These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Tear Jerker: Manga volume 13 - Stage 3, vol 21: Daisuke's reaction to Satoshi telling him that his family are cursed to die young is to almost break down into tears and say they have to do something while clinging to Satoshi's arm. Satoshi is absolutely shocked - has a flashback montage of many happy moments spent together with Daisuke - and then does the closest thing to a fond smile he can do. The Ho Yay shoots back Up to Eleven for the whole chapter, but in a very, very serious and heartbreaking way for once.
Stage 4, vol 14 is also quite the Tear Jerker, and in quite the same fashion as above; if you didn't think Satoshi was a Woobie before, you sure do think so now.