These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Bifauxnen: Suzette may appear somewhat androgynous, which (some speculate) is why her crazy mother occasionally confused her for her older brother. However, within the story itself, it's a bit more likely that this was more a result of Sanity Slippage.
Crowning Moment of Heartwarming: The ending. While Keats seems to just sort of dismiss Ellen to focus on his "work", you can see in her eyes and smile that she knows how much both love each other. Also, the fact that Keats so easily accepts being a Halflife, just because he knows Ellen created him because she NEEDED him.
Goddamned Boss: Brigantia is not a powerful boss; in fact, compared to most of the unforgiving boss fights the game throws at you, it's remarkably weak. What Brigantia's battle is, however, is INCREDIBLY time-consuming. The boss will only stand and fight for a little while as you slice off one segment of its body after another; most of the fight will be spent waiting for the damn thing to pop out of a hole and hang around long enough to get a few hits in instead of hiding out of reach and throwing one wave of bombs after another at you or simply swimming right from one hole to the next. To make matters worse, you can only target his head, making it that much more difficult to hit the vulnerable parts at the end of his body.
Guide Dang It: The sections in the Endless Corridor's maze where you have to follow Habetrot can get frustrating because even if you follow the right one, one mistake can reset your progress and you have to go through the process and the battles again.
There's a variety of very creepy scenes and places in this game, but the standout example is Ellen's Mysterious Protector Scarecrow absorbing all the fear in the world and transforming into a horrible Eldritch Abomination. Honorable mention goes to Fleshrum, a Folklore that appears as a room made out of human flesh and body parts.
The description of some folks are often very unsettling.