These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Darkness-Induced Audience Apathy: This is one of the facts that really hurted the movie as a whole: Despise being a comedy, practically everyone is an asshole, a wacko, or a pervert in some degree and most of the Toilet Humor is used for the hell of it rather to have some sense in the plot of the film. The only sympathetic character is Corporal Valdivia and he's the designated Butt Monkey. Another fact that alienated the Mexican audience is the not-so-implied message the so-called heroes and the audience watching the film are Not So Different. This is somewhat intended by Word of God, as Trino was trying to show almost every single negative stereotype the Mexicans has about themselves and raised Up to Eleven.
Just because you're a Jerk Ass doesn't give you the right to ruin the lives of the people who are smarter and better than you.
The animated film gives another message who is also a subversion of the first two: Even if you want to change the "retrograde" mentality of your countrymen, trying to doing that by violent or vile means will make you even worse than the people you're trying to supposely "educate".
What Do You Mean, It's Not Political?: Despise the over-the-top tone of the comic book (and also the movie), both Trino and Jis always cram some kind of political and social criticism in their stories, while avoiding reaching Rius-like level of criticism and always doing that with a sense of humor, no matter how crass can be.