These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
However this seems to be only a Vocal Minority as most seem to find Blood Dragon better. The facts that there are already talks of a sequel support this.
The split is largely between gamers who grew up in the '80s (And as such get the references and nostalgia better) and more modern gamers of the '90s and the 2000s, who think of it as a bit too... nutty, and just can't wrap their head around how this is supposed to be connected to Far Cry 3.
And gamers from the latter era who, even though they think it's completely incomprehensible, still love it and think it's hilarious.
Ear Worm: Power Glove's soundtrack is bound to stick with you for a while. Special mention goes to Warzone, which sounds close to the theme of The Terminator.
Genius Bonus: "Aaah! It's an exothermic chemical reaction!" (He means fire).
Hilarious in Hindsight: Back during Yahtzee's review of Far Cry 3 he made a joke about how you don't unlock the "magic pussy laser" (Yahtzee uses a picture of a tiger shooting lasers out of its eyes to illustrate this idea) until the end of the game. Amusingly Rex does unlock a magic laser during the end of the game, the Killstar device which allows him to fire a massive death ray from his left hand along with the Battle Armored Dragon Assault Strike System which is a dinosaur that does shoot lasers out of its eyes.
Ho Yay: Rex and Spider. The opening scene between the two of them should spell it out pretty well.
Narm Charm: It's an over-the-top parody of cheesy 80's action movies. This game wouldn't even be half as good as it is if weren't so incomprehensibly stupid.
Spiritual Licensee: It's one of the best Duke Nukem games ever made. Deliberately cheesy one-liners, nostalgia and lots of fun gunplay: check check check.