: Copypasting the title of episode 21, "The Fourth Pretty Cure is You!", over shots of different characters, most of the time even from other shows.
Due to Artistic Age and how the Precures in this season are drawn with slightly bigger bust (it is not that much), it becomes a fandom Running Gag to draw every other Precures suffering A-Cup Angst against the Fresh Precures, with the latter possibly suffering D-Cup Distress to justify.
Moebius crosses it for sure when he orders the deletion of Soular and Westar, two of his most loyal servants, along with Cures Passion and Berry just because he felt they were no longer useful to him. Love must've been quite a saint that she still thinks that after all those, Moebius still deserve to 'find his own happiness'. He does, and he decided that his happiness is 'dead Precures'. Cue a failed Taking You with Me.
In episode 46, Westar and Soular get sucked into a hole that will supposedly delete/kill them after saving Cure Passion and Cure Berry, respectively, from having the same fate. Two episodes later, we find that they weren't dead after all.
A meta Tear Jerker in the form of the death of Ken Maeda, the voice actor for Kaoru-chan, in April 2016.